| Definition | Methanothermobacter thermautotrophicus str. Delta H chromosome, complete genome. |
|---|---|
| Accession | NC_000916 |
| Length | 1,751,377 |
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Identifier: 15678523
GI number: 15678523
Start: 434774
End: 436015
Strand: Direct
Name: Not Available
Synonym: MTH495
Alternate gene names: 15678523
Gene position: 434774-436015 (Clockwise)
Preceding gene: 15678522
Following gene: 15678524
Centisome position: 24.82
GC content: 48.47
Gene sequence:
>1242_bases ATGTCAGATGTTGTGTTGATTGACATATTTGCAGGTGCGGGGGGGCTTACTGAAGGTTTCCTTCGGAGTGATTATACATT CGTTTCACATATTGAGATGGACAGGGATGCGATTCAGACACTGGAGACAAGGGGACTCTATCATCACCTGCAGAGCGATG GTGACCCCGAGGATTACACCGAATACGTTAATGGTGAGATAGGACGTGAAGAACTATTCAGAAGATATCCTGACTTTGAC AGTGAACTGTACATGAACCTTGAACTCACAGAGGAAAACGTGGACAGGGTCATAGAGACCATCAGGTCAAAGATGAATGA TATGGGGACAGTTTCTGTTGATGGCATAATAGGTGGGCCTCCATGTCAGGCGTACTCATATGCTGGCAGATCCCGGAAGA ACATGGAAAAGGACAGGAGAAACTACCTCTACCTCCTGTACATTAAATTCCTGAAAGAATTCCAGCCGGAATTCTTTGTA TTCGAGAACGTCCCCGGGATGAAGTCAGCGCAAAGGGGCCACATACTATCTGATTTCCAGAGGAAGGTAACAGACCTGGA ATATAAACTTGACTTTGAAGTGCGTGATGCATATAACTTCGGGGTCCCTCAGAGGAGAAGGAGGATCATAGTCATCGGCC ACCGCATGGAAGATAAAAGGATACAGTTTGATGAGGAGAGGTATGCCGGTACAGTGAATGACATCCTATGTGATCTGCCC GCCCTTGAACCCGGCCAGGGCACAGACGGGCCCCAGGAATATAGATCCAGACCATCACGCCTCCTGAATGAGATGGGTAT AAGGACAGAGAATGATATTCTCCGACATCACCAGGCGCGAAGACACAACCCGCGGGACCGCGAAATTTACAGGAGAACAA TTGACGCATGGAACTCAGAGAGGAGAAGATTAAAATATACAGAACTTCCACCGGAACTCAGGACACACAGGAACACCAGG AGCTTCCTTGACCGTTACAAGGTGGTTGCAGGGGACCTCCCCTATTCCCATACCATTGTCGCGCATATATCAAAGGATGG ACACTACTACATCCACCCCGACAGAGAACAGGCCCGTTCTCTGACCGTAAGGGAAGCTGCAAGGATCCAGTCCTTCCCGG ATAACTACATATTTGAAGGATCCATGACCTCAAAGTACCGGCAGATAGGAAACGCCGTGCCTCCACTAATGTCTGAGAAG ATTGCCCGCAAACTTTATGAAATCTACAGGGGGGACCTCTGA
Upstream 100 bases:
>100_bases CACCCTCTGAGTTTAACCCATATGGGTGGACATAACAAAAAATAATTTAATGTGGTTAAGATAAATCATCAATGACAGGT AACCAGAGGCAGGTTCGGCG
Downstream 100 bases:
>100_bases TTTCTGAAAAGGATCTGCTGCTTGATATTCATACCAGAATCTGCGAATGGGGAAAAAAGAATTTAAGGAAATTTCCCTGG CGCGAAAGAAGAGATGACTA
Product: modification methyltransferase, cytosine-specific
Products: NA
Alternate protein names: M.DdeI; Cytosine-specific methyltransferase DdeI [H]
Number of amino acids: Translated: 413; Mature: 412
Protein sequence:
>413_residues MSDVVLIDIFAGAGGLTEGFLRSDYTFVSHIEMDRDAIQTLETRGLYHHLQSDGDPEDYTEYVNGEIGREELFRRYPDFD SELYMNLELTEENVDRVIETIRSKMNDMGTVSVDGIIGGPPCQAYSYAGRSRKNMEKDRRNYLYLLYIKFLKEFQPEFFV FENVPGMKSAQRGHILSDFQRKVTDLEYKLDFEVRDAYNFGVPQRRRRIIVIGHRMEDKRIQFDEERYAGTVNDILCDLP ALEPGQGTDGPQEYRSRPSRLLNEMGIRTENDILRHHQARRHNPRDREIYRRTIDAWNSERRRLKYTELPPELRTHRNTR SFLDRYKVVAGDLPYSHTIVAHISKDGHYYIHPDREQARSLTVREAARIQSFPDNYIFEGSMTSKYRQIGNAVPPLMSEK IARKLYEIYRGDL
Sequences:
>Translated_413_residues MSDVVLIDIFAGAGGLTEGFLRSDYTFVSHIEMDRDAIQTLETRGLYHHLQSDGDPEDYTEYVNGEIGREELFRRYPDFD SELYMNLELTEENVDRVIETIRSKMNDMGTVSVDGIIGGPPCQAYSYAGRSRKNMEKDRRNYLYLLYIKFLKEFQPEFFV FENVPGMKSAQRGHILSDFQRKVTDLEYKLDFEVRDAYNFGVPQRRRRIIVIGHRMEDKRIQFDEERYAGTVNDILCDLP ALEPGQGTDGPQEYRSRPSRLLNEMGIRTENDILRHHQARRHNPRDREIYRRTIDAWNSERRRLKYTELPPELRTHRNTR SFLDRYKVVAGDLPYSHTIVAHISKDGHYYIHPDREQARSLTVREAARIQSFPDNYIFEGSMTSKYRQIGNAVPPLMSEK IARKLYEIYRGDL >Mature_412_residues SDVVLIDIFAGAGGLTEGFLRSDYTFVSHIEMDRDAIQTLETRGLYHHLQSDGDPEDYTEYVNGEIGREELFRRYPDFDS ELYMNLELTEENVDRVIETIRSKMNDMGTVSVDGIIGGPPCQAYSYAGRSRKNMEKDRRNYLYLLYIKFLKEFQPEFFVF ENVPGMKSAQRGHILSDFQRKVTDLEYKLDFEVRDAYNFGVPQRRRRIIVIGHRMEDKRIQFDEERYAGTVNDILCDLPA LEPGQGTDGPQEYRSRPSRLLNEMGIRTENDILRHHQARRHNPRDREIYRRTIDAWNSERRRLKYTELPPELRTHRNTRS FLDRYKVVAGDLPYSHTIVAHISKDGHYYIHPDREQARSLTVREAARIQSFPDNYIFEGSMTSKYRQIGNAVPPLMSEKI ARKLYEIYRGDL
Specific function: This methylase recognizes the double-stranded sequence CTNAG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the DdeI endonuclease [H]
COG id: COG0270
COG function: function code L; Site-specific DNA methylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the C5-methyltransferase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018117 - InterPro: IPR001525 [H]
Pfam domain/function: PF00145 DNA_methylase [H]
EC number: =2.1.1.37 [H]
Molecular weight: Translated: 48577; Mature: 48446
Theoretical pI: Translated: 6.72; Mature: 6.72
Prosite motif: PS00094 C5_MTASE_1 ; PS00095 C5_MTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDVVLIDIFAGAGGLTEGFLRSDYTFVSHIEMDRDAIQTLETRGLYHHLQSDGDPEDYT CCCEEEEEEECCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH EYVNGEIGREELFRRYPDFDSELYMNLELTEENVDRVIETIRSKMNDMGTVSVDGIIGGP HHHCCCCCHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCEEECCCCCCC PCQAYSYAGRSRKNMEKDRRNYLYLLYIKFLKEFQPEFFVFENVPGMKSAQRGHILSDFQ CCHHHHHCCCCHHHHHHHHHCEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHH RKVTDLEYKLDFEVRDAYNFGVPQRRRRIIVIGHRMEDKRIQFDEERYAGTVNDILCDLP HHHHCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHHCCC ALEPGQGTDGPQEYRSRPSRLLNEMGIRTENDILRHHQARRHNPRDREIYRRTIDAWNSE CCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCH RRRLKYTELPPELRTHRNTRSFLDRYKVVAGDLPYSHTIVAHISKDGHYYIHPDREQARS HHCEECCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCHHHHHH LTVREAARIQSFPDNYIFEGSMTSKYRQIGNAVPPLMSEKIARKLYEIYRGDL HHHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure SDVVLIDIFAGAGGLTEGFLRSDYTFVSHIEMDRDAIQTLETRGLYHHLQSDGDPEDYT CCEEEEEEECCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH EYVNGEIGREELFRRYPDFDSELYMNLELTEENVDRVIETIRSKMNDMGTVSVDGIIGGP HHHCCCCCHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCEEECCCCCCC PCQAYSYAGRSRKNMEKDRRNYLYLLYIKFLKEFQPEFFVFENVPGMKSAQRGHILSDFQ CCHHHHHCCCCHHHHHHHHHCEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHH RKVTDLEYKLDFEVRDAYNFGVPQRRRRIIVIGHRMEDKRIQFDEERYAGTVNDILCDLP HHHHCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCHHHHHHCCC ALEPGQGTDGPQEYRSRPSRLLNEMGIRTENDILRHHQARRHNPRDREIYRRTIDAWNSE CCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCH RRRLKYTELPPELRTHRNTRSFLDRYKVVAGDLPYSHTIVAHISKDGHYYIHPDREQARS HHCEECCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCHHHHHH LTVREAARIQSFPDNYIFEGSMTSKYRQIGNAVPPLMSEKIARKLYEIYRGDL HHHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2823226 [H]