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The map label for this gene is ruvB

Identifier: 187735135

GI number: 187735135

Start: 739340

End: 740359

Strand: Direct

Name: ruvB

Synonym: Amuc_0629

Alternate gene names: 187735135

Gene position: 739340-740359 (Clockwise)

Preceding gene: 187735134

Following gene: 187735136

Centisome position: 27.75

GC content: 63.73

Gene sequence:

>1020_bases
ATGGGAGAGTCCTTTTACACACGCACCACGGAGGCCCCCTCCTCCGCCTTCGATTTGTCCCTCAGACCGCCCGCTTTCAG
CGAGTTCTGCGGCCAGGAAAAGATTAAGGACCGCCTGATGCTGATGGTGGAAGCCGCCAGACAGCGCGACGACGTGCTGG
ACCATATCCTGTTGAGCGGCCCGCCGGGCCTGGGGAAGACGACGCTTGCTAATATTATCGCGAATGCCGTCGGCTGCCGC
ATTCATACGACTTCCGGCCCCCAGATTGAAAAGGCGGGAGACCTGGCCGGCGTGCTGACCAATCTGGAAAAGGGGGATAT
TCTGTTTATTGACGAGATCCACCGCCTGCACCCGGCCATTGAGGAGTATCTGTACCCGGCCATGGAGGATTTCCGGCTGG
ATATTATCATCGACCAGGGGCCGAACGCCCGCTCCATCCAGCTCAACCTGCCCAAGTTCACCCTGGTGGGGGCCACCACC
CGCGCCGGGATGCTGACCAGCCCGCTGCGTTCCCGCTTCGGCCTGGTGAACCGGCTGGATTATTATACGCGGGAGGAGCT
GTGCGCCATTATCGAACGGTCCGCGGGGCTGCTGAACGTGCCCGTGGACCCGGAGGGCGCCCTGCAGATCGCGCTGCGCT
CCCGCGGCACGCCCCGCGTGGCCAATTCCCTGCTGCGCTGGGTGCGGGATTACGCCCAGGTGCGCGGCGACGGCGTGATT
ACGGAGCAGTTGGCGCACGATGCCCTGACCATGATTGAGATTGACGACGACGGCCTGGACGAGATGGACAAGCGCCTGCT
GGAAGCGATGATTTACAAGTTCAACGGCGGCCCGGTGGGCCTTTCCTCCCTGGCGGTGGCCGTAGGGGAGGACGCTTCCA
CGCTGGAGGACGTGCACGAGCCTTTCCTGATTATGCAGGGGTATATCAGCCGCACCCCCAGGGGGCGCGTGGCGATGCCC
TCCGCCTATCTCAAGATGGGAGCCGCGCCGCCCGCCAACGGCCAGGGGTGGCTGTTGTAA

Upstream 100 bases:

>100_bases
AAAAAAGGGCAAAGGCTTCCGGCATGTCCCGGAAAAGGCGTTTCCCGACCGCACTTCCCCCTTGACGGATGCCCCAAAGA
CGGGTTTGCTAGTCCTGCGC

Downstream 100 bases:

>100_bases
GCCATTCATTTACGACATGAAAGGAGTCCTGCGTTTTATGCTGGTCATCAGGCCCTCTTTCTTTTAGACTGTTTCCACAT
AAAACGTCAGGACGTTTTCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MGESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSGPPGLGKTTLANIIANAVGCR
IHTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAIEEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATT
RAGMLTSPLRSRFGLVNRLDYYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVI
TEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHEPFLIMQGYISRTPRGRVAMP
SAYLKMGAAPPANGQGWLL

Sequences:

>Translated_339_residues
MGESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSGPPGLGKTTLANIIANAVGCR
IHTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAIEEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATT
RAGMLTSPLRSRFGLVNRLDYYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVI
TEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHEPFLIMQGYISRTPRGRVAMP
SAYLKMGAAPPANGQGWLL
>Mature_338_residues
GESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSGPPGLGKTTLANIIANAVGCRI
HTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAIEEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATTR
AGMLTSPLRSRFGLVNRLDYYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVIT
EQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHEPFLIMQGYISRTPRGRVAMPS
AYLKMGAAPPANGQGWLL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=322, Percent_Identity=55.5900621118012, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_AKKM8 (B2UPI9)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877247.1
- GeneID:   6274189
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0629
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37174; Mature: 37043

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSG
CCCCCCCCCCCCCCCCEECEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLANIIANAVGCRIHTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAI
CCCCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
EEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATTRAGMLTSPLRSRFGLVNRLD
HHHHHHCHHCCEEEEEEECCCCCCEEEEECCEEEEEECCHHCCHHHHHHHHHHHHHHHHH
YYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVI
HHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCH
TEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHE
HHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHH
PFLIMQGYISRTPRGRVAMPSAYLKMGAAPPANGQGWLL
HHHHHHHHHCCCCCCCEECCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSG
CCCCCCCCCCCCCCCEECEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLANIIANAVGCRIHTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAI
CCCCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
EEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATTRAGMLTSPLRSRFGLVNRLD
HHHHHHCHHCCEEEEEEECCCCCCEEEEECCEEEEEECCHHCCHHHHHHHHHHHHHHHHH
YYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVI
HHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCH
TEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHE
HHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHH
PFLIMQGYISRTPRGRVAMPSAYLKMGAAPPANGQGWLL
HHHHHHHHHCCCCCCCEECCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA