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The map label for this gene is pgm [C]

Identifier: 158317665

GI number: 158317665

Start: 7193241

End: 7195034

Strand: Reverse

Name: pgm [C]

Synonym: Franean1_5923

Alternate gene names: 158317665

Gene position: 7195034-7193241 (Counterclockwise)

Preceding gene: 158317667

Following gene: 158317663

Centisome position: 80.1

GC content: 76.64

Gene sequence:

>1794_bases
GTGACGACCGCCCGTGACGACTCGACACCGAACCAGGCCGGACGGGCCTCGGGCCGGAAGGAACCGGGCCGTCGGGCGGG
TGGGGCGTGCCGGCATTCTGGTGGAGCCATGACCGCCCCCGTCTGCGGGCTGCCCGAGCCGCTGCCGGCACGGGTCGCGG
CCTGGCTTGCTGCGGACCCGGACCCCGGCGACCGGGCCGAGCTCGCCCGGCTGGTGGCCGCGGGCGACACCCGCGAGCTC
ACCGAGCGTTTCACCGGACCGCTCGCCTTCGGCACCGCGGGGCTGCGCGGGCCGCTGCGGGCCGGGCCGGCCGGGATGAA
CACCGCCGTGGTGCGGCGGACCACCGCCGGCCTCGGCTCCTGGCTACGGCGCCGCGTGACCGGGCCGCCGGTGGTGGTGA
TCGGATACGACGCCCGCCGGCGCAGCGACCACTTCGCCCTCGACGCGGCCCGGGTGCTGGCCGGGCAGGGCGTCCGGGCG
CTGGTCCTCCCAGAGTCGGGGCCCACCCCGGTGCTGGCGTTCGCCGTCCGCCACCTGGACGCGGCGGCCGGAATAATGAT
CACGGCGAGTCACAATCCGGCGTCCGACAACGGCTACAAGGTCTATCTCGGCGGTTCCGTGGGTGAGGCGGGGCGGGGCG
CCCAGCTCGTCGCCCCGGCTGACACCGAGATCGAGCACGAGATCGCCGCGGTCGGCCCGGCCGCTGCGATCCCGCTCGCC
GACGGCTGGACCCGTCTCGACGCCTCGGTCGTCACCGCATACGTCGAGGGCGCGGTGCGCGCGGTCGACACCGCCGCGCC
GGTGGACGGGCCGCCACTGCGGATCGCCTATACGCCGCTGCACGGCGTCGGCGCCGACGTCCTGGCCGCGGTGTTCGCCC
GCGCCGGCCTGCCCGTCCCGGTGCCCGTTGCCGCCCAGCGAGCCCCGGATCCCGACTTCCCCACGGCGCCGTTCCCGAAC
CCGGAGGAGCCCGGGGTGCTCGACGCCGTGCTGGCCCTGGGCGAGCGGGTGGGCGCCGACCTGGTGCTCGCGAACGACCC
GGACGCCGACCGGTGCGCCGCGGCGGTCGGCGGCCGGGTGCTGACCGGGGATGAGATCGGGCTGCTGCTGGCCGACCACG
TCCTGCGGGCGCGGCCCGGACCGGTCGCGACGACCGTGGTCAGCTCCTCGGCCCTGGCGGAGCTCGCCCGCGACCACGGC
GTGCCCTGTGCCCAGACCCTGACCGGCTTCAAATGGATCATGCGTGCCGATCCCGGCCTCGTGTTCGGCTACGAGGAGGC
CCTCGGCTACGCCGTGGCCCCCGACCTGGTGCGGGACAAGGACGGCATCACCGCCGCGCTGGCCCTCGCGCGGGCCGCCC
AGCGCGAGAAACGCGCCGGGCGCACCCTGCTGGACGTCCTCGACGACCTGCACCGCCGCATCGGCGTGTTCGCCACCGGC
CAGGTGTCCGTCCGCCTCGACGATCTCGCGGCCGTCGCCGCGGCGATGCGCCGGCTGCGGACGTCCCCGCCCGACCGCGT
CGCCGGCCGTCCCGTGACCGCCGTCCGGGACCTGCTCACCGGCGCGGTGGACGGTCTCCCGCCCGCGGACGTCCTGATCT
TCGACCTGGACGGCGGAGCGCGGCTCGTAGCCCGGCCGAGCGGCACCGAACCGAAGCTCAAGATCTATCTGCAGGCCGTC
GCGGACCGTGCGGCCGTGGCGGCGATCGGCCCGGCCGCCGCGCGCCGCCGTGCCCAGACCCAGTTGGACGCGCTGCGCGA
CGCCGCCGCCGACCTGCTGGGCCGCGACCACTAG

Upstream 100 bases:

>100_bases
CAGTGGCCCGCCTAACAGCGGACCGCCTGCCCGTGCCCCGCTCCGCGGGAGACCGGATTCCTCCCCGGCCTGAAGGCCAG
GGCATCCTCCAGGAGCACTG

Downstream 100 bases:

>100_bases
TGCAGGCCGGCCACGAGCGCAGGTGCCGGCAGTGGGCATCGTGGCGTGGCTCGACGCTACCGCCGCGGCGGCCCGGGAGA
CGATGATGGGGGCGTGATCC

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MTTARDDSTPNQAGRASGRKEPGRRAGGACRHSGGAMTAPVCGLPEPLPARVAAWLAADPDPGDRAELARLVAAGDTREL
TERFTGPLAFGTAGLRGPLRAGPAGMNTAVVRRTTAGLGSWLRRRVTGPPVVVIGYDARRRSDHFALDAARVLAGQGVRA
LVLPESGPTPVLAFAVRHLDAAAGIMITASHNPASDNGYKVYLGGSVGEAGRGAQLVAPADTEIEHEIAAVGPAAAIPLA
DGWTRLDASVVTAYVEGAVRAVDTAAPVDGPPLRIAYTPLHGVGADVLAAVFARAGLPVPVPVAAQRAPDPDFPTAPFPN
PEEPGVLDAVLALGERVGADLVLANDPDADRCAAAVGGRVLTGDEIGLLLADHVLRARPGPVATTVVSSSALAELARDHG
VPCAQTLTGFKWIMRADPGLVFGYEEALGYAVAPDLVRDKDGITAALALARAAQREKRAGRTLLDVLDDLHRRIGVFATG
QVSVRLDDLAAVAAAMRRLRTSPPDRVAGRPVTAVRDLLTGAVDGLPPADVLIFDLDGGARLVARPSGTEPKLKIYLQAV
ADRAAVAAIGPAAARRRAQTQLDALRDAAADLLGRDH

Sequences:

>Translated_597_residues
MTTARDDSTPNQAGRASGRKEPGRRAGGACRHSGGAMTAPVCGLPEPLPARVAAWLAADPDPGDRAELARLVAAGDTREL
TERFTGPLAFGTAGLRGPLRAGPAGMNTAVVRRTTAGLGSWLRRRVTGPPVVVIGYDARRRSDHFALDAARVLAGQGVRA
LVLPESGPTPVLAFAVRHLDAAAGIMITASHNPASDNGYKVYLGGSVGEAGRGAQLVAPADTEIEHEIAAVGPAAAIPLA
DGWTRLDASVVTAYVEGAVRAVDTAAPVDGPPLRIAYTPLHGVGADVLAAVFARAGLPVPVPVAAQRAPDPDFPTAPFPN
PEEPGVLDAVLALGERVGADLVLANDPDADRCAAAVGGRVLTGDEIGLLLADHVLRARPGPVATTVVSSSALAELARDHG
VPCAQTLTGFKWIMRADPGLVFGYEEALGYAVAPDLVRDKDGITAALALARAAQREKRAGRTLLDVLDDLHRRIGVFATG
QVSVRLDDLAAVAAAMRRLRTSPPDRVAGRPVTAVRDLLTGAVDGLPPADVLIFDLDGGARLVARPSGTEPKLKIYLQAV
ADRAAVAAIGPAAARRRAQTQLDALRDAAADLLGRDH
>Mature_596_residues
TTARDDSTPNQAGRASGRKEPGRRAGGACRHSGGAMTAPVCGLPEPLPARVAAWLAADPDPGDRAELARLVAAGDTRELT
ERFTGPLAFGTAGLRGPLRAGPAGMNTAVVRRTTAGLGSWLRRRVTGPPVVVIGYDARRRSDHFALDAARVLAGQGVRAL
VLPESGPTPVLAFAVRHLDAAAGIMITASHNPASDNGYKVYLGGSVGEAGRGAQLVAPADTEIEHEIAAVGPAAAIPLAD
GWTRLDASVVTAYVEGAVRAVDTAAPVDGPPLRIAYTPLHGVGADVLAAVFARAGLPVPVPVAAQRAPDPDFPTAPFPNP
EEPGVLDAVLALGERVGADLVLANDPDADRCAAAVGGRVLTGDEIGLLLADHVLRARPGPVATTVVSSSALAELARDHGV
PCAQTLTGFKWIMRADPGLVFGYEEALGYAVAPDLVRDKDGITAALALARAAQREKRAGRTLLDVLDDLHRRIGVFATGQ
VSVRLDDLAAVAAAMRRLRTSPPDRVAGRPVTAVRDLLTGAVDGLPPADVLIFDLDGGARLVARPSGTEPKLKIYLQAVA
DRAAVAAIGPAAARRRAQTQLDALRDAAADLLGRDH

Specific function: This Enzyme Participates In Both The Breakdown And Synthesis Of Glucose. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=572, Percent_Identity=31.8181818181818, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI31377548, Length=572, Percent_Identity=30.9440559440559, Blast_Score=241, Evalue=2e-63,
Organism=Escherichia coli, GI1786904, Length=523, Percent_Identity=26.1950286806883, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788361, Length=300, Percent_Identity=29.6666666666667, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789566, Length=411, Percent_Identity=27.2506082725061, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993870, Length=564, Percent_Identity=32.8014184397163, Blast_Score=255, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI71993878, Length=330, Percent_Identity=35.7575757575758, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6323934, Length=603, Percent_Identity=32.0066334991708, Blast_Score=264, Evalue=3e-71,
Organism=Drosophila melanogaster, GI20129809, Length=591, Percent_Identity=31.6412859560068, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24651977, Length=546, Percent_Identity=31.8681318681319, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24653722, Length=578, Percent_Identity=29.4117647058824, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 61540; Mature: 61408

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTARDDSTPNQAGRASGRKEPGRRAGGACRHSGGAMTAPVCGLPEPLPARVAAWLAADP
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
DPGDRAELARLVAAGDTRELTERFTGPLAFGTAGLRGPLRAGPAGMNTAVVRRTTAGLGS
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WLRRRVTGPPVVVIGYDARRRSDHFALDAARVLAGQGVRALVLPESGPTPVLAFAVRHLD
HHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
AAAGIMITASHNPASDNGYKVYLGGSVGEAGRGAQLVAPADTEIEHEIAAVGPAAAIPLA
HHCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHCCCCC
DGWTRLDASVVTAYVEGAVRAVDTAAPVDGPPLRIAYTPLHGVGADVLAAVFARAGLPVP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
VPVAAQRAPDPDFPTAPFPNPEEPGVLDAVLALGERVGADLVLANDPDADRCAAAVGGRV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCEE
LTGDEIGLLLADHVLRARPGPVATTVVSSSALAELARDHGVPCAQTLTGFKWIMRADPGL
EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCE
VFGYEEALGYAVAPDLVRDKDGITAALALARAAQREKRAGRTLLDVLDDLHRRIGVFATG
EEEHHHHCCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEECC
QVSVRLDDLAAVAAAMRRLRTSPPDRVAGRPVTAVRDLLTGAVDGLPPADVLIFDLDGGA
EEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCC
RLVARPSGTEPKLKIYLQAVADRAAVAAIGPAAARRRAQTQLDALRDAAADLLGRDH
EEEECCCCCCCHHEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTARDDSTPNQAGRASGRKEPGRRAGGACRHSGGAMTAPVCGLPEPLPARVAAWLAADP
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
DPGDRAELARLVAAGDTRELTERFTGPLAFGTAGLRGPLRAGPAGMNTAVVRRTTAGLGS
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WLRRRVTGPPVVVIGYDARRRSDHFALDAARVLAGQGVRALVLPESGPTPVLAFAVRHLD
HHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
AAAGIMITASHNPASDNGYKVYLGGSVGEAGRGAQLVAPADTEIEHEIAAVGPAAAIPLA
HHCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHCCCCC
DGWTRLDASVVTAYVEGAVRAVDTAAPVDGPPLRIAYTPLHGVGADVLAAVFARAGLPVP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
VPVAAQRAPDPDFPTAPFPNPEEPGVLDAVLALGERVGADLVLANDPDADRCAAAVGGRV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCEE
LTGDEIGLLLADHVLRARPGPVATTVVSSSALAELARDHGVPCAQTLTGFKWIMRADPGL
EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCE
VFGYEEALGYAVAPDLVRDKDGITAALALARAAQREKRAGRTLLDVLDDLHRRIGVFATG
EEEHHHHCCCHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEECC
QVSVRLDDLAAVAAAMRRLRTSPPDRVAGRPVTAVRDLLTGAVDGLPPADVLIFDLDGGA
EEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCC
RLVARPSGTEPKLKIYLQAVADRAAVAAIGPAAARRRAQTQLDALRDAAADLLGRDH
EEEECCCCCCCHHEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]