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The map label for this gene is btuE [C]

Identifier: 186476112

GI number: 186476112

Start: 1520908

End: 1521396

Strand: Reverse

Name: btuE [C]

Synonym: Bphy_1354

Alternate gene names: 186476112

Gene position: 1521396-1520908 (Counterclockwise)

Preceding gene: 186476115

Following gene: 186476105

Centisome position: 43.73

GC content: 59.3

Gene sequence:

>489_bases
ATGGCAGACAAGTCTTCGATTTATTCCTTCTCGGCGCGCACGCTGGACGGCGAGCCGGTCAGCTTCGAACGTTACAACGG
CAAAGTGATGCTGATTGTCAACACGGCGAGCGAATGCGGTTTCACGCCGCAGTACGCCGGCTTGCAGAAGCTGCACGAGC
AATACGCGGCGCGCGGGCTGCAGGTGCTGGGTTTTCCGTGCAACCAGTTCGGCAAGCAGGAGCCGGGCGATGCGGCGCAG
ATCGGTGCGTTCTGCGAGAAGAACTATGGCGTGACGTTTCAGATGTTCGACAAGATAGACGTCAATGGTTCGGACGCGCA
TCCGCTCTTCAGGTTCCTGAAGGACGAAGCGCCCGGCGTGCTCGGACTCGAAGCGATCAAATGGAATTTCACGAAGTTTC
TGGTCGACCGCGACGGCAAGGTCGTCAAGCGCTACGCGCCCACCACGAAGCCCGAAACGATCACGGACGACATCGAGGCG
CTGCTGTAA

Upstream 100 bases:

>100_bases
TATTTTAGACTGCGCGGCGCACGCTCAGGCATTGGCCGATCGGCTAGGTGGCGCGCGGCCGCGGAGCCATTAGACTAACG
ACATTCCTGGAGGGCGGCAC

Downstream 100 bases:

>100_bases
CGGGCGTCAGAGAATCGGCGCGAACAAACGCGCAACGTGCATCAGCACGCGCCGCAGCGCCGGCGCGTTGCGATACTCGC
TGCGGTCTATCTCGTACGAT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MADKSSIYSFSARTLDGEPVSFERYNGKVMLIVNTASECGFTPQYAGLQKLHEQYAARGLQVLGFPCNQFGKQEPGDAAQ
IGAFCEKNYGVTFQMFDKIDVNGSDAHPLFRFLKDEAPGVLGLEAIKWNFTKFLVDRDGKVVKRYAPTTKPETITDDIEA
LL

Sequences:

>Translated_162_residues
MADKSSIYSFSARTLDGEPVSFERYNGKVMLIVNTASECGFTPQYAGLQKLHEQYAARGLQVLGFPCNQFGKQEPGDAAQ
IGAFCEKNYGVTFQMFDKIDVNGSDAHPLFRFLKDEAPGVLGLEAIKWNFTKFLVDRDGKVVKRYAPTTKPETITDDIEA
LL
>Mature_161_residues
ADKSSIYSFSARTLDGEPVSFERYNGKVMLIVNTASECGFTPQYAGLQKLHEQYAARGLQVLGFPCNQFGKQEPGDAAQI
GAFCEKNYGVTFQMFDKIDVNGSDAHPLFRFLKDEAPGVLGLEAIKWNFTKFLVDRDGKVVKRYAPTTKPETITDDIEAL
L

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=50, Blast_Score=152, Evalue=1e-37,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=50, Blast_Score=151, Evalue=2e-37,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=44.0251572327044, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=46.1538461538462, Blast_Score=136, Evalue=9e-33,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=50.381679389313, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI4557629, Length=185, Percent_Identity=41.0810810810811, Blast_Score=121, Evalue=2e-28,
Organism=Homo sapiens, GI6006001, Length=182, Percent_Identity=37.9120879120879, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI41406084, Length=186, Percent_Identity=40.3225806451613, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI33186887, Length=173, Percent_Identity=38.150289017341, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=35.3591160220994, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=54.2857142857143, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788003, Length=168, Percent_Identity=43.452380952381, Blast_Score=152, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=49.0566037735849, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=47.7987421383648, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=46.2962962962963, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=43.6708860759494, Blast_Score=139, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17550320, Length=185, Percent_Identity=35.1351351351351, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=32.967032967033, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=41.0526315789474, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=50, Blast_Score=76, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=38.1578947368421, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=101, Percent_Identity=35.6435643564356, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=52.5316455696203, Blast_Score=187, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6322228, Length=158, Percent_Identity=51.8987341772152, Blast_Score=184, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=48.3870967741936, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656772, Length=162, Percent_Identity=47.5308641975309, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24656767, Length=162, Percent_Identity=47.5308641975309, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=48.125, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI85726443, Length=164, Percent_Identity=42.0731707317073, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18014; Mature: 17882

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKSSIYSFSARTLDGEPVSFERYNGKVMLIVNTASECGFTPQYAGLQKLHEQYAARGL
CCCCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCC
QVLGFPCNQFGKQEPGDAAQIGAFCEKNYGVTFQMFDKIDVNGSDAHPLFRFLKDEAPGV
EEEECCHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCE
LGLEAIKWNFTKFLVDRDGKVVKRYAPTTKPETITDDIEALL
EEHHHHHHHHEEEEECCCCCEEEECCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
ADKSSIYSFSARTLDGEPVSFERYNGKVMLIVNTASECGFTPQYAGLQKLHEQYAARGL
CCCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCC
QVLGFPCNQFGKQEPGDAAQIGAFCEKNYGVTFQMFDKIDVNGSDAHPLFRFLKDEAPGV
EEEECCHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCE
LGLEAIKWNFTKFLVDRDGKVVKRYAPTTKPETITDDIEALL
EEHHHHHHHHEEEEECCCCCEEEECCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]