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The map label for this gene is mnmG

Identifier: 187930588

GI number: 187930588

Start: 3693288

End: 3695237

Strand: Reverse

Name: mnmG

Synonym: Rpic_3523

Alternate gene names: 187930588

Gene position: 3695237-3693288 (Counterclockwise)

Preceding gene: 187930589

Following gene: 187930587

Centisome position: 93.73

GC content: 64.36

Gene sequence:

>1950_bases
ATGCTGTATCCAATTGAATTCGATGTGATCGTGGTGGGCGGCGGACACGCCGGCACCGAGGCCGCCCTGGCGGCGGCGCG
CATGGGCTGCCAGACCCTGCTGCTGACGCACAACATCGAGACCTTGGGGCAGATGAGCTGCAATCCGTCCATCGGCGGCA
TCGGCAAGGGTCACCTGGTCAAGGAAGTGGATGCGCTCGGCGGCGCCATGGCCATTGCGACGGACGAGGGCGGGATCCAG
TTCCGTATCCTCAATTCCAGCAAGGGCCCGGCCGTGAGGGCGACTCGCGCGCAGGCAGACCGCGTGCTGTACAAGGCGGC
GATCCGTCATCGCCTGGAAAACCAGCCGAACCTGATGCTGTTCCAGCAGGCTGTGGAAGACCTGGTGGTAGAAGGCGATC
GCGTAATCGGGGCGGTGACGCAGGTTGGCGTGCAGTTCCGTGCACGTGCTGTGGTACTGACGGCCGGCACGTTCCTCGAC
GGCAAGATCCACGTCGGGCTAAACAACTACACCGGCGGTCGCGCGGGCGACCCGGCTGCGGTATCGCTGTCGGCGCGTCT
GAAGGAATTGAAGCTGCCGCAAGGCCGCCTCAAAACCGGCACGCCGCCGCGCATTGACGGCCGCTCCATCGATTTTTCGG
TGCTCGAAGAGCAGCCGGGTGATCTCGATCCGGTGCCGGTGTTCTCGTTCATGGGCCGCGCGGACATGCATCCGCGTCAA
GTGCCGTGCTGGGTAACGCACACCAACGAGCGCACGCACGACATCATCCGCGCCGGGCTGGACCGCTCCCCCATGTACAC
GGGCGTGATCGAAGGGGTGGGGCCACGCTACTGCCCTAGCATTGAAGACAAGATCCATCGCTTCGCCAGCAAGGACAGCC
ACCAGATCTTCCTGGAACCGGAGGGCTTGGCGACCAACGAGTTTTACCCGAACGGCGTGTCGACCAGCCTGCCGTTTGAT
GTGCAGCTCGACCTGATCCACTCAATGCGCGGGCTGGAGAATGCCCACATCCTGCGTCCCGGTTACGCCATCGAGTACGA
CTACTTCGACCCGCGCGGCCTCAAGGCCTCGCTGGAGTCGAAGGCGATTTCCGGCCTGTTCTTCGCTGGCCAGATCAACG
GGACGACCGGTTACGAAGAGGCCGCGGCGCAAGGCCTGCTGGCGGGCATCAACGCCGGCCTGCAAGTGCAGGGCAAGGAT
GCCTGGACGCCGCGCCGCGACCAGGCTTATCTGGGCGTGCTCGTCGACGACCTCATCACCCGGGGCGTGACCGAGCCGTA
TCGCATGTTCACCAGCCGGGCCGAGTTCCGCCTCAGCCTGCGGGAAGACAACGCCGACATGCGCTTGACCGAAGTCGGCC
GCACGCTGGGCGTGGTCGACGACGCTCGCTGGGATGCCTTCAACCGGAAGCGTGACGCTGTTTCACGTGAAACAGAGCGC
CTCAAGTCGACTTGGGTGAATCCGGCCACGCTTCCGTTGGAAGACGCTGAGCCGGTCCTGGGCAAAGGCATTGAGCGCGA
GTACGCCTTGGCCGACTTGCTGCGCCGGCCTAACGTGACGTACGAAACCCTTGTGGGCATGCAGGGCGGCAAGTACGCGC
TCGAATCGCCGTTGGCTGAAGACCCGTTGCTGGCCGAGCAGATCCGCGAGCAGGTCGAGATCGGCATCAAATACCACGGC
TATATCGCCCGGCAAGCCGATGAAGTGGAGCGCCTCGGTGCGAACGAGAACACCCGTCTGCCGGCCGATTTCGATTATTC
GCAAGTGCGCGGTCTGTCGATCGAGGTCCAGCAGAAGCTCGCCAAGCACAAGCCCGAGACCATCGGACAGGCTTCACGTA
TCTCCGGCATCACGCCGGCCGCCGTGTCGCTGCTGCTCGTGCACCTCAAGAAGGGCGTGCTGCGTGGCCAAGTTGGCCCG
CGCGCCAGTTCAGAAGGCGAGGCCGCTTGA

Upstream 100 bases:

>100_bases
AATTTCGTCTCGATTACCGCATCGTCGAACTGTGGTGTAGCTGCGCGACTTATAATTCCGCTTCTCCAAATTTTCAATGC
CTCCATGCGAGGAGGAAGCC

Downstream 100 bases:

>100_bases
TGGCGAATGCACTGACAGACGCCCGGGCAGAGTTGGAAGCCGGCGCCCGTGCGCTTGGCTTGTCGCTGGACGACGCGCAG
GTCGATCGCCTGCTGGCGTA

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEGGIQ
FRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLMLFQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLD
GKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQ
VPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLATNEFYPNGVSTSLPFD
VQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLESKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETER
LKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAEDPLLAEQIREQVEIGIKYHG
YIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKLAKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGP
RASSEGEAA

Sequences:

>Translated_649_residues
MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEGGIQ
FRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLMLFQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLD
GKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQ
VPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLATNEFYPNGVSTSLPFD
VQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLESKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETER
LKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAEDPLLAEQIREQVEIGIKYHG
YIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKLAKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGP
RASSEGEAA
>Mature_649_residues
MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEGGIQ
FRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLMLFQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLD
GKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQ
VPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLATNEFYPNGVSTSLPFD
VQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLESKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETER
LKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAEDPLLAEQIREQVEIGIKYHG
YIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKLAKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGP
RASSEGEAA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=647, Percent_Identity=44.822256568779, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI19882217, Length=672, Percent_Identity=43.1547619047619, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI183227703, Length=687, Percent_Identity=42.2125181950509, Blast_Score=468, Evalue=1e-132,
Organism=Escherichia coli, GI2367273, Length=636, Percent_Identity=70.2830188679245, Blast_Score=907, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=636, Percent_Identity=40.7232704402516, Blast_Score=462, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321202, Length=630, Percent_Identity=45.2380952380952, Blast_Score=500, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24658174, Length=647, Percent_Identity=45.9041731066461, Blast_Score=502, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_RALPJ (B2UGW0)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001901075.1
- ProteinModelPortal:   B2UGW0
- SMR:   B2UGW0
- GeneID:   6286796
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_3523
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 70810; Mature: 70810

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLV
CCCEEEEEEEEEECCCCCHHHHHHHHHHCHHEEEEECCHHHHHCCCCCCCCCCCCCCHHH
KEVDALGGAMAIATDEGGIQFRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLML
HHHHHCCCEEEEEECCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
FQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAA
HHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEEECEEECCEEEEEECCCCCCCCCCCCE
VSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQ
EEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCCCCCC
VPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEP
CCEEEECCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECC
EGLATNEFYPNGVSTSLPFDVQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLES
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCHHHHH
KAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKDAWTPRRDQAYLGVLVDDLIT
HHHCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
RGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETER
HCCCHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAE
HHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHCCCCCC
DPLLAEQIREQVEIGIKYHGYIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKL
CCHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
AKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGPRASSEGEAA
HHCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLV
CCCEEEEEEEEEECCCCCHHHHHHHHHHCHHEEEEECCHHHHHCCCCCCCCCCCCCCHHH
KEVDALGGAMAIATDEGGIQFRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLML
HHHHHCCCEEEEEECCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
FQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAA
HHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEEECEEECCEEEEEECCCCCCCCCCCCE
VSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQ
EEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCCCCCC
VPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEP
CCEEEECCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECC
EGLATNEFYPNGVSTSLPFDVQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLES
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCHHHHH
KAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKDAWTPRRDQAYLGVLVDDLIT
HHHCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
RGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETER
HCCCHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAE
HHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHCCCCCC
DPLLAEQIREQVEIGIKYHGYIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKL
CCHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHH
AKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGPRASSEGEAA
HHCCCHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA