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The map label for this gene is plsC [H]

Identifier: 18310400

GI number: 18310400

Start: 1672370

End: 1673098

Strand: Direct

Name: plsC [H]

Synonym: CPE1418

Alternate gene names: 18310400

Gene position: 1672370-1673098 (Clockwise)

Preceding gene: 18310392

Following gene: 18310403

Centisome position: 55.17

GC content: 29.9

Gene sequence:

>729_bases
ATGTTTAGATCTATATATTGGTATGGAAAAGGATATGCCTGGACATTAATAAAATCCTTATCTGATATAAAAAAAATAAA
TAAAATGGAAGAGGAAGGCAAGCTTGAGGAAAGAGATGAATACATATATCAATGCAGTAGAAGAATAGCTCATACTTTTC
TTAAGGATGCTGGAATAGAAGTTAATGTTGAAGGTTTAGAGAATATTCCTGATGGACCTGTTCTTTTTGTTTGTAACCAT
CAAAGTAATATGGATATTCCTGTAATCATGTACTCTATTGATAGACCAAAGGGATTCATAGCAAAAAAAGAACTTGAAAA
AATGCCTATATTAAAAGATTGGATAATACTTTCAAAGGCTATATTTATTGACAGGGAACATCCTAAAAAAGCTATGGCAG
GTATTATACAAGGAATTAAACAATTAAAAGAAGGATATTCAATGGTTGTTTTTCCTGAAGGAACAAGAAGTCAATGTAGT
AAAATGGGAGAATTTAAAGCTGGTAGTTTTAAATTAGCTACTAAACCAAAGGTTCCTATAGTTCCTCTTACAATTGATGG
AACATATAAAATAATGGAAGGAAATCATTATTTCATAAAACCTGGTAAAGTAAATCTTTATATTCATCCACCAGTTTACA
CTGATAAACTTACAAAGGAAGAAATTACAGAGCTTCCTGAAAAAGTTGAAAATATAGTTAGAAGTAAACTTCCTAATGAA
GGAAGATAA

Upstream 100 bases:

>100_bases
TTTTTATTATTGCTCTCCACAAAATAAATTCCATATTTGATATTTTTTAAAAACTGTTATAATATTACTTAGTACTAGTA
ATATTAAAGGGGCGAAATAT

Downstream 100 bases:

>100_bases
AAAAATCCATGAGTAAATTTTACTCATGGATTTTTTATTTATATTAATTTAAAACAGTTCCTTCTAATTCTGCACTCTCT
TCACTTAAAGCTTTTTCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MFRSIYWYGKGYAWTLIKSLSDIKKINKMEEEGKLEERDEYIYQCSRRIAHTFLKDAGIEVNVEGLENIPDGPVLFVCNH
QSNMDIPVIMYSIDRPKGFIAKKELEKMPILKDWIILSKAIFIDREHPKKAMAGIIQGIKQLKEGYSMVVFPEGTRSQCS
KMGEFKAGSFKLATKPKVPIVPLTIDGTYKIMEGNHYFIKPGKVNLYIHPPVYTDKLTKEEITELPEKVENIVRSKLPNE
GR

Sequences:

>Translated_242_residues
MFRSIYWYGKGYAWTLIKSLSDIKKINKMEEEGKLEERDEYIYQCSRRIAHTFLKDAGIEVNVEGLENIPDGPVLFVCNH
QSNMDIPVIMYSIDRPKGFIAKKELEKMPILKDWIILSKAIFIDREHPKKAMAGIIQGIKQLKEGYSMVVFPEGTRSQCS
KMGEFKAGSFKLATKPKVPIVPLTIDGTYKIMEGNHYFIKPGKVNLYIHPPVYTDKLTKEEITELPEKVENIVRSKLPNE
GR
>Mature_242_residues
MFRSIYWYGKGYAWTLIKSLSDIKKINKMEEEGKLEERDEYIYQCSRRIAHTFLKDAGIEVNVEGLENIPDGPVLFVCNH
QSNMDIPVIMYSIDRPKGFIAKKELEKMPILKDWIILSKAIFIDREHPKKAMAGIIQGIKQLKEGYSMVVFPEGTRSQCS
KMGEFKAGSFKLATKPKVPIVPLTIDGTYKIMEGNHYFIKPGKVNLYIHPPVYTDKLTKEEITELPEKVENIVRSKLPNE
GR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=193, Percent_Identity=31.6062176165803, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI15100175, Length=193, Percent_Identity=31.6062176165803, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI6041665, Length=175, Percent_Identity=28, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789395, Length=167, Percent_Identity=28.1437125748503, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=193, Percent_Identity=30.0518134715026, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=191, Percent_Identity=34.5549738219895, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281364648, Length=206, Percent_Identity=29.6116504854369, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582856, Length=206, Percent_Identity=29.6116504854369, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582854, Length=206, Percent_Identity=29.6116504854369, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641614, Length=180, Percent_Identity=29.4444444444444, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641612, Length=180, Percent_Identity=29.4444444444444, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27830; Mature: 27830

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSIYWYGKGYAWTLIKSLSDIKKINKMEEEGKLEERDEYIYQCSRRIAHTFLKDAGIE
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCE
VNVEGLENIPDGPVLFVCNHQSNMDIPVIMYSIDRPKGFIAKKELEKMPILKDWIILSKA
EEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHH
IFIDREHPKKAMAGIIQGIKQLKEGYSMVVFPEGTRSQCSKMGEFKAGSFKLATKPKVPI
HEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCEEEECCCCCCE
VPLTIDGTYKIMEGNHYFIKPGKVNLYIHPPVYTDKLTKEEITELPEKVENIVRSKLPNE
EEEEECCEEEEEECCEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GR
CC
>Mature Secondary Structure
MFRSIYWYGKGYAWTLIKSLSDIKKINKMEEEGKLEERDEYIYQCSRRIAHTFLKDAGIE
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCE
VNVEGLENIPDGPVLFVCNHQSNMDIPVIMYSIDRPKGFIAKKELEKMPILKDWIILSKA
EEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHH
IFIDREHPKKAMAGIIQGIKQLKEGYSMVVFPEGTRSQCSKMGEFKAGSFKLATKPKVPI
HEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCEEEECCCCCCE
VPLTIDGTYKIMEGNHYFIKPGKVNLYIHPPVYTDKLTKEEITELPEKVENIVRSKLPNE
EEEEECCEEEEEECCEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]