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The map label for this gene is ureF

Identifier: 124265857

GI number: 124265857

Start: 699852

End: 700565

Strand: Reverse

Name: ureF

Synonym: Mpe_A0664

Alternate gene names: 124265857

Gene position: 700565-699852 (Counterclockwise)

Preceding gene: 124265858

Following gene: 124265856

Centisome position: 17.32

GC content: 74.65

Gene sequence:

>714_bases
ATGCCGCGCGTGCGCCGTCCGGCCGCGCCGACCGGCGCCGCCACACTGTTGGCCCTGATGTGGCTGGCTTCGCCGGCCCT
GCCGGTGGGCGGCTTCAGCTATTCCGAGGGCCTGGAGCCGGCGGTCGAGGCCGGCCTGGTGAGCGACGAGGCCACGGCAC
AGGCCTGGCTGCTCGATCAGCTGCTGCTGGGCCTCGGGCGTGGCGAGCTGGCGGTGGTGGCCCAGGCCGTGGCGGCCTGG
CGGCGCGGCGACGCGACGCGGGTGCGGGAACTCAACGACTGGCTGTTGTCCACCCGCGAGAGCGCCGAGCTGCGGCTGCA
GACCGAGCAGATGGGCCGCTCGCTCGGTGCCTGGCTGCAGCAGCGGCCCGGCACCGACGCTGCAGCCCTGGCGCGCCTGC
TCGCGCTGCCGCCCGCGCCCAGCTATCCGGTGGCGTTCGCGCTGGCCGCGGCCGGCACGCCCGCGAGCCTGCGCGAGGTG
GCGCTGGCCTACGCCTTCGGTTGGGCCGAGAACATGGTGCAGGCGGCGATCAAGGCGGTGCCATTGGGCCAGAGCGCCGG
CCAGCGCATGCTCGGTGCGCTGGTCGAGGCCATCCCCGCGACCGTGGACGCGGCGCTCGTGCTGCGTGACGGCGAACGCA
TGGCCTTCACGCCAATGCTCGCGGTGCTGTCGGCCCGCCACGAGACACAGTACTCGCGGCTGTTCCGCTCCTGA

Upstream 100 bases:

>100_bases
GGTCGGCGTGGCCATCAAGGCCGCCGCACCGGCACCACACGTGCACGGCCCCGGCTGCGGGCACGACCACGATCACGGCT
CCGGCCATCACCACTGAGCG

Downstream 100 bases:

>100_bases
GCGAGCGGGGCCACGGCGTGGCCGGTGGCGCGCTTCGTGCATCATCACCGCCATGAGCGCATTGCATTCGATCCCCCACC
GCAGCAAGAAGCTGCCCCCC

Product: urease accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MPRVRRPAAPTGAATLLALMWLASPALPVGGFSYSEGLEPAVEAGLVSDEATAQAWLLDQLLLGLGRGELAVVAQAVAAW
RRGDATRVRELNDWLLSTRESAELRLQTEQMGRSLGAWLQQRPGTDAAALARLLALPPAPSYPVAFALAAAGTPASLREV
ALAYAFGWAENMVQAAIKAVPLGQSAGQRMLGALVEAIPATVDAALVLRDGERMAFTPMLAVLSARHETQYSRLFRS

Sequences:

>Translated_237_residues
MPRVRRPAAPTGAATLLALMWLASPALPVGGFSYSEGLEPAVEAGLVSDEATAQAWLLDQLLLGLGRGELAVVAQAVAAW
RRGDATRVRELNDWLLSTRESAELRLQTEQMGRSLGAWLQQRPGTDAAALARLLALPPAPSYPVAFALAAAGTPASLREV
ALAYAFGWAENMVQAAIKAVPLGQSAGQRMLGALVEAIPATVDAALVLRDGERMAFTPMLAVLSARHETQYSRLFRS
>Mature_236_residues
PRVRRPAAPTGAATLLALMWLASPALPVGGFSYSEGLEPAVEAGLVSDEATAQAWLLDQLLLGLGRGELAVVAQAVAAWR
RGDATRVRELNDWLLSTRESAELRLQTEQMGRSLGAWLQQRPGTDAAALARLLALPPAPSYPVAFALAAAGTPASLREVA
LAYAFGWAENMVQAAIKAVPLGQSAGQRMLGALVEAIPATVDAALVLRDGERMAFTPMLAVLSARHETQYSRLFRS

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0830

COG function: function code O; Urease accessory protein UreF

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREF_METPP (A2SDI7)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019861.1
- STRING:   A2SDI7
- GeneID:   4784791
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0664
- NMPDR:   fig|279263.3.peg.3228
- eggNOG:   COG0830
- HOGENOM:   HBG709295
- OMA:   SPQLPIG
- ProtClustDB:   CLSK722448
- BioCyc:   MPET420662:MPE_A0664-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01385
- InterPro:   IPR002639
- PIRSF:   PIRSF009467

Pfam domain/function: PF01730 UreF

EC number: NA

Molecular weight: Translated: 25108; Mature: 24977

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVRRPAAPTGAATLLALMWLASPALPVGGFSYSEGLEPAVEAGLVSDEATAQAWLLDQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHCCCCCHHHHHHHHHHH
LLLGLGRGELAVVAQAVAAWRRGDATRVRELNDWLLSTRESAELRLQTEQMGRSLGAWLQ
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHH
QRPGTDAAALARLLALPPAPSYPVAFALAAAGTPASLREVALAYAFGWAENMVQAAIKAV
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGQSAGQRMLGALVEAIPATVDAALVLRDGERMAFTPMLAVLSARHETQYSRLFRS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRVRRPAAPTGAATLLALMWLASPALPVGGFSYSEGLEPAVEAGLVSDEATAQAWLLDQ
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHCCCCCHHHHHHHHHHH
LLLGLGRGELAVVAQAVAAWRRGDATRVRELNDWLLSTRESAELRLQTEQMGRSLGAWLQ
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHH
QRPGTDAAALARLLALPPAPSYPVAFALAAAGTPASLREVALAYAFGWAENMVQAAIKAV
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGQSAGQRMLGALVEAIPATVDAALVLRDGERMAFTPMLAVLSARHETQYSRLFRS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA