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The map label for this gene is murQ

Identifier: 187934881

GI number: 187934881

Start: 3162314

End: 3163219

Strand: Reverse

Name: murQ

Synonym: CLL_A3059

Alternate gene names: 187934881

Gene position: 3163219-3162314 (Counterclockwise)

Preceding gene: 187935065

Following gene: 187934745

Centisome position: 83.24

GC content: 30.57

Gene sequence:

>906_bases
ATGGGTAGTATAATTGATAATCTTGAAACAGAAAAAAGAAATATAAATAGTGAAAATATAGATATTATGAGTACATGTGA
AATTATTAAAACTATAAATTCTGAAGATAAAAAAATTGCGTACGCAATTGAAAAGGTTATTCCTGAAATTGAAAAATTAA
TTGATGCAACTTATGAAAAAATGTTATTTGGGGGGAGAGTTATATATATAGGAGCAGGTACTTCAGGGAGACTTGGAGTT
TTAGATGCCAGTGAGTGTCCTCCAACTTATGGAGTTGATGCGTCTTTAGTTCAAGGAATTATTGCAGGAGGATATGGTGC
TTTATTAAAAGCTAAAGAAGGTGCAGAAGATTCATTAACTCTTGCAAAAGAAGATTTAAAAGAGATTAAACTAAATTCTC
ATGATACTGTCATAGGATTAGCAGCAAGTGGCAGAACTCCTTATGTAATTGGTGGATTAGATTATGCAAATGAAATAGGT
GCTTTAACTGGAGCTATTTCTTGTGTAAACAATGCTCAAATTAGTCAACATGCTAAATATTTTATTGAAGCTATTGTTGG
TGCAGAAGTAATAACAGGTAGCACTAGGATGAAGGCCGGTACGGCTCAAAAAATGATTCTAAATATGATTTCTACATCTC
TTATGATAAAAAAAGGAAAAGTGTATCATAATTTAATGGTTGATGTTCAGCCAACCAATAAAAAATTAATAGAACGTTCT
AAAAATATAATTGCAGAGTGTACAAATTCGTCTGTAGAAGAAGCAGAAAAAGCATTAATTGATAGCGGAAATCAGGTTAA
AGTTGCGATGCTTATGTTGCTTACAAAGAAAGATAAGAAATCTTGCATTAATATTTTAAATGAAAATGATGGAAATATTT
CAAAATCAATCAGAAATATTCCTTAA

Upstream 100 bases:

>100_bases
CTTATTATTTACAACACAATTTTAGCTGTGTATATCTTGAAAATTTATTCCAAAAATTGTATAATTCAATAAATTAATAA
TATTTTAGGAAGTGATATGA

Downstream 100 bases:

>100_bases
ATGGTTTACTGCAGTTTAAATTAAAAGTTAGTAATGCCATGTTTCTATGTTATTTGCATATATAATCTTAAAGGTATTAT
AAGTTGCAATACATCTAAAA

Product: N-acetylmuramic acid 6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGSIIDNLETEKRNINSENIDIMSTCEIIKTINSEDKKIAYAIEKVIPEIEKLIDATYEKMLFGGRVIYIGAGTSGRLGV
LDASECPPTYGVDASLVQGIIAGGYGALLKAKEGAEDSLTLAKEDLKEIKLNSHDTVIGLAASGRTPYVIGGLDYANEIG
ALTGAISCVNNAQISQHAKYFIEAIVGAEVITGSTRMKAGTAQKMILNMISTSLMIKKGKVYHNLMVDVQPTNKKLIERS
KNIIAECTNSSVEEAEKALIDSGNQVKVAMLMLLTKKDKKSCINILNENDGNISKSIRNIP

Sequences:

>Translated_301_residues
MGSIIDNLETEKRNINSENIDIMSTCEIIKTINSEDKKIAYAIEKVIPEIEKLIDATYEKMLFGGRVIYIGAGTSGRLGV
LDASECPPTYGVDASLVQGIIAGGYGALLKAKEGAEDSLTLAKEDLKEIKLNSHDTVIGLAASGRTPYVIGGLDYANEIG
ALTGAISCVNNAQISQHAKYFIEAIVGAEVITGSTRMKAGTAQKMILNMISTSLMIKKGKVYHNLMVDVQPTNKKLIERS
KNIIAECTNSSVEEAEKALIDSGNQVKVAMLMLLTKKDKKSCINILNENDGNISKSIRNIP
>Mature_300_residues
GSIIDNLETEKRNINSENIDIMSTCEIIKTINSEDKKIAYAIEKVIPEIEKLIDATYEKMLFGGRVIYIGAGTSGRLGVL
DASECPPTYGVDASLVQGIIAGGYGALLKAKEGAEDSLTLAKEDLKEIKLNSHDTVIGLAASGRTPYVIGGLDYANEIGA
LTGAISCVNNAQISQHAKYFIEAIVGAEVITGSTRMKAGTAQKMILNMISTSLMIKKGKVYHNLMVDVQPTNKKLIERSK
NIIAECTNSSVEEAEKALIDSGNQVKVAMLMLLTKKDKKSCINILNENDGNISKSIRNIP

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=291, Percent_Identity=51.8900343642612, Blast_Score=287, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_CLOBB (B2TPW8)

Other databases:

- EMBL:   CP001056
- RefSeq:   YP_001887245.1
- ProteinModelPortal:   B2TPW8
- GeneID:   6295119
- GenomeReviews:   CP001056_GR
- KEGG:   cbk:CLL_A3059
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32428; Mature: 32297

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 85-85 ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSIIDNLETEKRNINSENIDIMSTCEIIKTINSEDKKIAYAIEKVIPEIEKLIDATYEK
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFGGRVIYIGAGTSGRLGVLDASECPPTYGVDASLVQGIIAGGYGALLKAKEGAEDSLT
HHHCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHH
LAKEDLKEIKLNSHDTVIGLAASGRTPYVIGGLDYANEIGALTGAISCVNNAQISQHAKY
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
FIEAIVGAEVITGSTRMKAGTAQKMILNMISTSLMIKKGKVYHNLMVDVQPTNKKLIERS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHH
KNIIAECTNSSVEEAEKALIDSGNQVKVAMLMLLTKKDKKSCINILNENDGNISKSIRNI
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCC
P
C
>Mature Secondary Structure 
GSIIDNLETEKRNINSENIDIMSTCEIIKTINSEDKKIAYAIEKVIPEIEKLIDATYEK
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFGGRVIYIGAGTSGRLGVLDASECPPTYGVDASLVQGIIAGGYGALLKAKEGAEDSLT
HHHCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHH
LAKEDLKEIKLNSHDTVIGLAASGRTPYVIGGLDYANEIGALTGAISCVNNAQISQHAKY
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
FIEAIVGAEVITGSTRMKAGTAQKMILNMISTSLMIKKGKVYHNLMVDVQPTNKKLIERS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHH
KNIIAECTNSSVEEAEKALIDSGNQVKVAMLMLLTKKDKKSCINILNENDGNISKSIRNI
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA