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The map label for this gene is fabH [H]

Identifier: 187735136

GI number: 187735136

Start: 740481

End: 741500

Strand: Direct

Name: fabH [H]

Synonym: Amuc_0630

Alternate gene names: 187735136

Gene position: 740481-741500 (Clockwise)

Preceding gene: 187735135

Following gene: 187735137

Centisome position: 27.79

GC content: 60.88

Gene sequence:

>1020_bases
ATGGCCGCACATTCTGATATTCCCTTTAAAAGACTGCCCGTCAAGATTATCGGTACGGGTTCCTATGTTCCGGAACGCCG
CCTGACCAATGCGGATCTGGAGAAGATGGTGGACACTTCCCACGAATGGATTATTGAACGCACGGGCATTGTGGAACGCC
GCATCGCCGCCCCTGACGAGTACACTTCCCATATGGGGACGAAGGCCGCCCAGCGCGCTCTGGAATCCTGCGGGCTGAAG
CCGGAGGATATTGACCTGATTATCGTCGCCACCATCACGCCGGATACGTTCACCCCTTCCACTTCCTGCTATATCCAGGA
TGCCCTTGGCGCCAAGAATGCCGCCGCCTTTGACATTTCCGCCGCCTGCTCCGGCTTCCTGTTCGCCATGAAGACCGCCG
TCCAGTACATCGGCACCGGCCAGATGAAAACGGCGCTCATCATCGCCGCTGAAAAACTTTCCACCGTCGTCAACTGGGAG
GACCGCAGCACCTGCGTCCTGTTCGGGGACGGCGCCGGGGCAGCCGTGCTCCAGGCTTCCACAGGGGAAGAGGGAGAAGG
TTCCGTCCTTGCCACGGATATCGGTTCGGACGGCTCCCTGCATGACCTGCTCCAGATTCCGGGCGGCGGCTCCCGCTGCC
CCACCACAGCGGAAAACGCCCATGAACGCCTGGCTACCCTGGCCATGCGCGGCAATGAGACCTTCCGCCATGCCGTCACG
CGCATGAAGGCTTCCGCCGCCAGCGTCATTGAACGCGCCGGCCTCACGGCGGACGATATCCAGCTGATTATTCCCCACCA
GGCCAATCTCCGCATCATTAACGCCGTAGCGCAGCGCCTTTCCATTCCTGAAGATAAGGTGTTCGTGAACATTGAGAAGT
ACGGCAACACGTCCGCGGCCGCCGTCGCCATCGCTTTTGACGAAGCGCGCCGTTCCGGCAGATTCGGCAAGGGAGACAAC
GTCGTCCTGGTCACATTCGGCGCCGGGCTTACCTGGTCCGCCGCCGTTATCCGCTGGTAA

Upstream 100 bases:

>100_bases
AGGAGTCCTGCGTTTTATGCTGGTCATCAGGCCCTCTTTCTTTTAGACTGTTTCCACATAAAACGTCAGGACGTTTTCTG
TTCATCATACGCCCAAAGCT

Downstream 100 bases:

>100_bases
TATTCTTTTTCACCCCCCCTCCATCATCATGACCACTGAACCATACGGCAAAAAAAATCCGTTTCCCGCTCCCGTCCTCT
CCGTCAGGCATATCACCGGG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAAHSDIPFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWIIERTGIVERRIAAPDEYTSHMGTKAAQRALESCGLK
PEDIDLIIVATITPDTFTPSTSCYIQDALGAKNAAAFDISAACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWE
DRSTCVLFGDGAGAAVLQASTGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHERLATLAMRGNETFRHAVT
RMKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLSIPEDKVFVNIEKYGNTSAAAVAIAFDEARRSGRFGKGDN
VVLVTFGAGLTWSAAVIRW

Sequences:

>Translated_339_residues
MAAHSDIPFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWIIERTGIVERRIAAPDEYTSHMGTKAAQRALESCGLK
PEDIDLIIVATITPDTFTPSTSCYIQDALGAKNAAAFDISAACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWE
DRSTCVLFGDGAGAAVLQASTGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHERLATLAMRGNETFRHAVT
RMKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLSIPEDKVFVNIEKYGNTSAAAVAIAFDEARRSGRFGKGDN
VVLVTFGAGLTWSAAVIRW
>Mature_338_residues
AAHSDIPFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWIIERTGIVERRIAAPDEYTSHMGTKAAQRALESCGLKP
EDIDLIIVATITPDTFTPSTSCYIQDALGAKNAAAFDISAACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWED
RSTCVLFGDGAGAAVLQASTGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHERLATLAMRGNETFRHAVTR
MKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLSIPEDKVFVNIEKYGNTSAAAVAIAFDEARRSGRFGKGDNV
VLVTFGAGLTWSAAVIRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=325, Percent_Identity=46.1538461538462, Blast_Score=282, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36134; Mature: 36003

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHSDIPFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWIIERTGIVERRIAAPDE
CCCCCCCCHHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCHHEEEECCCCHHHHCCCCHH
YTSHMGTKAAQRALESCGLKPEDIDLIIVATITPDTFTPSTSCYIQDALGAKNAAAFDIS
HHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCEEEHH
AACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWEDRSTCVLFGDGAGAAVLQAS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHEECCCCCCEEEEEECCCCCEEEEEC
TGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHERLATLAMRGNETFRHAVT
CCCCCCCCEEEEECCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
RMKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLSIPEDKVFVNIEKYGNTSAA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCE
AVAIAFDEARRSGRFGKGDNVVLVTFGAGLTWSAAVIRW
EEEEEEHHHHHCCCCCCCCCEEEEEECCCCEECEEEEEC
>Mature Secondary Structure 
AAHSDIPFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWIIERTGIVERRIAAPDE
CCCCCCCHHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCHHEEEECCCCHHHHCCCCHH
YTSHMGTKAAQRALESCGLKPEDIDLIIVATITPDTFTPSTSCYIQDALGAKNAAAFDIS
HHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCEEEHH
AACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWEDRSTCVLFGDGAGAAVLQAS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHEECCCCCCEEEEEECCCCCEEEEEC
TGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHERLATLAMRGNETFRHAVT
CCCCCCCCEEEEECCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
RMKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLSIPEDKVFVNIEKYGNTSAA
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCE
AVAIAFDEARRSGRFGKGDNVVLVTFGAGLTWSAAVIRW
EEEEEEHHHHHCCCCCCCCCEEEEEECCCCEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]