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The map label for this gene is glsA [H]

Identifier: 120598137

GI number: 120598137

Start: 1496466

End: 1497380

Strand: Direct

Name: glsA [H]

Synonym: Sputw3181_1314

Alternate gene names: 120598137

Gene position: 1496466-1497380 (Clockwise)

Preceding gene: 120598136

Following gene: 120598138

Centisome position: 31.78

GC content: 46.34

Gene sequence:

>915_bases
ATGCCCGAGTTGGCATTACTTGAGGAAGTGGTCGAGAAAGTTCGACCCTTGCTCGGCCAAGGAAAAGTTGCAAATTATAT
CCCCGCACTGGCTAGCGTTGATGCTGGCAAATTAGGCATTGCCGTCACGACTGTTGATGGTGAAACTTTAGGTGCGGGCG
ATTACCTTGAGCCGTTTTCGATTCAAAGTATCTCTAAAGTTTTCAGCTTAACCTTAGCGTTAACTTTATATGAAGAAGCC
GAAATCTGGAGCCGTGTTGGCAAAGAACCTTCGGGCCATTCCTTCAATTCTCTTGTTCAAGTCGAGTTAGAACGTGGCAA
GCCGCGCAATCCCTTTATCAATGCTGGCGCGTTAGTGATTGCTGACTTATTGCAGAGCCGTTTAGGTGCGCCTAAACACA
GAATGCTTGAGTTAGTTAGGCAACTCAGCCAAAACGATAAAGTGTGTTTTGATAAACAAGTGGCAGATTCAGAATATCAG
CATAGTGCGCGCAATGCGGCTATCGCTTATTTGATGAAGTCGTTTGGTAATTTTCAAGGCGATGTTGATACTGTGCTGCG
CACTTATTTTCATTACTGCGCCCTAAAAATGAATTGTGCTGATTTATCTAGGGCCATGTTGTATTTGGCGAATCGCGGCA
AAACTGTGGATGGCACTGAGCTGATTTCTCAAGTTCAAACTCGGCAACTTAACGCTCTGTTGGCCACCTCGGGCTTATAT
GATGGCGCGGGTGAATTTGCTTATCGTGTTGGTATGCCTGGTAAAAGTGGCGTCGGTGGCGGTATTATTGCGGTTATCCC
TGGCGAGTTATCGATTTGTGTTTGGTCACCAGAGCTTGATGAGAATGGCAACTCACTTGCGGGTACTGCTATGCTTGAGC
ATCTAAGTCAGCGTCTTGGGCGCTCTATTTTCTAG

Upstream 100 bases:

>100_bases
AATGTACCGAAGAAGATATTGCTGCAGTTAAGGCATTCTGGGCGACTCAAAAAGTGTCCCAGGTTGAAGTTAGCGAACTG
TACGATATTTGGTGGGGTTA

Downstream 100 bases:

>100_bases
CTTCCCTCGTTTTTATTAGCGCTATTAAGCTAAAACTAGCGAATTTCGCCATGTTAGCATTAGCGCTAACTTTTCTATAT
TCATCATAATCAATACGTTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFSIQSISKVFSLTLALTLYEEA
EIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQ
HSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLGRSIF

Sequences:

>Translated_304_residues
MPELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFSIQSISKVFSLTLALTLYEEA
EIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQ
HSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLGRSIF
>Mature_303_residues
PELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFSIQSISKVFSLTLALTLYEEAE
IWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQH
SARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLYD
GAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=294, Percent_Identity=35.0340136054422, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=4e-39,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=63.4551495016611, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=35.9861591695502, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=296, Percent_Identity=36.1486486486487, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17532727, Length=297, Percent_Identity=32.6599326599327, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193204073, Length=310, Percent_Identity=33.2258064516129, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=312, Percent_Identity=33.0128205128205, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32911; Mature: 32780

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCH
IQSISKVFSLTLALTLYEEAEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQG
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC
>Mature Secondary Structure 
PELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCH
IQSISKVFSLTLALTLYEEAEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQG
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA