| Definition | Prochlorococcus marinus str. MIT 9515, complete genome. |
|---|---|
| Accession | NC_008817 |
| Length | 1,704,176 |
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The map label for this gene is lysA [H]
Identifier: 123966414
GI number: 123966414
Start: 1037731
End: 1039104
Strand: Direct
Name: lysA [H]
Synonym: P9515_11811
Alternate gene names: 123966414
Gene position: 1037731-1039104 (Clockwise)
Preceding gene: 123966408
Following gene: 123966415
Centisome position: 60.89
GC content: 32.1
Gene sequence:
>1374_bases ATGAATGAAAAAATTTCTTTTTTAAAAAATAAAATAAATTTAAGTAGTCCTAACAAAAATATTGTACCTATAACTACCAA TATTGACATTACCGAAAAGTTAAATATTGGTGGTTGTTCTATTGAAGATTTGGTAAAAAAATACGAATCGCCTTTATATA TATTGGATGAAATCACTTTAAGAAATTCCTGTAGAGCTTACAAAAAAGCATTAGAAAAATATTATCGAGGAGTGTCCCTA CCAATATATGCCTCTAAAGCAAATAGTTCATTATTTATGAGTAATCTGGTAGCTTCAGAGGGATTTGGTCTTGATGCAGT TTCAGAAGGTGAATTACTGACTGCTTTAAAAGGGGGAGTGCCAAATGAAAAAATTGTTTTTCATGGAAATAATAAATCTG ATAAGGAAATTGCATTTGCCATAAAAAATAAAATCAAAGTAATTGTAGATAATGAACATGACCTTAAAAGACTAGAAGAA ATATCTAATTCATTAAATTTTGATCTAGAAATAATGATTAGATTTACCCCGGGAATAGAATGCCATACCCATGAATACAT AAGAACCGGTTCTTTTGATAGCAAGTTTGGCTTTGGAATTGAGTCTCTAACTAAGTTATTCGGAGTGATAATCAAAACCA AGCACCTAAAATTAATTGGATTACATGCTCATATAGGTTCTCAGATCTTTGAACTTGAACCACATAAAGATCTCGGAGAG ATAATGGTAAATGTTATGCTCCAAGCTAAAAAGTTTGGCCACAACATAAAAGAACTAAATGTCGGAGGTGGATTAGGAAT TAAATATACCCAGGAAGATGATCCTCCTTCCATTGATGAGTGGATCAAAACAGTTTCTTCATCCATTGAACAAGCTTGTA AAAAAAATAAATTAGATTTACCTTTACTTATGTGTGAGCCTGGGAGATCAATAGTTTCTACCGCTGGGGTAACAATATAC AAAATTGGCTCATTTAAAGAAATTCCTGGGATAAGGACATACCTATCAGTTGATGGTGGCATGAGTGATAATCCCAGGCC AATCACATATCAATCTAATTATTCTGCTTGTTTAGTAAATGACCCTTTAAATATTAATTCCAAAAATAAATATACTGTTG CGGGTAAGCATTGTGAGTCTGGAGACGTTTTATTTAAGGAAATTGAACTAGGTAAATGTAAAACAGGTGATTTGATTTGT GTTTTTGGTACTGGCGCATACAATAATTCAATGAGTTCTAATTACAACAGAATTCCTAAACCTGCTGCTGTTTTAGTTTG TAATGGGGAAGCAGAAATAATTCAAAAAAGAGAAAGTCCACATGATCTTCTTAAAAACGATGTCTTACCCGATCGCTTTA TCAATCAAAGTTAG
Upstream 100 bases:
>100_bases AATCATTAAATTAATTATTGTCTCTTATAGTAATTTTAAAATTAAATTAATAATAGAAGTTCTGAAAGTTGTAGAATGAT TTTATGTGAAAAGAGAACCT
Downstream 100 bases:
>100_bases GTACATTTAAATAAATTAAATTTTAATGTGAATTTTTGGGGGTTTATAAACTTAAAGTTTTTATTAGATGTATTATTTGC AGCTGGATTTGGACTTTTAT
Product: diaminopimelate decarboxylase
Products: NA
Alternate protein names: DAP decarboxylase [H]
Number of amino acids: Translated: 457; Mature: 457
Protein sequence:
>457_residues MNEKISFLKNKINLSSPNKNIVPITTNIDITEKLNIGGCSIEDLVKKYESPLYILDEITLRNSCRAYKKALEKYYRGVSL PIYASKANSSLFMSNLVASEGFGLDAVSEGELLTALKGGVPNEKIVFHGNNKSDKEIAFAIKNKIKVIVDNEHDLKRLEE ISNSLNFDLEIMIRFTPGIECHTHEYIRTGSFDSKFGFGIESLTKLFGVIIKTKHLKLIGLHAHIGSQIFELEPHKDLGE IMVNVMLQAKKFGHNIKELNVGGGLGIKYTQEDDPPSIDEWIKTVSSSIEQACKKNKLDLPLLMCEPGRSIVSTAGVTIY KIGSFKEIPGIRTYLSVDGGMSDNPRPITYQSNYSACLVNDPLNINSKNKYTVAGKHCESGDVLFKEIELGKCKTGDLIC VFGTGAYNNSMSSNYNRIPKPAAVLVCNGEAEIIQKRESPHDLLKNDVLPDRFINQS
Sequences:
>Translated_457_residues MNEKISFLKNKINLSSPNKNIVPITTNIDITEKLNIGGCSIEDLVKKYESPLYILDEITLRNSCRAYKKALEKYYRGVSL PIYASKANSSLFMSNLVASEGFGLDAVSEGELLTALKGGVPNEKIVFHGNNKSDKEIAFAIKNKIKVIVDNEHDLKRLEE ISNSLNFDLEIMIRFTPGIECHTHEYIRTGSFDSKFGFGIESLTKLFGVIIKTKHLKLIGLHAHIGSQIFELEPHKDLGE IMVNVMLQAKKFGHNIKELNVGGGLGIKYTQEDDPPSIDEWIKTVSSSIEQACKKNKLDLPLLMCEPGRSIVSTAGVTIY KIGSFKEIPGIRTYLSVDGGMSDNPRPITYQSNYSACLVNDPLNINSKNKYTVAGKHCESGDVLFKEIELGKCKTGDLIC VFGTGAYNNSMSSNYNRIPKPAAVLVCNGEAEIIQKRESPHDLLKNDVLPDRFINQS >Mature_457_residues MNEKISFLKNKINLSSPNKNIVPITTNIDITEKLNIGGCSIEDLVKKYESPLYILDEITLRNSCRAYKKALEKYYRGVSL PIYASKANSSLFMSNLVASEGFGLDAVSEGELLTALKGGVPNEKIVFHGNNKSDKEIAFAIKNKIKVIVDNEHDLKRLEE ISNSLNFDLEIMIRFTPGIECHTHEYIRTGSFDSKFGFGIESLTKLFGVIIKTKHLKLIGLHAHIGSQIFELEPHKDLGE IMVNVMLQAKKFGHNIKELNVGGGLGIKYTQEDDPPSIDEWIKTVSSSIEQACKKNKLDLPLLMCEPGRSIVSTAGVTIY KIGSFKEIPGIRTYLSVDGGMSDNPRPITYQSNYSACLVNDPLNINSKNKYTVAGKHCESGDVLFKEIELGKCKTGDLIC VFGTGAYNNSMSSNYNRIPKPAAVLVCNGEAEIIQKRESPHDLLKNDVLPDRFINQS
Specific function: Lysine biosynthesis; last step. [C]
COG id: COG0019
COG function: function code E; Diaminopimelate decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]
Homologues:
Organism=Escherichia coli, GI1789203, Length=431, Percent_Identity=28.3062645011601, Blast_Score=147, Evalue=1e-36, Organism=Escherichia coli, GI1789307, Length=280, Percent_Identity=25.3571428571429, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI24586474, Length=398, Percent_Identity=23.8693467336683, Blast_Score=75, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR002986 - InterPro: IPR022643 - InterPro: IPR022644 - InterPro: IPR022653 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: =4.1.1.20 [H]
Molecular weight: Translated: 50700; Mature: 50700
Theoretical pI: Translated: 7.72; Mature: 7.72
Prosite motif: PS00879 ODR_DC_2_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNEKISFLKNKINLSSPNKNIVPITTNIDITEKLNIGGCSIEDLVKKYESPLYILDEITL CCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEEHHH RNSCRAYKKALEKYYRGVSLPIYASKANSSLFMSNLVASEGFGLDAVSEGELLTALKGGV HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCC PNEKIVFHGNNKSDKEIAFAIKNKIKVIVDNEHDLKRLEEISNSLNFDLEIMIRFTPGIE CCCEEEEECCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCE CHTHEYIRTGSFDSKFGFGIESLTKLFGVIIKTKHLKLIGLHAHIGSQIFELEPHKDLGE ECCCHHEECCCCCCCCCCCHHHHHHHHHHHHEECCEEEEEEEHHHCCEEEEECCCCCHHH IMVNVMLQAKKFGHNIKELNVGGGLGIKYTQEDDPPSIDEWIKTVSSSIEQACKKNKLDL HHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC PLLMCEPGRSIVSTAGVTIYKIGSFKEIPGIRTYLSVDGGMSDNPRPITYQSNYSACLVN EEEEECCCCHHHHHCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEE DPLNINSKNKYTVAGKHCESGDVLFKEIELGKCKTGDLICVFGTGAYNNSMSSNYNRIPK CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC PAAVLVCNGEAEIIQKRESPHDLLKNDVLPDRFINQS CEEEEEECCCHHHHHCCCCHHHHHHHCCCCCHHCCCC >Mature Secondary Structure MNEKISFLKNKINLSSPNKNIVPITTNIDITEKLNIGGCSIEDLVKKYESPLYILDEITL CCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEEHHH RNSCRAYKKALEKYYRGVSLPIYASKANSSLFMSNLVASEGFGLDAVSEGELLTALKGGV HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCC PNEKIVFHGNNKSDKEIAFAIKNKIKVIVDNEHDLKRLEEISNSLNFDLEIMIRFTPGIE CCCEEEEECCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCE CHTHEYIRTGSFDSKFGFGIESLTKLFGVIIKTKHLKLIGLHAHIGSQIFELEPHKDLGE ECCCHHEECCCCCCCCCCCHHHHHHHHHHHHEECCEEEEEEEHHHCCEEEEECCCCCHHH IMVNVMLQAKKFGHNIKELNVGGGLGIKYTQEDDPPSIDEWIKTVSSSIEQACKKNKLDL HHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC PLLMCEPGRSIVSTAGVTIYKIGSFKEIPGIRTYLSVDGGMSDNPRPITYQSNYSACLVN EEEEECCCCHHHHHCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEE DPLNINSKNKYTVAGKHCESGDVLFKEIELGKCKTGDLICVFGTGAYNNSMSSNYNRIPK CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC PAAVLVCNGEAEIIQKRESPHDLLKNDVLPDRFINQS CEEEEEECCCHHHHHCCCCHHHHHHHCCCCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8590279; 8905231 [H]