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The map label for this gene is fabZ

Identifier: 170749837

GI number: 170749837

Start: 3650829

End: 3651305

Strand: Reverse

Name: fabZ

Synonym: Mrad2831_3437

Alternate gene names: 170749837

Gene position: 3651305-3650829 (Counterclockwise)

Preceding gene: 170749838

Following gene: 170749836

Centisome position: 60.08

GC content: 66.67

Gene sequence:

>477_bases
ATGAGTGAGGCGGCGCGCGAGACCGGCACCGAGCTGGGCACAGCCGACATCCAGACGCTGCTGGAGCTGCTGCCGCACCG
CTACCCGTTCCTGATGGTGGACCGCATCGTCGAGATCGACCGGGACGAATCCTGCGTCGGCATCAAGAACGTCACGGCCA
ACGAGCCGCAGTTCATGGGCCATTTCCCCGACATGCCGGTCTTCCCGGGCGTGCTCCTGATCGAGGGCATGGCGCAGACG
GCGGGCGCCATCTGCTGCCGCCACATCCGTGCGGACGGGCGGAACACCAAGCAGGTGTTCTTCATGACCATCGACAAGTG
CAAGTTCCGCAAGCCCGTCACCCCCGGCGACCAGGTGCGCTTCCACATGACGAAGCTGAACCAGCGCCGGACCATGTGGT
GGTTCCGCGGCGAGGCCCGGGTCGACGGCACGCTGGTCGCCGAGGCCGAGATCAGCGCCATGCTGGTGACGGAGTGA

Upstream 100 bases:

>100_bases
CCTTGCGCTTCCGGCGATTTCTTCCGAAGAGGGCGGTCGGCGCGCCGGAGGCGGCCGGATTGCGGGCCGCCGAAGGCGGC
AAGTCGAGGTGCGGATTTCG

Downstream 100 bases:

>100_bases
CCGCGCCCGCCATCCACCCGAGCGCCGTGATCGAGTCCGGCGCCCGGATCGGCGACGGGGCGCGGATCGGCCCCTTCTGC
CATGTCGGGCCCGAGGTCGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSEAARETGTELGTADIQTLLELLPHRYPFLMVDRIVEIDRDESCVGIKNVTANEPQFMGHFPDMPVFPGVLLIEGMAQT
AGAICCRHIRADGRNTKQVFFMTIDKCKFRKPVTPGDQVRFHMTKLNQRRTMWWFRGEARVDGTLVAEAEISAMLVTE

Sequences:

>Translated_158_residues
MSEAARETGTELGTADIQTLLELLPHRYPFLMVDRIVEIDRDESCVGIKNVTANEPQFMGHFPDMPVFPGVLLIEGMAQT
AGAICCRHIRADGRNTKQVFFMTIDKCKFRKPVTPGDQVRFHMTKLNQRRTMWWFRGEARVDGTLVAEAEISAMLVTE
>Mature_157_residues
SEAARETGTELGTADIQTLLELLPHRYPFLMVDRIVEIDRDESCVGIKNVTANEPQFMGHFPDMPVFPGVLLIEGMAQTA
GAICCRHIRADGRNTKQVFFMTIDKCKFRKPVTPGDQVRFHMTKLNQRRTMWWFRGEARVDGTLVAEAEISAMLVTE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=42.8571428571429, Blast_Score=126, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_METRJ (B1LTP5)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756097.1
- ProteinModelPortal:   B1LTP5
- SMR:   B1LTP5
- GeneID:   6139485
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3437
- HOGENOM:   HBG433282
- OMA:   ILQANIQ
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17916; Mature: 17785

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 61-61

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAARETGTELGTADIQTLLELLPHRYPFLMVDRIVEIDRDESCVGIKNVTANEPQFMG
CCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
HFPDMPVFPGVLLIEGMAQTAGAICCRHIRADGRNTKQVFFMTIDKCKFRKPVTPGDQVR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEE
FHMTKLNQRRTMWWFRGEARVDGTLVAEAEISAMLVTE
EEEECCCCCCEEEEECCCCCCCCEEEEECCEEEEEECC
>Mature Secondary Structure 
SEAARETGTELGTADIQTLLELLPHRYPFLMVDRIVEIDRDESCVGIKNVTANEPQFMG
CCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
HFPDMPVFPGVLLIEGMAQTAGAICCRHIRADGRNTKQVFFMTIDKCKFRKPVTPGDQVR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEE
FHMTKLNQRRTMWWFRGEARVDGTLVAEAEISAMLVTE
EEEECCCCCCEEEEECCCCCCCCEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA