| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is limC [H]
Identifier: 158316251
GI number: 158316251
Start: 5340390
End: 5341211
Strand: Reverse
Name: limC [H]
Synonym: Franean1_4476
Alternate gene names: 158316251
Gene position: 5341211-5340390 (Counterclockwise)
Preceding gene: 158316253
Following gene: 158316250
Centisome position: 59.47
GC content: 65.33
Gene sequence:
>822_bases GTGGCCAAAGTTCAGGGCAAGGTGGCATTCGTGACGGGCGCCGGGCGGGGGCTTGGAAGGAGCTTCGCTGCCCGGCTGGC CGAGGAGGGCGCGGACATCATCGCGACGGACGTCTGTTCACCTGTGTCGTCGGCGCCGTACGGAATGGCGAGTTCGTCGG ATCTTGACCAGACCGTGGCGGAGGTCCGGGCGCTTGGCCGACACGCGGTCGCGTTCGAGTCCGACGTCCGGGACGGGGAG TCGATTCAGGCGGGGCTGGCCAAGGCGGTCGTCGAACTCGGCCGCCTCGACATCGTGTGCGCGAACGCAGGTTTCATCTC CTACGGTGCCGCGGTCGATCTCGCCGAGACCGAGTGGAACGAGATGATCGATGTCCATGTGACTGGCGCCTGGAACACCT GCAAGGCTGCCGTGCCCTATCTGATTCGGTCCGGTGTGGGAGCATCCATAGTCTTCACCAGCTCCATGGCGGGTCTTCGT GCCCGCCCGGGCATCGGCCATTATGTCACGGCCAAACACGCGGTTGTCGGCCTGATGCGCACCTTCGCGATCGAACTGGC GCCGTTCGGCGTCCGGGTCAATTCAGTGCATCCGACGTCGACGAACACGCAGATGATTCAGAACAGCGCGACCCGTCAGG TGGCCGACGGAGACGGAGCGGACGGTTCGGTCGAGGAGCGCAGGAAGTCCGGCAGGCTCCTCGATGTGCCGTGGATCGAG GCGATCGACGTGGCGAACGCTGTCCTCTTCCTCAGCTCGGAGGATGCCCGCTACATCACCGGGGTGACGTTGCCCATCGA CGCGGGTGCCATGTTGGTCTGA
Upstream 100 bases:
>100_bases TCCTCCCTTCTTCGGGCGGCGGGTAGCGAATGCGTCGTTGTCCGACCAGGCGATTTTCCGCTGCTGGTTGTTCGCGTCCA GGGAAAAGGATTGGCTAGCC
Downstream 100 bases:
>100_bases CGCTATCGACGATGCACACATCTACCGACTATCCAGGGCTGGAGCTGCATGACGACCGACGGGCAACTGTCAGGAAAAGT CGCGCTCATCACCGGAGCCG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: (4R,6S)-carveol dehydrogenase; CDH; Carveol dehydrogenase [H]
Number of amino acids: Translated: 273; Mature: 272
Protein sequence:
>273_residues MAKVQGKVAFVTGAGRGLGRSFAARLAEEGADIIATDVCSPVSSAPYGMASSSDLDQTVAEVRALGRHAVAFESDVRDGE SIQAGLAKAVVELGRLDIVCANAGFISYGAAVDLAETEWNEMIDVHVTGAWNTCKAAVPYLIRSGVGASIVFTSSMAGLR ARPGIGHYVTAKHAVVGLMRTFAIELAPFGVRVNSVHPTSTNTQMIQNSATRQVADGDGADGSVEERRKSGRLLDVPWIE AIDVANAVLFLSSEDARYITGVTLPIDAGAMLV
Sequences:
>Translated_273_residues MAKVQGKVAFVTGAGRGLGRSFAARLAEEGADIIATDVCSPVSSAPYGMASSSDLDQTVAEVRALGRHAVAFESDVRDGE SIQAGLAKAVVELGRLDIVCANAGFISYGAAVDLAETEWNEMIDVHVTGAWNTCKAAVPYLIRSGVGASIVFTSSMAGLR ARPGIGHYVTAKHAVVGLMRTFAIELAPFGVRVNSVHPTSTNTQMIQNSATRQVADGDGADGSVEERRKSGRLLDVPWIE AIDVANAVLFLSSEDARYITGVTLPIDAGAMLV >Mature_272_residues AKVQGKVAFVTGAGRGLGRSFAARLAEEGADIIATDVCSPVSSAPYGMASSSDLDQTVAEVRALGRHAVAFESDVRDGES IQAGLAKAVVELGRLDIVCANAGFISYGAAVDLAETEWNEMIDVHVTGAWNTCKAAVPYLIRSGVGASIVFTSSMAGLRA RPGIGHYVTAKHAVVGLMRTFAIELAPFGVRVNSVHPTSTNTQMIQNSATRQVADGDGADGSVEERRKSGRLLDVPWIEA IDVANAVLFLSSEDARYITGVTLPIDAGAMLV
Specific function: Catalyzes the oxidation of carveol to carvone, with a strong stereoselectivity since it efficiently converts only the (6S)-stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better substrate. Displays a broad substrate specificity with a preference
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=264, Percent_Identity=33.7121212121212, Blast_Score=115, Evalue=6e-26, Organism=Homo sapiens, GI15277342, Length=284, Percent_Identity=30.9859154929577, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI126723750, Length=271, Percent_Identity=29.520295202952, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4504505, Length=205, Percent_Identity=30.2439024390244, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI31542939, Length=259, Percent_Identity=28.1853281853282, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI40254992, Length=271, Percent_Identity=29.1512915129151, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=26.3358778625954, Blast_Score=82, Evalue=8e-16, Organism=Homo sapiens, GI66933014, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI10190704, Length=275, Percent_Identity=26.5454545454545, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI142976729, Length=211, Percent_Identity=27.4881516587678, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI210032110, Length=212, Percent_Identity=26.8867924528302, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI40254986, Length=205, Percent_Identity=30.2439024390244, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=28.3505154639175, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI302344755, Length=105, Percent_Identity=38.0952380952381, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=23.1617647058824, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=214, Percent_Identity=26.1682242990654, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI223718074, Length=207, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=227, Percent_Identity=22.4669603524229, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI87082100, Length=275, Percent_Identity=30.9090909090909, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1789208, Length=269, Percent_Identity=28.6245353159851, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1787335, Length=272, Percent_Identity=31.25, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1788459, Length=269, Percent_Identity=28.996282527881, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1786812, Length=274, Percent_Identity=29.5620437956204, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI87082160, Length=275, Percent_Identity=26.1818181818182, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1790717, Length=268, Percent_Identity=26.4925373134328, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=25.7575757575758, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787905, Length=267, Percent_Identity=25.0936329588015, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1788891, Length=204, Percent_Identity=31.8627450980392, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI2367175, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=24.3445692883895, Blast_Score=65, Evalue=7e-12, Organism=Escherichia coli, GI1787526, Length=269, Percent_Identity=27.5092936802974, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=36.9668246445498, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17561402, Length=273, Percent_Identity=27.8388278388278, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=28.7878787878788, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=27.9245283018868, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=28.1481481481481, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI71994600, Length=270, Percent_Identity=27.037037037037, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562906, Length=284, Percent_Identity=27.8169014084507, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=288, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17531453, Length=287, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115534694, Length=266, Percent_Identity=28.1954887218045, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=204, Percent_Identity=28.4313725490196, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203117, Length=216, Percent_Identity=28.2407407407407, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71982365, Length=256, Percent_Identity=28.515625, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562910, Length=288, Percent_Identity=27.4305555555556, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203115, Length=213, Percent_Identity=28.169014084507, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=297, Percent_Identity=26.9360269360269, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17558628, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=212, Percent_Identity=26.8867924528302, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562904, Length=288, Percent_Identity=25.6944444444444, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17559104, Length=298, Percent_Identity=28.1879194630872, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562990, Length=285, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17560332, Length=289, Percent_Identity=26.9896193771626, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560150, Length=279, Percent_Identity=25.089605734767, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17560220, Length=284, Percent_Identity=27.8169014084507, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=33.9901477832512, Blast_Score=106, Evalue=4e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=268, Percent_Identity=27.2388059701493, Blast_Score=79, Evalue=1e-15, Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=30.9433962264151, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=36.8686868686869, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21357041, Length=272, Percent_Identity=28.6764705882353, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI23397609, Length=271, Percent_Identity=32.4723247232472, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI28571526, Length=273, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI24644339, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24643142, Length=268, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24639444, Length=267, Percent_Identity=26.2172284644195, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24640492, Length=237, Percent_Identity=27.8481012658228, Blast_Score=79, Evalue=5e-15, Organism=Drosophila melanogaster, GI21355631, Length=184, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21357673, Length=210, Percent_Identity=28.0952380952381, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17737361, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI281364892, Length=214, Percent_Identity=25.2336448598131, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28509; Mature: 28377
Theoretical pI: Translated: 5.11; Mature: 5.11
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKVQGKVAFVTGAGRGLGRSFAARLAEEGADIIATDVCSPVSSAPYGMASSSDLDQTVA CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCCHHHHHHH EVRALGRHAVAFESDVRDGESIQAGLAKAVVELGRLDIVCANAGFISYGAAVDLAETEWN HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEECCCEEEECCCCCC EMIDVHVTGAWNTCKAAVPYLIRSGVGASIVFTSSMAGLRARPGIGHYVTAKHAVVGLMR CEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHH TFAIELAPFGVRVNSVHPTSTNTQMIQNSATRQVADGDGADGSVEERRKSGRLLDVPWIE HHHHHHCCCCEEEECCCCCCCCHHHHHCCCHHEECCCCCCCCCHHHHHHCCCEECCCCHH AIDVANAVLFLSSEDARYITGVTLPIDAGAMLV HHHHCCEEEEEECCCCEEEEEEEEEECCCCCCC >Mature Secondary Structure AKVQGKVAFVTGAGRGLGRSFAARLAEEGADIIATDVCSPVSSAPYGMASSSDLDQTVA CCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCCHHHHHHH EVRALGRHAVAFESDVRDGESIQAGLAKAVVELGRLDIVCANAGFISYGAAVDLAETEWN HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEECCCEEEECCCCCC EMIDVHVTGAWNTCKAAVPYLIRSGVGASIVFTSSMAGLRARPGIGHYVTAKHAVVGLMR CEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHH TFAIELAPFGVRVNSVHPTSTNTQMIQNSATRQVADGDGADGSVEERRKSGRLLDVPWIE HHHHHHCCCCEEEECCCCCCCCHHHHHCCCHHEECCCCCCCCCHHHHHHCCCEECCCCHH AIDVANAVLFLSSEDARYITGVTLPIDAGAMLV HHHHCCEEEEEECCCCEEEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10473585 [H]