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The map label for this gene is cinA [C]

Identifier: 126695618

GI number: 126695618

Start: 256302

End: 257576

Strand: Reverse

Name: cinA [C]

Synonym: P9301_02801

Alternate gene names: 126695618

Gene position: 257576-256302 (Counterclockwise)

Preceding gene: 126695619

Following gene: 126695617

Centisome position: 15.69

GC content: 33.1

Gene sequence:

>1275_bases
ATGAGTCCTAACTCCAAGGGAGTTGAAATTCTTTCTATTGGAACAGAGCTACTCTTAGGAAATATCATAAATACAAATGC
TCAATGGATTTCTGAACAGTTATCTCAATTAGGCTTAAATCACTTTAGGCAATCAACTGTAGGTGATAATTGTGATCGAA
TTGTAAGAGTAATTCAAGAAATATCGAAAAGAAGTAATCTTCTAATTACAACTGGTGGCTTAGGACCCACCCCAGATGAC
TTAACTACTGAAGCAATAGCCAAATCTTTTAATGTAACTCTTTTTGAAAGACCGCACTTATGGGACGAAATTAAACAAAA
ATTGCCAAACTCAAAGCTCCATGAAGATTCCTCTAGCTTAAGGAAACAATGTTTTTTCCCAAAAAATGCTCAAATAATTA
ATAACCCTAGGGGCACTGCCCCAGGAATGATATGGGAACCAATAAAAGGATTTACTATTCTTACATTCCCTGGAGTACCT
AGTGAAATGAAAACTATGTGGGAAGAAACGGCGTATGATTTCATTCAAACCAAATTTTCAGATACTTATTCCTTTTTTTC
AAATACCCTTAAATTTGCAGGTATTGGAGAATCTAGTGTTGCAGAAAAAATTAACGATCTATTAAATCTTAAAAACCCGA
CAGTTGCTCCATATGCCAACTTAGGAGAAGTTAAACTCAGAATCACAGCCAGAGCAAAGAATGAAGTTGAAGCAAAGAAT
ATTATTAAACCAATAAAAGAAAAATTAAAACAAGAGTTTTCTAAATTTATTTTTGGAGAAGATAATGATACTCTTCCAAG
TATTTTAATAAAAGAATTAACCAAGAGGAAACAAACTATTGTTTTTGCTGAATCCTGTACCGGAGGCCTGTTATCTGCAT
CACTAACATCAATATCAGGCTCATCTCAAGTTTTTCAAGGTAGTATTGTTTCCTATAGTAATGAGCTAAAACATTTATTA
TTAGATATTTCTGAAGAAAAGCTTGCAAAATATGGAGCTGTTTCTGAAGAAGTTTGTGAGGCTATGGCAATTAATGTCAA
AAAGAAATTAAGAGCAGATTGGGCAATATCAATTAGTGGAATAGCTGGTCCTAACGGAGGCAGTCAAAATAAACCAGTTG
GACTTGTCTATATCTCAATTTCAGGACCGAATAATTATATAACTACTATAAAAAAACAATTTAATTCAACCCGAAATAGA
CTTGAAATTCAAACACTAAGTGTAAATGTGTGTTTAAACAGCCTCAGATTAATCCTATTATCGGATAGTAAGTAA

Upstream 100 bases:

>100_bases
ACCCAGACGATTCACTGATTGAAAGTCAATGTAAAGAAAGAGTATTAACCCTATGTAATCGTTTTCCTCTTTATGAAAGC
AAACTTGAAGCATCAATTAA

Downstream 100 bases:

>100_bases
CTTTTTTACAAATTGAGTAAAGATACCTTATTTGATAAAGTTTGGGATTTACACAAAGTTTCCAGTCTCCCTGGTGGCTC
AGATCAAATTTTTATTGGTC

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVRVIQEISKRSNLLITTGGLGPTPDD
LTTEAIAKSFNVTLFERPHLWDEIKQKLPNSKLHEDSSSLRKQCFFPKNAQIINNPRGTAPGMIWEPIKGFTILTFPGVP
SEMKTMWEETAYDFIQTKFSDTYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNEVEAKN
IIKPIKEKLKQEFSKFIFGEDNDTLPSILIKELTKRKQTIVFAESCTGGLLSASLTSISGSSQVFQGSIVSYSNELKHLL
LDISEEKLAKYGAVSEEVCEAMAINVKKKLRADWAISISGIAGPNGGSQNKPVGLVYISISGPNNYITTIKKQFNSTRNR
LEIQTLSVNVCLNSLRLILLSDSK

Sequences:

>Translated_424_residues
MSPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVRVIQEISKRSNLLITTGGLGPTPDD
LTTEAIAKSFNVTLFERPHLWDEIKQKLPNSKLHEDSSSLRKQCFFPKNAQIINNPRGTAPGMIWEPIKGFTILTFPGVP
SEMKTMWEETAYDFIQTKFSDTYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNEVEAKN
IIKPIKEKLKQEFSKFIFGEDNDTLPSILIKELTKRKQTIVFAESCTGGLLSASLTSISGSSQVFQGSIVSYSNELKHLL
LDISEEKLAKYGAVSEEVCEAMAINVKKKLRADWAISISGIAGPNGGSQNKPVGLVYISISGPNNYITTIKKQFNSTRNR
LEIQTLSVNVCLNSLRLILLSDSK
>Mature_423_residues
SPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVRVIQEISKRSNLLITTGGLGPTPDDL
TTEAIAKSFNVTLFERPHLWDEIKQKLPNSKLHEDSSSLRKQCFFPKNAQIINNPRGTAPGMIWEPIKGFTILTFPGVPS
EMKTMWEETAYDFIQTKFSDTYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNEVEAKNI
IKPIKEKLKQEFSKFIFGEDNDTLPSILIKELTKRKQTIVFAESCTGGLLSASLTSISGSSQVFQGSIVSYSNELKHLLL
DISEEKLAKYGAVSEEVCEAMAINVKKKLRADWAISISGIAGPNGGSQNKPVGLVYISISGPNNYITTIKKQFNSTRNRL
EIQTLSVNVCLNSLRLILLSDSK

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=291, Percent_Identity=32.6460481099656, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789052, Length=137, Percent_Identity=43.7956204379562, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787818, Length=129, Percent_Identity=34.1085271317829, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71993974, Length=279, Percent_Identity=26.5232974910394, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71993966, Length=279, Percent_Identity=26.5232974910394, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323832, Length=167, Percent_Identity=28.7425149700599, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_PROM0 (A3PAX8)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090504.1
- ProteinModelPortal:   A3PAX8
- SMR:   A3PAX8
- STRING:   A3PAX8
- GeneID:   4912777
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_02801
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK921788
- BioCyc:   PMAR167546:P9301ORF_0283-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 46878; Mature: 46747

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVRVIQE
CCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ISKRSNLLITTGGLGPTPDDLTTEAIAKSFNVTLFERPHLWDEIKQKLPNSKLHEDSSSL
HHHCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCCHHHH
RKQCFFPKNAQIINNPRGTAPGMIWEPIKGFTILTFPGVPSEMKTMWEETAYDFIQTKFS
HHHHCCCCCCEEECCCCCCCCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
DTYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNEVEAKN
HHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
IIKPIKEKLKQEFSKFIFGEDNDTLPSILIKELTKRKQTIVFAESCTGGLLSASLTSISG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCC
SSQVFQGSIVSYSNELKHLLLDISEEKLAKYGAVSEEVCEAMAINVKKKLRADWAISISG
CCHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
IAGPNGGSQNKPVGLVYISISGPNNYITTIKKQFNSTRNRLEIQTLSVNVCLNSLRLILL
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCHHHEEEEEEEEHHHHHCCEEEEEE
SDSK
ECCC
>Mature Secondary Structure 
SPNSKGVEILSIGTELLLGNIINTNAQWISEQLSQLGLNHFRQSTVGDNCDRIVRVIQE
CCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ISKRSNLLITTGGLGPTPDDLTTEAIAKSFNVTLFERPHLWDEIKQKLPNSKLHEDSSSL
HHHCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCCHHHH
RKQCFFPKNAQIINNPRGTAPGMIWEPIKGFTILTFPGVPSEMKTMWEETAYDFIQTKFS
HHHHCCCCCCEEECCCCCCCCCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
DTYSFFSNTLKFAGIGESSVAEKINDLLNLKNPTVAPYANLGEVKLRITARAKNEVEAKN
HHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
IIKPIKEKLKQEFSKFIFGEDNDTLPSILIKELTKRKQTIVFAESCTGGLLSASLTSISG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCC
SSQVFQGSIVSYSNELKHLLLDISEEKLAKYGAVSEEVCEAMAINVKKKLRADWAISISG
CCHHHHCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
IAGPNGGSQNKPVGLVYISISGPNNYITTIKKQFNSTRNRLEIQTLSVNVCLNSLRLILL
CCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCHHHEEEEEEEEHHHHHCCEEEEEE
SDSK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA