BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is limC [H]

Identifier: 158316250

GI number: 158316250

Start: 5339499

End: 5340341

Strand: Reverse

Name: limC [H]

Synonym: Franean1_4475

Alternate gene names: 158316250

Gene position: 5340341-5339499 (Counterclockwise)

Preceding gene: 158316251

Following gene: 158316249

Centisome position: 59.46

GC content: 63.94

Gene sequence:

>843_bases
ATGACGACCGACGGGCAACTGTCAGGAAAAGTCGCGCTCATCACCGGAGCCGCGCGGGGGCAGGGGCGTTCCCACGCCAT
GCTCCTGGCTCAGGAAGGCGCGGACATCGTAGCTGTCGACATCGCGCGACAGATTGACTCGGTTCGGTATCCGCTGGCCA
CCGAGGATGAGCTCCGGGAGACGGCCGAAGCGGTCAGCGGGCTCGGCCGGCAGGTGATGTGCAAGGTGGCGGACGTTCGT
TCGTCCGAGCAGCTGTCCGCGGTCGTCGACAAGGCGATGGAACGCTTCGGGCATATTGACATCCTCTGTGTCAACGCCGG
TATCGCACAGTTCGCGAAAGCCGTGTGGGAGCTCACCGATCAGGAGTGGCGCGACATCCTCGACGTCAACCTCACCGGAG
CGTGGAAGACGGTGAAGGCAGTGGCCCCCGCCATGACGGGAACAGGGCGGGGCGGTTCGATCATCGTGACGGCTTCCTCC
ACCTCGCTCAAGCCGCGGCCCAACCTCGGCGCCTACAACACGTCGAAACATGGCCTCACAGGTCTCGTCGGCTCGCTCGC
GATCGAACTCGCACCCGCCGGCATCCGGGTGAACGCCATCGCCCCGGGCTCCGTGTCGACGCGCATGCTCCTGAACGAAA
ATGTTTTTCGGGTCACCCGACCCGATCTCGATGACCCGACCGAGAAGGATGCTTACGAACCGCTGCGCAAGCTCAACGTA
CTGCCCGTGCCCTGGGTCGAACCAGTGGACATCAGCAACGCTGTCCTCTGGCTTGCCTCCGAGAGTTCGCGTTATGTCAC
CGGTGTGATGCTTCCGGTCGATGCCGGCTCGGTCATCATCTGA

Upstream 100 bases:

>100_bases
CTACATCACCGGGGTGACGTTGCCCATCGACGCGGGTGCCATGTTGGTCTGACGCTATCGACGATGCACACATCTACCGA
CTATCCAGGGCTGGAGCTGC

Downstream 100 bases:

>100_bases
GTTCGGGAGTGTTCGATCAACGGCTCTGTAGAGCCGACTCTAAGTGACCTAAAGATTCTAAAGATTACTGAAGGCGGACG
GTGTTGGTAGGCAGGAATCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: (4R,6S)-carveol dehydrogenase; CDH; Carveol dehydrogenase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTTDGQLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRETAEAVSGLGRQVMCKVADVR
SSEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTDQEWRDILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASS
TSLKPRPNLGAYNTSKHGLTGLVGSLAIELAPAGIRVNAIAPGSVSTRMLLNENVFRVTRPDLDDPTEKDAYEPLRKLNV
LPVPWVEPVDISNAVLWLASESSRYVTGVMLPVDAGSVII

Sequences:

>Translated_280_residues
MTTDGQLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRETAEAVSGLGRQVMCKVADVR
SSEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTDQEWRDILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASS
TSLKPRPNLGAYNTSKHGLTGLVGSLAIELAPAGIRVNAIAPGSVSTRMLLNENVFRVTRPDLDDPTEKDAYEPLRKLNV
LPVPWVEPVDISNAVLWLASESSRYVTGVMLPVDAGSVII
>Mature_279_residues
TTDGQLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRETAEAVSGLGRQVMCKVADVRS
SEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTDQEWRDILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASST
SLKPRPNLGAYNTSKHGLTGLVGSLAIELAPAGIRVNAIAPGSVSTRMLLNENVFRVTRPDLDDPTEKDAYEPLRKLNVL
PVPWVEPVDISNAVLWLASESSRYVTGVMLPVDAGSVII

Specific function: Catalyzes the oxidation of carveol to carvone, with a strong stereoselectivity since it efficiently converts only the (6S)-stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better substrate. Displays a broad substrate specificity with a preference

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=280, Percent_Identity=34.2857142857143, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI126723750, Length=283, Percent_Identity=33.9222614840989, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=36, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=264, Percent_Identity=30.6818181818182, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI4504505, Length=224, Percent_Identity=31.25, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=33.8235294117647, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI19923817, Length=278, Percent_Identity=27.6978417266187, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=30.0724637681159, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=33.175355450237, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI40254992, Length=272, Percent_Identity=30.1470588235294, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=271, Percent_Identity=28.0442804428044, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=40.3669724770642, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4758504, Length=241, Percent_Identity=32.3651452282158, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI10190704, Length=271, Percent_Identity=26.5682656826568, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI142976729, Length=209, Percent_Identity=29.6650717703349, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI66933014, Length=272, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI224922801, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226371731, Length=211, Percent_Identity=26.0663507109005, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI83715985, Length=200, Percent_Identity=30, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI209862901, Length=231, Percent_Identity=29.4372294372294, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI19923983, Length=231, Percent_Identity=29.4372294372294, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI59889578, Length=206, Percent_Identity=25.2427184466019, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI25282469, Length=236, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=279, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789208, Length=271, Percent_Identity=34.6863468634686, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1788459, Length=273, Percent_Identity=32.2344322344322, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787335, Length=276, Percent_Identity=32.6086956521739, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787905, Length=273, Percent_Identity=30.4029304029304, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082160, Length=274, Percent_Identity=30.6569343065693, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786812, Length=275, Percent_Identity=28.7272727272727, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=273, Percent_Identity=30.4029304029304, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=25.7575757575758, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787526, Length=273, Percent_Identity=27.4725274725275, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367175, Length=270, Percent_Identity=27.037037037037, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788891, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367365, Length=272, Percent_Identity=26.1029411764706, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789057, Length=281, Percent_Identity=27.4021352313167, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786701, Length=217, Percent_Identity=26.2672811059908, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=276, Percent_Identity=31.5217391304348, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17562910, Length=288, Percent_Identity=30.2083333333333, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=270, Percent_Identity=28.1481481481481, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=278, Percent_Identity=29.136690647482, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=278, Percent_Identity=27.6978417266187, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=284, Percent_Identity=27.4647887323944, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=30.0448430493274, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=284, Percent_Identity=27.112676056338, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=286, Percent_Identity=28.6713286713287, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=277, Percent_Identity=29.6028880866426, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=286, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=283, Percent_Identity=27.5618374558304, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=287, Percent_Identity=27.1777003484321, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=283, Percent_Identity=27.208480565371, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=299, Percent_Identity=26.7558528428094, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=286, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=286, Percent_Identity=25.5244755244755, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=272, Percent_Identity=28.3088235294118, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=274, Percent_Identity=26.2773722627737, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=28.4132841328413, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=26.1682242990654, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=288, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=28.6384976525822, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=274, Percent_Identity=24.0875912408759, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=284, Percent_Identity=26.056338028169, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=207, Percent_Identity=28.5024154589372, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=284, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=214, Percent_Identity=28.0373831775701, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=214, Percent_Identity=28.0373831775701, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=27.0531400966184, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=286, Percent_Identity=23.7762237762238, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=280, Percent_Identity=26.4285714285714, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=204, Percent_Identity=26.9607843137255, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=286, Percent_Identity=25.1748251748252, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=276, Percent_Identity=27.8985507246377, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=217, Percent_Identity=33.6405529953917, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=252, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=28.3400809716599, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=209, Percent_Identity=29.1866028708134, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=30.7692307692308, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=268, Percent_Identity=28.3582089552239, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=27.6119402985075, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859837, Length=234, Percent_Identity=32.4786324786325, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=272, Percent_Identity=27.5735294117647, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355319, Length=264, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=279, Percent_Identity=30.1075268817204, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24644337, Length=276, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=28.9099526066351, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357673, Length=206, Percent_Identity=29.6116504854369, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648944, Length=216, Percent_Identity=26.8518518518519, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584752, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=28.2296650717703, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24581726, Length=209, Percent_Identity=30.1435406698565, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355631, Length=188, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640492, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29783; Mature: 29652

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDGQLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRE
CCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHCCCCCCHHHHHH
TAEAVSGLGRQVMCKVADVRSSEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTD
HHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCC
QEWRDILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASSTSLKPRPNLGAYNTSKHGLT
HHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
GLVGSLAIELAPAGIRVNAIAPGSVSTRMLLNENVFRVTRPDLDDPTEKDAYEPLRKLNV
HHHHHHHEEEECCCEEEEEECCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCC
LPVPWVEPVDISNAVLWLASESSRYVTGVMLPVDAGSVII
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEC
>Mature Secondary Structure 
TTDGQLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRE
CCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHCCCCCCHHHHHH
TAEAVSGLGRQVMCKVADVRSSEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTD
HHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCC
QEWRDILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASSTSLKPRPNLGAYNTSKHGLT
HHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
GLVGSLAIELAPAGIRVNAIAPGSVSTRMLLNENVFRVTRPDLDDPTEKDAYEPLRKLNV
HHHHHHHEEEECCCEEEEEECCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCC
LPVPWVEPVDISNAVLWLASESSRYVTGVMLPVDAGSVII
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10473585 [H]