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The map label for this gene is comEB [H]

Identifier: 150006872

GI number: 150006872

Start: 212173

End: 212607

Strand: Reverse

Name: comEB [H]

Synonym: BDI_0206

Alternate gene names: 150006872

Gene position: 212607-212173 (Counterclockwise)

Preceding gene: 150006873

Following gene: 150006871

Centisome position: 4.42

GC content: 44.6

Gene sequence:

>435_bases
ATGTGCGAGAAAACAGAAAAACAGCACGAATTAGATAAACGTTACCTGCGAATGGCCGCTATCTGGGCCGAGAATTCGTA
CTGTAAACGACGCCAAGTGGGCGCATTATTAGTAAAAGATAAAATGATCATATCCGACGGATACAATGGAACACCCGCCG
GTTTTGAAAATGTTTGCGAAGACGAGAACAATGTCACCAAGCCTTATGTTCTACACGCGGAGGCTAACGCCATCACAAAA
GTGGCAGCCTCATCGAACAGCAGTAAAGGAGCGACCATTTATGTGACCTCCTCCCCTTGCATTGAATGCGCAAAATTAAT
CATACAATCCGGGATCAAGCGAGTGGTCTATTCCGAGAATTATCGCATAGCGGACGGCTGCGAATTATTGAAGCGTGCCG
GTATCATAGTAGATTATATAGATTTGAACGAATAA

Upstream 100 bases:

>100_bases
GTAATGGTATTAAGAAGTAATAATTTACCGGGCTTATCGCCCGGTAAATCTAAATAATCACTACCTTTGTGTCTGGATTA
AAAGACAAAAGAGTAAACAA

Downstream 100 bases:

>100_bases
ATAAAACGTTTTTATGGATAAAAACAAAAGACTGACCGTATGGCTCCCGGTTATCATCGCGGCTAGTATCGCTTTAGGTA
TCTTTATTGGGAACCATTAT

Product: deoxycytidylate deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMIISDGYNGTPAGFENVCEDENNVTKPYVLHAEANAITK
VAASSNSSKGATIYVTSSPCIECAKLIIQSGIKRVVYSENYRIADGCELLKRAGIIVDYIDLNE

Sequences:

>Translated_144_residues
MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMIISDGYNGTPAGFENVCEDENNVTKPYVLHAEANAITK
VAASSNSSKGATIYVTSSPCIECAKLIIQSGIKRVVYSENYRIADGCELLKRAGIIVDYIDLNE
>Mature_144_residues
MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMIISDGYNGTPAGFENVCEDENNVTKPYVLHAEANAITK
VAASSNSSKGATIYVTSSPCIECAKLIIQSGIKRVVYSENYRIADGCELLKRAGIIVDYIDLNE

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=133, Percent_Identity=37.593984962406, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI61742821, Length=133, Percent_Identity=37.593984962406, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557019, Length=120, Percent_Identity=38.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321938, Length=143, Percent_Identity=34.2657342657343, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 16042; Mature: 16042

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMIISDGYNGTPAGFENVCE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEEECEEEEECCCCCCCCCHHHHHC
DENNVTKPYVLHAEANAITKVAASSNSSKGATIYVTSSPCIECAKLIIQSGIKRVVYSEN
CCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
YRIADGCELLKRAGIIVDYIDLNE
CEEHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMIISDGYNGTPAGFENVCE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEEECEEEEECCCCCCCCCHHHHHC
DENNVTKPYVLHAEANAITKVAASSNSSKGATIYVTSSPCIECAKLIIQSGIKRVVYSEN
CCCCCCCCEEEEECCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
YRIADGCELLKRAGIIVDYIDLNE
CEEHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]