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The map label for this gene is purP [H]

Identifier: 157368270

GI number: 157368270

Start: 19501

End: 20838

Strand: Direct

Name: purP [H]

Synonym: Spro_0021

Alternate gene names: 157368270

Gene position: 19501-20838 (Clockwise)

Preceding gene: 157368268

Following gene: 157368281

Centisome position: 0.36

GC content: 56.65

Gene sequence:

>1338_bases
ATGAACAAACAAGTCACTGGCCTTGACGTTGAGCAAGGCTTGCTTGGGCGCGTGTTTAAGCTCAAGCAACATGGCACCAC
GGCGCGTACGGAAACGATTGCCGGTATTACTACCTTCCTGACCATGGTGTATATCGTGTTCGTTAACCCTCAAATTCTGG
GTGCGGCGGGCATGGATACGCAGGCGGTGTTCGTAACCACCTGCCTGATTGCCGCTTTCGGCAGTATTTTTATGGGCCTG
CTGGCGAATCTGCCGGTGGCGCTGGCGCCGGCTATGGGTCTCAATGCGTTCTTCGCCTTTGTGGTCGTGGGCGCAATGGG
CATTTCATGGCAGGTCGGCATGGGTGCCATCTTCTGGGGCGCGGTCGGTTTGTTACTGCTGACCATTTTCCGCGTCCGCT
ACTGGATGATTGCCAATATTCCCATGAGCCTGCGGGTGGGGATCACCAGCGGTATCGGCCTGTTTATCGGCATGATGGGG
CTGAAAAATGCCGGTATCGTGGTGGCGAACCCGGATACGCTGGTGACCATCGGCAGTCTGACCTCGCATAACGTGCTGCT
GGGTGCGCTGGGCTTCTTTATTATTGCCGTGCTGTCCTCACGTAATTTCCATGCGGCGGTGCTGGTTTCCATCGTGGTAA
CCACCCTGATCGGCTGGGCGCTGGGCGATGTGAAATACGGCGGTGTGTTCTCCATGCCTCCGAACATTACTTCGGTGGTG
GGTCAGGTTGATTTGGCGGGGGCGCTGAACATTGGCCTGGCAGGGGTGATTTTCTCCTTTATGTTGGTGAATCTGTTCGA
CTCCTCCGGCACTTTGATTGGTGTGACCGATAAGGCGGGTCTGACCGACGCGACGGGTAAATTCCCGCGCATGAAGCAGG
CGCTGTACGTGGACAGCATCAGTTCGGTGGCCGGTTCGTTTGTCGGCACCTCTTCCGTTACCGCCTACATTGAAAGTTCC
GCCGGGGTTTCCGTCGGCGGCCGTACCGGTCTGACCGCGGTGGTTACCGGTATTCTGTTCCTGTTGGTGATTTTCCTGTC
GCCATTGGCAGGCATGGTTCCGGCTTATGCCGCTGCCGGCGCGTTGATCTACGTGGGCGTGCTGATGACATCCAGCCTGG
CGCGGGTGAAGTGGGATGACCTGACCGAAGCAGTACCGGCGTTTGTGACCGCGGTGATGATGCCGTTTAGTTTCTCAATT
ACCGAAGGTATCGCGCTCGGCTTTATTTCTTACTGCGTAATGAAGTTGGGTACCGGTCGCTGGCGTGAAATCAGCCCATG
CGTGGTAGTGGTAGCGCTGCTGTTTGTGCTGAAGATTGTTTTTGTCGACGGTCACTGA

Upstream 100 bases:

>100_bases
GTAAAGACGGCGAAAAAAAGCTGTGAGCGGCGTCAAAACCCTGACTTTTTGTTATAGGATAGCCGGCGACGGTCCATTCC
CTTCTTCGGAATTTCTGAAA

Downstream 100 bases:

>100_bases
TACGAAAGAACAGGGCCGACAAATATCGCCCCTCAGACTACTGACAAAGCCCGTTATTAGGGAGAGCGTGCCGAAGGGGT
CGTAGCGGCTTGCCCGCCGA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNKQVTGLDVEQGLLGRVFKLKQHGTTARTETIAGITTFLTMVYIVFVNPQILGAAGMDTQAVFVTTCLIAAFGSIFMGL
LANLPVALAPAMGLNAFFAFVVVGAMGISWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPMSLRVGITSGIGLFIGMMG
LKNAGIVVANPDTLVTIGSLTSHNVLLGALGFFIIAVLSSRNFHAAVLVSIVVTTLIGWALGDVKYGGVFSMPPNITSVV
GQVDLAGALNIGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLTDATGKFPRMKQALYVDSISSVAGSFVGTSSVTAYIESS
AGVSVGGRTGLTAVVTGILFLLVIFLSPLAGMVPAYAAAGALIYVGVLMTSSLARVKWDDLTEAVPAFVTAVMMPFSFSI
TEGIALGFISYCVMKLGTGRWREISPCVVVVALLFVLKIVFVDGH

Sequences:

>Translated_445_residues
MNKQVTGLDVEQGLLGRVFKLKQHGTTARTETIAGITTFLTMVYIVFVNPQILGAAGMDTQAVFVTTCLIAAFGSIFMGL
LANLPVALAPAMGLNAFFAFVVVGAMGISWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPMSLRVGITSGIGLFIGMMG
LKNAGIVVANPDTLVTIGSLTSHNVLLGALGFFIIAVLSSRNFHAAVLVSIVVTTLIGWALGDVKYGGVFSMPPNITSVV
GQVDLAGALNIGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLTDATGKFPRMKQALYVDSISSVAGSFVGTSSVTAYIESS
AGVSVGGRTGLTAVVTGILFLLVIFLSPLAGMVPAYAAAGALIYVGVLMTSSLARVKWDDLTEAVPAFVTAVMMPFSFSI
TEGIALGFISYCVMKLGTGRWREISPCVVVVALLFVLKIVFVDGH
>Mature_445_residues
MNKQVTGLDVEQGLLGRVFKLKQHGTTARTETIAGITTFLTMVYIVFVNPQILGAAGMDTQAVFVTTCLIAAFGSIFMGL
LANLPVALAPAMGLNAFFAFVVVGAMGISWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPMSLRVGITSGIGLFIGMMG
LKNAGIVVANPDTLVTIGSLTSHNVLLGALGFFIIAVLSSRNFHAAVLVSIVVTTLIGWALGDVKYGGVFSMPPNITSVV
GQVDLAGALNIGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLTDATGKFPRMKQALYVDSISSVAGSFVGTSSVTAYIESS
AGVSVGGRTGLTAVVTGILFLLVIFLSPLAGMVPAYAAAGALIYVGVLMTSSLARVKWDDLTEAVPAFVTAVMMPFSFSI
TEGIALGFISYCVMKLGTGRWREISPCVVVVALLFVLKIVFVDGH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=84.2696629213483, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=442, Percent_Identity=75.5656108597285, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=425, Percent_Identity=39.7647058823529, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI48994909, Length=428, Percent_Identity=38.3177570093458, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46455; Mature: 46455

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQVTGLDVEQGLLGRVFKLKQHGTTARTETIAGITTFLTMVYIVFVNPQILGAAGMDT
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCC
QAVFVTTCLIAAFGSIFMGLLANLPVALAPAMGLNAFFAFVVVGAMGISWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
AVGLLLLTIFRVRYWMIANIPMSLRVGITSGIGLFIGMMGLKNAGIVVANPDTLVTIGSL
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEECCC
TSHNVLLGALGFFIIAVLSSRNFHAAVLVSIVVTTLIGWALGDVKYGGVFSMPPNITSVV
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHH
GQVDLAGALNIGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLTDATGKFPRMKQALYVDSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
SSVAGSFVGTSSVTAYIESSAGVSVGGRTGLTAVVTGILFLLVIFLSPLAGMVPAYAAAG
HHHHHHHCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIYVGVLMTSSLARVKWDDLTEAVPAFVTAVMMPFSFSITEGIALGFISYCVMKLGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
WREISPCVVVVALLFVLKIVFVDGH
CCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKQVTGLDVEQGLLGRVFKLKQHGTTARTETIAGITTFLTMVYIVFVNPQILGAAGMDT
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCC
QAVFVTTCLIAAFGSIFMGLLANLPVALAPAMGLNAFFAFVVVGAMGISWQVGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
AVGLLLLTIFRVRYWMIANIPMSLRVGITSGIGLFIGMMGLKNAGIVVANPDTLVTIGSL
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEECCC
TSHNVLLGALGFFIIAVLSSRNFHAAVLVSIVVTTLIGWALGDVKYGGVFSMPPNITSVV
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHH
GQVDLAGALNIGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLTDATGKFPRMKQALYVDSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
SSVAGSFVGTSSVTAYIESSAGVSVGGRTGLTAVVTGILFLLVIFLSPLAGMVPAYAAAG
HHHHHHHCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIYVGVLMTSSLARVKWDDLTEAVPAFVTAVMMPFSFSITEGIALGFISYCVMKLGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
WREISPCVVVVALLFVLKIVFVDGH
CCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]