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The map label for this gene is fbp [H]

Identifier: 188528324

GI number: 188528324

Start: 1555087

End: 1555959

Strand: Direct

Name: fbp [H]

Synonym: HPSH_07980

Alternate gene names: 188528324

Gene position: 1555087-1555959 (Clockwise)

Preceding gene: 188528321

Following gene: 188528325

Centisome position: 96.68

GC content: 38.49

Gene sequence:

>873_bases
ATGGATTACAAACATTTTAAAGGCAAGCATGCAAACATCGTTATAGAAATCATTAGTCTTTTAGAAAAAGGGGTTAAAAA
AGCCCAAGAGATTTTAGAAAAGCCGGACGCTGGGAGTTACACCAAGCTAGAAAACAGCAGCGGGGATACGCCCATTAAAG
CGGATTTAGCCCTAGACAAATTTTTAGAAGAAAATTTTTTGAGTTTAGAAAATGTGAAAAGCGTTTTTAGCGAAGAAAAA
GAAACGCCTGTTACTAAAGAAAACGGCTCTTATTTGATCGCTTATGACCCACTAGATGGGAGCTCAGTGATGGAGGCGAA
TTTCTTAGTAGGCACGATTATAGGGGTTTATGAAAAGGATTATAAGGCGCAAAATTTAGCCGCCAGCCTTTATGTGGTTT
TTGGGCATAAAATAGAACTGGTGGTGGCTTTAGAAGAAGTTTATCGTTACGGGTTTTACCAGAACAAGTTCCATTTTATA
GAAACCATTGTTTTAGAAAATAAGGGTAAAATCATCGCTAGCGGAGGCAATCAAAAGGATTTTTCTTCGGGCTTAAAAAA
GGCTTTAGAAGGGTTTTTTGCAGAAAATTACCGCTTACGATACTCAGGATCTATGGTGGCTGATGTCCATCATGTGTTGA
TTAAAAAAGGCGGAATGTTTTCCTACCCGCAAAAGAAATTGCGCAAGCTTTTTGAAGTCTTTCCTTTAGCCTTGATGGTT
GAAAAAGCTAAAGGGGAAGCGTTTTATTTTGATAAGGGGGTGAAAAAGCGCCTGCTAGAGCAAAGCGTAGAAAGCTACCA
TGAAAAAAGCGAATGCTATTTAGCTAGCCAGCATGAAGCTCACATCTTAGAAAAATATTTAAAGGGAGAATGA

Upstream 100 bases:

>100_bases
AGCGCTCAAAAGGCTCGGAGCTACTTTCAAAATACTTCCCTATTTCCAATGTTTTCAAGTAAAATATTAGCATCTTTAAT
CAAATCATAAAAGGGTTTTT

Downstream 100 bases:

>100_bases
TGCAAAATAGCGCTAAAAAATTAGAATATGAAGAGCGTTTTAATGACGCTCTTTTGAAATTGCAAGCATGCCAAGAAGAA
AAACAAGTAGCGAGTTGCTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENVKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGVYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYGFYQNKFHFI
ETIVLENKGKIIASGGNQKDFSSGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASQHEAHILEKYLKGE

Sequences:

>Translated_290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENVKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGVYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYGFYQNKFHFI
ETIVLENKGKIIASGGNQKDFSSGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASQHEAHILEKYLKGE
>Mature_290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENVKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGVYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYGFYQNKFHFI
ETIVLENKGKIIASGGNQKDFSSGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASQHEAHILEKYLKGE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=309, Percent_Identity=28.4789644012945, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI16579888, Length=309, Percent_Identity=28.4789644012945, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI22907028, Length=313, Percent_Identity=26.8370607028754, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790679, Length=278, Percent_Identity=29.4964028776978, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17508131, Length=321, Percent_Identity=26.4797507788162, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323409, Length=275, Percent_Identity=29.4545454545455, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921562, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550998, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR023079 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 32900; Mature: 32900

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENVKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGVYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
YKAQNLAASLYVVFGHKIELVVALEEVYRYGFYQNKFHFIETIVLENKGKIIASGGNQKD
HHHHHHHHHEEEEECCEEEEEHHHHHHHHHCCCCCHHHHHHEEEEECCCEEEECCCCCHH
FSSGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALMV
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASQHEAHILEKYLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENVKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGVYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
YKAQNLAASLYVVFGHKIELVVALEEVYRYGFYQNKFHFIETIVLENKGKIIASGGNQKD
HHHHHHHHHEEEEECCEEEEEHHHHHHHHHCCCCCHHHHHHEEEEECCCEEEECCCCCHH
FSSGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALMV
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASQHEAHILEKYLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA