Click here to switch to the map view.

The map label for this gene is ureG

Identifier: 124265856

GI number: 124265856

Start: 699140

End: 699799

Strand: Reverse

Name: ureG

Synonym: Mpe_A0663

Alternate gene names: 124265856

Gene position: 699799-699140 (Counterclockwise)

Preceding gene: 124265857

Following gene: 124265855

Centisome position: 17.3

GC content: 67.27

Gene sequence:

>660_bases
ATGAGCGCATTGCATTCGATCCCCCACCGCAGCAAGAAGCTGCCCCCCCTGCGCGTGGGCGTCGGCGGCCCCGTCGGCTC
CGGCAAGACCACGCTGGTGGAGATGCTCTGCAAGAGCATGCGCGAGCGCTGGGACCTGGTGGTCGTGACCAACGACATCT
ACACCAAGGAAGACCAGCGCCTGCTCACGGTGTCGGGCGCGCTGGAGCCCGAACGCATCATGGGTGTGGAGACCGGCGGC
TGCCCGCACACGGCGATCCGCGAGGATGCGTCGATCAATCTCGAGGCGGTGGACCGCATGCTGGCGAAGTTCCCGAACGC
CGACATCGTGTTCATCGAGTCCGGCGGCGACAACCTCGCGGCCACCTTCAGCCCCGAGCTCAGCGACCTGACGATCTACG
TGATCGATGTCGCCGCCGGCGAGAAGATCCCGCGCAAGGGCGGCCCCGGCATCACCAAGAGCGACCTGTTCGTCATCAAC
AAGACCGATCTTGCGCCGCACGTCGGCGCCGACCTGGCCGTCATGGAGGCCGACACGCAGCGCATGCGGCCGGCCCATGC
GAGTTCGCGGCCCTACGTGATGACCAACCTGAAGACCCGCGCTGGCCTGGCCGAGGTGGTGAGCTTCATCGAGCGTCGCG
GACTGCTGCACGCGGCCTGA

Upstream 100 bases:

>100_bases
CTGTCGGCCCGCCACGAGACACAGTACTCGCGGCTGTTCCGCTCCTGAGCGAGCGGGGCCACGGCGTGGCCGGTGGCGCG
CTTCGTGCATCATCACCGCC

Downstream 100 bases:

>100_bases
GCCCCCTGCCCCGCGGGGGTAGGCGGTCTTTCATCGGCGCCGGGTCGCGGTGGGTTTAGAGTCGGCACTCCCCCTTCTCT
ATCCACCACGAAAGGACAAC

Product: urease accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSALHSIPHRSKKLPPLRVGVGGPVGSGKTTLVEMLCKSMRERWDLVVVTNDIYTKEDQRLLTVSGALEPERIMGVETGG
CPHTAIREDASINLEAVDRMLAKFPNADIVFIESGGDNLAATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLFVIN
KTDLAPHVGADLAVMEADTQRMRPAHASSRPYVMTNLKTRAGLAEVVSFIERRGLLHAA

Sequences:

>Translated_219_residues
MSALHSIPHRSKKLPPLRVGVGGPVGSGKTTLVEMLCKSMRERWDLVVVTNDIYTKEDQRLLTVSGALEPERIMGVETGG
CPHTAIREDASINLEAVDRMLAKFPNADIVFIESGGDNLAATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLFVIN
KTDLAPHVGADLAVMEADTQRMRPAHASSRPYVMTNLKTRAGLAEVVSFIERRGLLHAA
>Mature_218_residues
SALHSIPHRSKKLPPLRVGVGGPVGSGKTTLVEMLCKSMRERWDLVVVTNDIYTKEDQRLLTVSGALEPERIMGVETGGC
PHTAIREDASINLEAVDRMLAKFPNADIVFIESGGDNLAATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLFVINK
TDLAPHVGADLAVMEADTQRMRPAHASSRPYVMTNLKTRAGLAEVVSFIERRGLLHAA

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_METPP (A2SDI6)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019860.1
- ProteinModelPortal:   A2SDI6
- SMR:   A2SDI6
- STRING:   A2SDI6
- GeneID:   4784790
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0663
- NMPDR:   fig|279263.3.peg.3227
- eggNOG:   COG0378
- HOGENOM:   HBG364734
- OMA:   LCKAMRE
- ProtClustDB:   CLSK2321823
- BioCyc:   MPET420662:MPE_A0663-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 23654; Mature: 23522

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALHSIPHRSKKLPPLRVGVGGPVGSGKTTLVEMLCKSMRERWDLVVVTNDIYTKEDQR
CCCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEECCCCCE
LLTVSGALEPERIMGVETGGCPHTAIREDASINLEAVDRMLAKFPNADIVFIESGGDNLA
EEEEECCCCHHHEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEE
ATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLFVINKTDLAPHVGADLAVMEADTQ
EEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCHH
RMRPAHASSRPYVMTNLKTRAGLAEVVSFIERRGLLHAA
HCCCCCCCCCCEEEECCCHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SALHSIPHRSKKLPPLRVGVGGPVGSGKTTLVEMLCKSMRERWDLVVVTNDIYTKEDQR
CCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEECCCCCE
LLTVSGALEPERIMGVETGGCPHTAIREDASINLEAVDRMLAKFPNADIVFIESGGDNLA
EEEEECCCCHHHEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCEE
ATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLFVINKTDLAPHVGADLAVMEADTQ
EEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCHH
RMRPAHASSRPYVMTNLKTRAGLAEVVSFIERRGLLHAA
HCCCCCCCCCCEEEECCCHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA