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The map label for this gene is thiL [H]

Identifier: 119945901

GI number: 119945901

Start: 2724929

End: 2725936

Strand: Reverse

Name: thiL [H]

Synonym: Ping_2241

Alternate gene names: 119945901

Gene position: 2725936-2724929 (Counterclockwise)

Preceding gene: 119945902

Following gene: 119945897

Centisome position: 59.78

GC content: 41.17

Gene sequence:

>1008_bases
ATGAATCTCAGTGAATTTGATTTGATAGACAGCTATTTTAAACGCAGCACAACAGTTCAAAATAGTGGTGTGGCGTTAGG
GATCGGTGATGATTGTGCTCTTTTGGATATTCCAGAGGGTTACCAATTGGCCGTTAGCACTGACAGTTTAGTGTGTGGCG
TCCATTTCTTTGAGGATGTTGACCCATATCGGTTAGGTTATAAGGCGCTTGCCGTGAACCTTAGCGACTTAGCTGCGATG
GGCGCATTACCTAAATGGGTTTCCCTTGCTATTACGTTACCCAATGGTGCTATGGTGAATAATAATCCCAATTGGTTATC
TGAATTTACACGCGGCTTTTTTGCATTAGCAGACAAATTCGATGTGGTGTTGGTGGGGGGTGATACAACAAAAGGTCCTT
TATCGATCACTGTTTCTGTGAAAGGTATTGTTCCTCGAGGGTTAGCGCTGCAACGTAATAAAGCTAACTTGGGCGATCTG
ATTTGTGTTTCAAATTTTATTGGAGATGGCGCTTTAGGCTTGTCTATAAAATTAAATGAGTTAGCGGTCACAAATCCTCA
GTACTTTGTGGATGCGTTAGAGCTGACTGAGCCGCGTGTTGATCTCGGTATTTTATTACGCGGTTTAGCATCAAGCTGTA
TAGATATCTCCGATGGTTTAACCCAGGATCTTATCCATATTTTGAAAGCGTCTCATTGCGCTGCAAACATTGCGATAGAA
TCTTTACCCTTGTCAAAAACGATGCGGAAAGAAGTTAATTTAGGAAAGCTTAACAATGATGAGGCAGTACAATACGCATT
AACCGGTGGGGATGATTATGAATTATTATTTACAATCAGTGAAAATAATTTAAGGCTATTAGAGCAGAGAATAGCTCAAC
AAACACAGCCTATACCAAGCCTTTCCGTGATCGGCCGTACGACTTTACAACAATCTGAATTAATCGCGTTTTTTAAAGAA
AAGCAAGCGGTTACTTATTCGACGGGCGGATGGGATCATTTTAAGTAG

Upstream 100 bases:

>100_bases
ATAGTCATCAGCCGGCAAAAAAAATATTTATCAATAAAAACAGCAAAAACACAACAACACCAACTGCCAATGTAAAAGCA
ACCTTGAAGTTAAAACGTAA

Downstream 100 bases:

>100_bases
ATTTAAAATTAGAATGATCAATAGCTAAGAAGATTAAAATTAAGTGATCCAGTGTATTCAGTGGTTTAGCAAATGAATAT
CAGTAGGCTATCTGCTGCAG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNLSEFDLIDSYFKRSTTVQNSGVALGIGDDCALLDIPEGYQLAVSTDSLVCGVHFFEDVDPYRLGYKALAVNLSDLAAM
GALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKFDVVLVGGDTTKGPLSITVSVKGIVPRGLALQRNKANLGDL
ICVSNFIGDGALGLSIKLNELAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAANIAIE
SLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQPIPSLSVIGRTTLQQSELIAFFKE
KQAVTYSTGGWDHFK

Sequences:

>Translated_335_residues
MNLSEFDLIDSYFKRSTTVQNSGVALGIGDDCALLDIPEGYQLAVSTDSLVCGVHFFEDVDPYRLGYKALAVNLSDLAAM
GALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKFDVVLVGGDTTKGPLSITVSVKGIVPRGLALQRNKANLGDL
ICVSNFIGDGALGLSIKLNELAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAANIAIE
SLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQPIPSLSVIGRTTLQQSELIAFFKE
KQAVTYSTGGWDHFK
>Mature_335_residues
MNLSEFDLIDSYFKRSTTVQNSGVALGIGDDCALLDIPEGYQLAVSTDSLVCGVHFFEDVDPYRLGYKALAVNLSDLAAM
GALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKFDVVLVGGDTTKGPLSITVSVKGIVPRGLALQRNKANLGDL
ICVSNFIGDGALGLSIKLNELAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAANIAIE
SLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQPIPSLSVIGRTTLQQSELIAFFKE
KQAVTYSTGGWDHFK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=337, Percent_Identity=45.1038575667656, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36314; Mature: 36314

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSEFDLIDSYFKRSTTVQNSGVALGIGDDCALLDIPEGYQLAVSTDSLVCGVHFFEDV
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECCCEEEEEHHHCCC
DPYRLGYKALAVNLSDLAAMGALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKF
CCHHHCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHCCCCC
DVVLVGGDTTKGPLSITVSVKGIVPRGLALQRNKANLGDLICVSNFIGDGALGLSIKLNE
EEEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEHHHCCCCEEEEEEEEEE
LAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAANIAIE
EEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHEEEEE
SLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQPIPS
CCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
LSVIGRTTLQQSELIAFFKEKQAVTYSTGGWDHFK
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
>Mature Secondary Structure
MNLSEFDLIDSYFKRSTTVQNSGVALGIGDDCALLDIPEGYQLAVSTDSLVCGVHFFEDV
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECCCEEEEEHHHCCC
DPYRLGYKALAVNLSDLAAMGALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKF
CCHHHCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHCCCCC
DVVLVGGDTTKGPLSITVSVKGIVPRGLALQRNKANLGDLICVSNFIGDGALGLSIKLNE
EEEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEHHHCCCCEEEEEEEEEE
LAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAANIAIE
EEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHEEEEE
SLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQPIPS
CCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCC
LSVIGRTTLQQSELIAFFKEKQAVTYSTGGWDHFK
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]