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The map label for this gene is ctpB [H]

Identifier: 150006871

GI number: 150006871

Start: 210426

End: 212159

Strand: Reverse

Name: ctpB [H]

Synonym: BDI_0205

Alternate gene names: 150006871

Gene position: 212159-210426 (Counterclockwise)

Preceding gene: 150006872

Following gene: 150006870

Centisome position: 4.41

GC content: 46.89

Gene sequence:

>1734_bases
ATGGATAAAAACAAAAGACTGACCGTATGGCTCCCGGTTATCATCGCGGCTAGTATCGCTTTAGGTATCTTTATTGGGAA
CCATTATTTATCTATCAGTCAAGGAAAAAAACGGTCCTACTCCAGCGGTAACAAGATAAATGCCATCTTGGACATTATCG
ACGAGCAATATGTTGACACGGTTAGCATGTCTAAGCTGGTAGAGAGTACGATCCCGAAAATATTCAGTGAATTAGACCCT
CACTCCGTATATATCCCCGCCGAAGACGCTTCCGTGGTGAATGAGGAGCTGGAAGGTTCTTTCAGTGGTATTGGCGTATC
ATTTAATATGCAAACCGATACGATCCTAGTGATCAGCGTAATTAGCGGTGGTCCCGCAGAGAAAGCAGGTTTACTGCCCT
TCGACCGGATCATCTCGATCAATGATTCTATTTTCTCCGGTAAGAAAAAGAACCAAGGAGAGATCATGAAGACACTCCGG
GGCGCAAAGAACAGTACGGTGAAACTAGGCGTACAGCGAGGAAATTCTCCTGAGTTGCTCTATTTTGACGTAACCCGTGG
AGATGTCCCTGTTAATTCGGTCGATGTTTCTTTCGAAGCGGCTAAAGGTATAGGTTACATCAAGGTTAGCAAATTCGCCC
GGAATACTTATAATGAGTTCATCACGGCGATCGCCAAGCTGAAACAAGCGGGCTGTACCTCTTTCGTGATCGACTTACGG
GGTAATACCGGCGGATATATGGATGCCGCTATCAATATGATTAACGAGTTTATGCCGGAAGGACGCTTGATCGTCTACAC
GGAAGGTAAGTCGTTCCCCCGTTCCGACGTATACGCAAACGGAACCGGAACTTGTAAAGACGCCCCGATCGTAGTATTGA
CCGATGAGATCTCGGCTTCCGCCAGTGAGATATTCTCCGGAGCGATCCAAGATAACGACCGTGGTACGATTATCGGACGA
AGAACGTATGGCAAGGGTCTGGTACAAACTCAAATGTCATTGAGCGACGGTTCAGAGATGCGATTGACCATCGCCCGTTA
TTACACGCCGTCCGGTCGCTGCATCCAGAAGAAATATGAGATGGGTAATACGGACGCTTACGACCAAGATATCTATAACC
GATATATGCACGGCGAGTTCGACTCGGCCGATAGCATCAAGATGGATGATTCCTTGAAATACCAGACCGTAGGCGGACGT
ACCGTATACGGCGGGGGCGGTATCATGCCAGATATCTTTATCCCTCGTGACACGAGCGGCGTTACCTCTTACTACTCAAA
TGTGGTAAATAGCGGCGTGCTTTACCTGTATGCGCTCGAGTACTCAGACCGCCATCGGGAGAAACTAGGCTCATTCAAGA
CTTGGGAGGAATTATATAATTACTTGCAGCAACAACCGCTCCTTTCCGACTTCGTGAACTTCGCCGCTACCAAGGGCATC
AAGAGACGTCCTACATTAATTAATATATCCGGCAAGTTAATCGAGAACCAATTGCAAGCGTATATCGTAAGGAATTTCTT
CGACGAGGCGGGCTTCTACCCCATTTTCCTAAAAGATGACGTTACCTTATTACGTGCGATCAAGATCTTGCAAGAGGGAA
AATCTGTGCCGAATGCGGAACTATTAAAACAATCAGCGAATGGAGACTTACACAGCCAAGCAGGCCCTACGAAAAGATAT
GGCCTCTCGAAAAAAAGAATATTCGAGGATTACCTTGTGCGAGCTATCGGATAA

Upstream 100 bases:

>100_bases
TATTCCGAGAATTATCGCATAGCGGACGGCTGCGAATTATTGAAGCGTGCCGGTATCATAGTAGATTATATAGATTTGAA
CGAATAAATAAAACGTTTTT

Downstream 100 bases:

>100_bases
GATCATGGACCGCTTGGAACAGACGGAACTGTTCCAAGCGGCTTCTTGCATCGCCCTTTATCACGCCATACCGGGAGAAG
TACAGACCGCCGGCTTTATC

Product: carboxy-terminal processing protease

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MDKNKRLTVWLPVIIAASIALGIFIGNHYLSISQGKKRSYSSGNKINAILDIIDEQYVDTVSMSKLVESTIPKIFSELDP
HSVYIPAEDASVVNEELEGSFSGIGVSFNMQTDTILVISVISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLR
GAKNSTVKLGVQRGNSPELLYFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYNEFITAIAKLKQAGCTSFVIDLR
GNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSDVYANGTGTCKDAPIVVLTDEISASASEIFSGAIQDNDRGTIIGR
RTYGKGLVQTQMSLSDGSEMRLTIARYYTPSGRCIQKKYEMGNTDAYDQDIYNRYMHGEFDSADSIKMDDSLKYQTVGGR
TVYGGGGIMPDIFIPRDTSGVTSYYSNVVNSGVLYLYALEYSDRHREKLGSFKTWEELYNYLQQQPLLSDFVNFAATKGI
KRRPTLINISGKLIENQLQAYIVRNFFDEAGFYPIFLKDDVTLLRAIKILQEGKSVPNAELLKQSANGDLHSQAGPTKRY
GLSKKRIFEDYLVRAIG

Sequences:

>Translated_577_residues
MDKNKRLTVWLPVIIAASIALGIFIGNHYLSISQGKKRSYSSGNKINAILDIIDEQYVDTVSMSKLVESTIPKIFSELDP
HSVYIPAEDASVVNEELEGSFSGIGVSFNMQTDTILVISVISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLR
GAKNSTVKLGVQRGNSPELLYFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYNEFITAIAKLKQAGCTSFVIDLR
GNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSDVYANGTGTCKDAPIVVLTDEISASASEIFSGAIQDNDRGTIIGR
RTYGKGLVQTQMSLSDGSEMRLTIARYYTPSGRCIQKKYEMGNTDAYDQDIYNRYMHGEFDSADSIKMDDSLKYQTVGGR
TVYGGGGIMPDIFIPRDTSGVTSYYSNVVNSGVLYLYALEYSDRHREKLGSFKTWEELYNYLQQQPLLSDFVNFAATKGI
KRRPTLINISGKLIENQLQAYIVRNFFDEAGFYPIFLKDDVTLLRAIKILQEGKSVPNAELLKQSANGDLHSQAGPTKRY
GLSKKRIFEDYLVRAIG
>Mature_577_residues
MDKNKRLTVWLPVIIAASIALGIFIGNHYLSISQGKKRSYSSGNKINAILDIIDEQYVDTVSMSKLVESTIPKIFSELDP
HSVYIPAEDASVVNEELEGSFSGIGVSFNMQTDTILVISVISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLR
GAKNSTVKLGVQRGNSPELLYFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYNEFITAIAKLKQAGCTSFVIDLR
GNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSDVYANGTGTCKDAPIVVLTDEISASASEIFSGAIQDNDRGTIIGR
RTYGKGLVQTQMSLSDGSEMRLTIARYYTPSGRCIQKKYEMGNTDAYDQDIYNRYMHGEFDSADSIKMDDSLKYQTVGGR
TVYGGGGIMPDIFIPRDTSGVTSYYSNVVNSGVLYLYALEYSDRHREKLGSFKTWEELYNYLQQQPLLSDFVNFAATKGI
KRRPTLINISGKLIENQLQAYIVRNFFDEAGFYPIFLKDDVTLLRAIKILQEGKSVPNAELLKQSANGDLHSQAGPTKRY
GLSKKRIFEDYLVRAIG

Specific function: Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Forespore intermembrane space. Note=Is expressed in both the mother cell and forespore compartments but that synthesis in the forespore is both necessary and sufficient for the proper timing of pro-sigma-K processing [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=332, Percent_Identity=27.1084337349398, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 63829; Mature: 63829

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNKRLTVWLPVIIAASIALGIFIGNHYLSISQGKKRSYSSGNKINAILDIIDEQYVDT
CCCCCEEEEEHHHHHHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
VSMSKLVESTIPKIFSELDPHSVYIPAEDASVVNEELEGSFSGIGVSFNMQTDTILVISV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEE
ISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLRGAKNSTVKLGVQRGNSPELL
ECCCCCCCCCCCCHHHEEEECCHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCEE
YFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYNEFITAIAKLKQAGCTSFVIDLR
EEEECCCCCCCCEEEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSDVYANGTGTCKDAPIVVLTDEISAS
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCEEEEECCCCCC
ASEIFSGAIQDNDRGTIIGRRTYGKGLVQTQMSLSDGSEMRLTIARYYTPSGRCIQKKYE
HHHHHHCCCCCCCCCEEEEECCCCCCHHEEEEECCCCCCEEEEEEEEECCCCCHHHHHHC
MGNTDAYDQDIYNRYMHGEFDSADSIKMDDSLKYQTVGGRTVYGGGGIMPDIFIPRDTSG
CCCCCCHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCEEEECCCCCCCCEEECCCCCH
VTSYYSNVVNSGVLYLYALEYSDRHREKLGSFKTWEELYNYLQQQPLLSDFVNFAATKGI
HHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KRRPTLINISGKLIENQLQAYIVRNFFDEAGFYPIFLKDDVTLLRAIKILQEGKSVPNAE
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCHH
LLKQSANGDLHSQAGPTKRYGLSKKRIFEDYLVRAIG
HHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKNKRLTVWLPVIIAASIALGIFIGNHYLSISQGKKRSYSSGNKINAILDIIDEQYVDT
CCCCCEEEEEHHHHHHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
VSMSKLVESTIPKIFSELDPHSVYIPAEDASVVNEELEGSFSGIGVSFNMQTDTILVISV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEE
ISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLRGAKNSTVKLGVQRGNSPELL
ECCCCCCCCCCCCHHHEEEECCHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCEE
YFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYNEFITAIAKLKQAGCTSFVIDLR
EEEECCCCCCCCEEEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSDVYANGTGTCKDAPIVVLTDEISAS
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCEEEEECCCCCC
ASEIFSGAIQDNDRGTIIGRRTYGKGLVQTQMSLSDGSEMRLTIARYYTPSGRCIQKKYE
HHHHHHCCCCCCCCCEEEEECCCCCCHHEEEEECCCCCCEEEEEEEEECCCCCHHHHHHC
MGNTDAYDQDIYNRYMHGEFDSADSIKMDDSLKYQTVGGRTVYGGGGIMPDIFIPRDTSG
CCCCCCHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCEEEECCCCCCCCEEECCCCCH
VTSYYSNVVNSGVLYLYALEYSDRHREKLGSFKTWEELYNYLQQQPLLSDFVNFAATKGI
HHHHHHHHHCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
KRRPTLINISGKLIENQLQAYIVRNFFDEAGFYPIFLKDDVTLLRAIKILQEGKSVPNAE
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCHH
LLKQSANGDLHSQAGPTKRYGLSKKRIFEDYLVRAIG
HHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9570401; 9384377 [H]