Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 158317840

GI number: 158317840

Start: 7423208

End: 7424314

Strand: Reverse

Name: add [H]

Synonym: Franean1_6098

Alternate gene names: 158317840

Gene position: 7424314-7423208 (Counterclockwise)

Preceding gene: 158317841

Following gene: 158317839

Centisome position: 82.66

GC content: 75.25

Gene sequence:

>1107_bases
GTGGGTAGCGGGCCGAAGATCGAGCTGCACGTCCACCTCGAGGGGACGGTGCGGCCGGAGATGCTGCTCGCGATGGCGCG
CCGCAACAACGAGGCGCTGCCGGCCCGCACCGTCGAGGGCGTAGCCGAGCTGTACCGCTTCCGCGACTTCGACCACTTCC
TCAAGGTCTGGGTGCTCACGACGCAGGTCATGCGCACGGCCGACGACTTCCGCGAGATCGTCGTCGACTACGCGGGACGG
GCCGCCGCGCAGGGCGCCGTCTACCTCGAAGGCATCTTCTCGCCGTGGTTCCGGGTGAACCGGGGCGTGCCCTGGCAGGA
GATCTTCACCGGCTACGCCGAGGGTGCCGTCGAGGCCCGCGAGCGCTTCGGGGTCGAGGTACGGCTGACCCCGGACATCG
ACCGGGTGCTGCCACCCGAGGTCGCGATGGACGTCGTCGGCTGGGCAGCCCGGTTCACCGACCGCGGTGTCGTCGGGATC
GGGCTCGGCGGGCCCGAGGTGGGCCATCCGCCGGAGCCGTACGCGCCGGTCTTCGCCGCCGCCGCGGACGCCGGCCTGCC
CGCCGTCCCGCACGCGGGGGAGACGGCCGGCGCCGAGTCGGTGCGCGGCGCGCTGCACGCGCTGGGGGCGAGGCGGATCC
GGCACGGCGTGCGGGCCCTCGAGGACCCCGAGCTCGTCGCCGAGCTGGTAGAGCGGGGCATCGTGCTGGACGTCTGCCCG
ACGTCGAACCTGCGGACGGGTGTCGTCACCGACCTGGCGGCGCACCCGCTGCCCGAGCTGCTCGCGGCCGGGCTGCGCTG
CTCGCTGGCCACCGACGATCCGGCGATGTTCGGCACGGATCTCGAACGGGAGTACGCCGCCGCGGCGGGCCTCGGGGTGC
GCCTCGCCCGGCTCTACGAGGCCGGGGTTGCCGGCGCGCTGTGCGACGACCGGACCCGGTCCCGGCTGGCGGCGCTCGGG
GCCGGCACGGACTGGGACGCCGCCCAGGCCACGGCGCTCGCCGCCGAGGCTGCTGGGTCCGCGCTGGCCGGGTCCGCGCT
GGCCGGGTCTGACGCGGCTGGGTCCGCGACGGCGGGGTCCGTGGCCATGACGAACGCAGAGGGATGA

Upstream 100 bases:

>100_bases
CCTGAGCCACGACCAGCGCCACGAACCGAACGCTGTCCCGAAGGCCGTCCCGAACGCTGTGTCGATGTCCGCTGAGGCGG
TCAGGGGTGAGCCGGCCGCG

Downstream 100 bases:

>100_bases
GCCGGTGAGTCGAGCAGGTCTGGACAAGAAGCCCGACCAGGTGGCCGCGATGTTCGACCAGGTCGCGCGGCGGTACGACG
TGACGAACGCGGTGCTGTCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MGSGPKIELHVHLEGTVRPEMLLAMARRNNEALPARTVEGVAELYRFRDFDHFLKVWVLTTQVMRTADDFREIVVDYAGR
AAAQGAVYLEGIFSPWFRVNRGVPWQEIFTGYAEGAVEARERFGVEVRLTPDIDRVLPPEVAMDVVGWAARFTDRGVVGI
GLGGPEVGHPPEPYAPVFAAAADAGLPAVPHAGETAGAESVRGALHALGARRIRHGVRALEDPELVAELVERGIVLDVCP
TSNLRTGVVTDLAAHPLPELLAAGLRCSLATDDPAMFGTDLEREYAAAAGLGVRLARLYEAGVAGALCDDRTRSRLAALG
AGTDWDAAQATALAAEAAGSALAGSALAGSDAAGSATAGSVAMTNAEG

Sequences:

>Translated_368_residues
MGSGPKIELHVHLEGTVRPEMLLAMARRNNEALPARTVEGVAELYRFRDFDHFLKVWVLTTQVMRTADDFREIVVDYAGR
AAAQGAVYLEGIFSPWFRVNRGVPWQEIFTGYAEGAVEARERFGVEVRLTPDIDRVLPPEVAMDVVGWAARFTDRGVVGI
GLGGPEVGHPPEPYAPVFAAAADAGLPAVPHAGETAGAESVRGALHALGARRIRHGVRALEDPELVAELVERGIVLDVCP
TSNLRTGVVTDLAAHPLPELLAAGLRCSLATDDPAMFGTDLEREYAAAAGLGVRLARLYEAGVAGALCDDRTRSRLAALG
AGTDWDAAQATALAAEAAGSALAGSALAGSDAAGSATAGSVAMTNAEG
>Mature_367_residues
GSGPKIELHVHLEGTVRPEMLLAMARRNNEALPARTVEGVAELYRFRDFDHFLKVWVLTTQVMRTADDFREIVVDYAGRA
AAQGAVYLEGIFSPWFRVNRGVPWQEIFTGYAEGAVEARERFGVEVRLTPDIDRVLPPEVAMDVVGWAARFTDRGVVGIG
LGGPEVGHPPEPYAPVFAAAADAGLPAVPHAGETAGAESVRGALHALGARRIRHGVRALEDPELVAELVERGIVLDVCPT
SNLRTGVVTDLAAHPLPELLAAGLRCSLATDDPAMFGTDLEREYAAAAGLGVRLARLYEAGVAGALCDDRTRSRLAALGA
GTDWDAAQATALAAEAAGSALAGSALAGSDAAGSATAGSVAMTNAEG

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI29029552, Length=168, Percent_Identity=34.5238095238095, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI29029550, Length=168, Percent_Identity=34.5238095238095, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787910, Length=307, Percent_Identity=32.8990228013029, Blast_Score=151, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17538512, Length=318, Percent_Identity=25.7861635220126, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565969, Length=318, Percent_Identity=25.7861635220126, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324188, Length=326, Percent_Identity=30.0613496932515, Blast_Score=162, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24645260, Length=292, Percent_Identity=29.1095890410959, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38563; Mature: 38432

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGPKIELHVHLEGTVRPEMLLAMARRNNEALPARTVEGVAELYRFRDFDHFLKVWVLT
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TQVMRTADDFREIVVDYAGRAAAQGAVYLEGIFSPWFRVNRGVPWQEIFTGYAEGAVEAR
HHHHHHHHHHHHHHHHHHCHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ERFGVEVRLTPDIDRVLPPEVAMDVVGWAARFTDRGVVGIGLGGPEVGHPPEPYAPVFAA
HHCCCEEEECCCHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHH
AADAGLPAVPHAGETAGAESVRGALHALGARRIRHGVRALEDPELVAELVERGIVLDVCP
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECC
TSNLRTGVVTDLAAHPLPELLAAGLRCSLATDDPAMFGTDLEREYAAAAGLGVRLARLYE
CCCCCCHHHHHHHHCCHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGVAGALCDDRTRSRLAALGAGTDWDAAQATALAAEAAGSALAGSALAGSDAAGSATAGS
HCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCC
VAMTNAEG
EEECCCCC
>Mature Secondary Structure 
GSGPKIELHVHLEGTVRPEMLLAMARRNNEALPARTVEGVAELYRFRDFDHFLKVWVLT
CCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TQVMRTADDFREIVVDYAGRAAAQGAVYLEGIFSPWFRVNRGVPWQEIFTGYAEGAVEAR
HHHHHHHHHHHHHHHHHHCHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ERFGVEVRLTPDIDRVLPPEVAMDVVGWAARFTDRGVVGIGLGGPEVGHPPEPYAPVFAA
HHCCCEEEECCCHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHH
AADAGLPAVPHAGETAGAESVRGALHALGARRIRHGVRALEDPELVAELVERGIVLDVCP
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECC
TSNLRTGVVTDLAAHPLPELLAAGLRCSLATDDPAMFGTDLEREYAAAAGLGVRLARLYE
CCCCCCHHHHHHHHCCHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGVAGALCDDRTRSRLAALGAGTDWDAAQATALAAEAAGSALAGSALAGSDAAGSATAGS
HCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCC
VAMTNAEG
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA