BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is fabG [H]

Identifier: 158316253

GI number: 158316253

Start: 5343548

End: 5344303

Strand: Reverse

Name: fabG [H]

Synonym: Franean1_4478

Alternate gene names: 158316253

Gene position: 5344303-5343548 (Counterclockwise)

Preceding gene: 158316254

Following gene: 158316251

Centisome position: 59.5

GC content: 67.86

Gene sequence:

>756_bases
ATGGACCTGAGCGGCAGGACGGCGGTGGTCGTCGGAGCGGCGAACGTGGTCGGGCGGGCCTGTGCGCTCCGGTTCGCCCT
GGCCGGCGCGCACGTTGTGGTGGCCGACCCCGCCGAAGGTGCGCTGGCCGAGACGGTCGAGGCGATCGCCGCAGTGGCCG
GGTCCGTGCAGTCCGCCGTCGTGGACATAACTGATCTGTCCCAGCTGGAGCAACTGTCCGCATCGCTGGCGGGCCGCTAC
ATCGGTACCGATATCCTGGTGACGGCGCACTTTGCGATCGACCGGGGTTCCATTGAATTCTCCGCGGTCGAGACGTGGCG
CGAGGTCCTCGAGACCAACCTGTTGGGGCCGCTGGTATCGGCCAAAGCCTTCCTGCCCGCCTTGCGTCACTCGGAGCACG
CGGCGATCGTGCACATCGGCTCGATCGACGGGCTCCTCGGTAACCCGCAGGTCCCGTCGTACTCCGCCGCCAAGGCGGGC
ATGGTGGCACTCACCCGGGTGATGGCGCACGAGTTCGGGAAGTACGGCATCCGGGTCAACTGCGTGGCGCGTGCCGCGGT
GGACGACCCGTCCCAGGGCAGCGGGACCAGCCTCATGGAGAAAGTTCTTGACAGTACCGTCCTCAGACGTGCCGCGGCGC
CTGACGAAATCGCACAGGTGGTCGCATTTCTTTCGTCTGATGCCGCGGCGTACGTGACTGGTGCCGTTATCCCGGTGGAC
GGCGGGCGGGTGGGGCTGACACTGGGGACGGCCTGA

Upstream 100 bases:

>100_bases
GTGGGCTGCCCGGCGCGCCCGGAGATCGGTACTGGCCACAGTCACTGCTGCGCCGTGAGGGTCATCGCGCGGGAGCAGTC
GGACGGGGAGGTGCGTGCGG

Downstream 100 bases:

>100_bases
GCCTGCCGCCCCCGTCAGTCGTCGACCGCCGTGATCCTGGCGGCCTGCCGGGCAACCTCAGGGAAATATCTGCTCGCCGG
TGCGCAGGCTGCGGACAAGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY
IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG
MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD
GGRVGLTLGTA

Sequences:

>Translated_251_residues
MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY
IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG
MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD
GGRVGLTLGTA
>Mature_251_residues
MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAVVDITDLSQLEQLSASLAGRY
IGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVSAKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAG
MVALTRVMAHEFGKYGIRVNCVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD
GGRVGLTLGTA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.1960784313725, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=29.4354838709677, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=31.6666666666667, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=32.7956989247312, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.4110671936759, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=30.241935483871, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.3643724696356, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.1746031746032, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=26.8774703557312, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=30, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=26.953125, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=31.9672131147541, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=33.8461538461538, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=28.2258064516129, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=29.368029739777, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=24.7967479674797, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=26.9387755102041, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.125, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=25.6, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.8389513108614, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.9850746268657, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.9625468164794, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=25.6809338521401, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.3764258555133, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=254, Percent_Identity=25.9842519685039, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=29.8449612403101, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=27.710843373494, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=28.0487804878049, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=26.8292682926829, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=27.4900398406374, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357673, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=27.0491803278689, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25610; Mature: 25610

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAV
CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VDITDLSQLEQLSASLAGRYIGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVS
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHH
AKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAGMVALTRVMAHEFGKYGIRVN
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
CVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEHEEEEEEEC
GGRVGLTLGTA
CCEEEEEECCC
>Mature Secondary Structure
MDLSGRTAVVVGAANVVGRACALRFALAGAHVVVADPAEGALAETVEAIAAVAGSVQSAV
CCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VDITDLSQLEQLSASLAGRYIGTDILVTAHFAIDRGSIEFSAVETWREVLETNLLGPLVS
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHH
AKAFLPALRHSEHAAIVHIGSIDGLLGNPQVPSYSAAKAGMVALTRVMAHEFGKYGIRVN
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
CVARAAVDDPSQGSGTSLMEKVLDSTVLRRAAAPDEIAQVVAFLSSDAAAYVTGAVIPVD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEHEEEEEEEC
GGRVGLTLGTA
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]