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The map label for this gene is gltK [H]

Identifier: 157368268

GI number: 157368268

Start: 17877

End: 18617

Strand: Direct

Name: gltK [H]

Synonym: Spro_0019

Alternate gene names: 157368268

Gene position: 17877-18617 (Clockwise)

Preceding gene: 157368267

Following gene: 157368270

Centisome position: 0.33

GC content: 60.46

Gene sequence:

>741_bases
ATGGATTTCAGCGTCATTTACGACAATCTGGGTTATCTGCTGTGGGGCACCTGGCCGGACGGCCCGCTGGGCGGCGCAGC
GCTGACGTTGGCGATCAGCCTGATGGCCGGTGTGGCTTCGGCCATTATCGGCACGCTGTTGGGGGTGGCACTGGCGATGT
CACGCGGCGTAGCGGCCGGGTTACTGGCAGCGCTGCTGGGATTTTTCCGCGCCATCCCGGTGATCATGCTGATTTTCTGG
ACCTATTTCCTGTTACCGATCGTTTTTGGCGTGGATATTCCGGAAATCACCACCGTGGTTTGCGCCCTGGCGCTGATCGC
CTCGGCCTATCTGGCTCACGCGGTGAAGGCGGGGATCGCCGCCATCGGTCCGGGGCAGTGGCAGGCGGGTTTATCGCTAG
GATTGACTCGCTGGCAAACGCTGCGAATGATCGTGCTGCCGCAGGCGCTGCGCATGATGGTGCCTTCGTTTATCAACCAG
TGGATTTCGTTGATCAAGGACACTTCGCTGGCCTATATCGTCGGCGTCGGTGAGCTGACGTTCCTGGCGACCCAGGTCAA
CAACCGCAGCATGGTGTACCCGATGGAAGTCTTCCTGTTTATCGCCCTGGTGTACTTTGTGTTTTGTCTGGCGCTGGATC
TGCTGGCCAATGCGGTCAACCGCCGCTTTAGCCCGCAGACCCGGGCGTTGAAACGCTCATGGCGCTGGTGGCGCAATAAG
CCGCCGTTGCCGGCTAGCTAG

Upstream 100 bases:

>100_bases
GCGTTTGGCGTGGCGACGGTGCTGTACATCGCCATCATTGCGCTGTTGGAAGGCTGGGGTATGTGGCGACAGCAGCGTAA
ACCGCTGAGAGGGCACTAAG

Downstream 100 bases:

>100_bases
TCAACTGCCAGCCGCGTTCACGCCACAGCGCTGGTAATTGCGCCAAATCGTCGAATGCGGTGACCAGCGGATGGTCGATC
GGTTGGTTGTGCGGATCGGC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MDFSVIYDNLGYLLWGTWPDGPLGGAALTLAISLMAGVASAIIGTLLGVALAMSRGVAAGLLAALLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIAAIGPGQWQAGLSLGLTRWQTLRMIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVGELTFLATQVNNRSMVYPMEVFLFIALVYFVFCLALDLLANAVNRRFSPQTRALKRSWRWWRNK
PPLPAS

Sequences:

>Translated_246_residues
MDFSVIYDNLGYLLWGTWPDGPLGGAALTLAISLMAGVASAIIGTLLGVALAMSRGVAAGLLAALLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIAAIGPGQWQAGLSLGLTRWQTLRMIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVGELTFLATQVNNRSMVYPMEVFLFIALVYFVFCLALDLLANAVNRRFSPQTRALKRSWRWWRNK
PPLPAS
>Mature_246_residues
MDFSVIYDNLGYLLWGTWPDGPLGGAALTLAISLMAGVASAIIGTLLGVALAMSRGVAAGLLAALLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIAAIGPGQWQAGLSLGLTRWQTLRMIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVGELTFLATQVNNRSMVYPMEVFLFIALVYFVFCLALDLLANAVNRRFSPQTRALKRSWRWWRNK
PPLPAS

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=229, Percent_Identity=35.3711790393013, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=33.8028169014084, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=35.5140186915888, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=32.0388349514563, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI48994930, Length=140, Percent_Identity=35, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787087, Length=225, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786874, Length=229, Percent_Identity=26.2008733624454, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788646, Length=213, Percent_Identity=25.8215962441315, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788645, Length=219, Percent_Identity=26.4840182648402, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26833; Mature: 26833

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSVIYDNLGYLLWGTWPDGPLGGAALTLAISLMAGVASAIIGTLLGVALAMSRGVAAG
CCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLAALLGFFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGPGQWQAGLSLGLTRWQTLRMIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVGELT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHH
FLATQVNNRSMVYPMEVFLFIALVYFVFCLALDLLANAVNRRFSPQTRALKRSWRWWRNK
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
PPLPAS
CCCCCC
>Mature Secondary Structure
MDFSVIYDNLGYLLWGTWPDGPLGGAALTLAISLMAGVASAIIGTLLGVALAMSRGVAAG
CCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLAALLGFFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGPGQWQAGLSLGLTRWQTLRMIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVGELT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHH
FLATQVNNRSMVYPMEVFLFIALVYFVFCLALDLLANAVNRRFSPQTRALKRSWRWWRNK
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
PPLPAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]