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The map label for this gene is hsaD [H]

Identifier: 119716999

GI number: 119716999

Start: 2945909

End: 2946817

Strand: Reverse

Name: hsaD [H]

Synonym: Noca_2775

Alternate gene names: 119716999

Gene position: 2946817-2945909 (Counterclockwise)

Preceding gene: 119717000

Following gene: 119716998

Centisome position: 59.1

GC content: 72.28

Gene sequence:

>909_bases
TTGGCTCTCACGAAGGAGAGCGCGCAGCGCTCCGCCAAGGCGAAGGACATCACGCTCAGCTACTACGAGGCCGGGACCGC
GGCGACCTCCGCGACCGGGGCGCCGGTCGGCGGCGGGCTGCCGCTCGTGATGCTGCACGGCGGTGGGCCGGGAGCATCGG
CGTGGTCGAACTTCGGCAGCGCGCTGCCGAGGTTCGCCGCGTCGTTCCGCACCCTGCTCGTCGACCAGCCCGGCTTCGGC
GCCTCCGACAAGCCACCGGTCGTCGGCAACTACTACCGCCACTCCGCCGACCACGTGGTCGCGCTGCTCGACGAGCTCGG
CATCGACCGGGTGCACCTGCTCGGCAACAGCCTCGGCGGCGGTACGGCGATGCGGCTCGCGCTCGACCACCCCGACCGCG
TCGGGCGGCTGGTCCTGATGGGTCCCGGCGGGCTCTCGCTCAACCTGTTCCACGCCGACCCGACCGAGGGCGTGCAGCGG
CTGATGGACTTCGGGGCCGAGCCGACGCGGGAGAACCTGCGGGCGTTCATCTCGACGATGGTGGTCGACCAGCGGCTGGT
CACCGACGAGCTGGTCGAGGAGCGGTTCGCCGACGCGACCGCCCCCGGCGCCCAGGACGCGATGCGCTCGATGGGGATGT
CCTTCTGGAACCCCGAGACGGCCGAGGACGGCATGCTCTGGCGCGAGGCGCACCGGCTGCGCAAGCACACCCTGCTGACC
TGGGGCCGCGAGGACCGGGTCAACCCGCTCGACGGCGCGTTCGCCGCCCTCAAGCTGATCCCGAAGGCCCAGCTGCATGT
CTTCGCGAACTGCGGGCACTGGGCGCAGGTCGAGGCCGCCGACGAGTTCGCCGAGGTCTCCATCGCGTTCCTGGCCCGGC
ACGTCGAGCGCCCCGAGGGGGAGTCGTGA

Upstream 100 bases:

>100_bases
CACGCCGGCCGGGTGCACGCCGCCAACGACCCCGAGCGGGCGCTGCAGATGTACGGCGCGCACGAGTTCGGGCACAAGAT
CGACCCGGGGATGTACTGAG

Downstream 100 bases:

>100_bases
CCATCGACATCAAGTCCATGGGCTACGTCCGCGTGGCCAGCACCGACCTGTCCCGGTGGGAGACCTTCGCGGGCAAGGTC
CTCGGGCTCGCCGCCGGCCG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MALTKESAQRSAKAKDITLSYYEAGTAATSATGAPVGGGLPLVMLHGGGPGASAWSNFGSALPRFAASFRTLLVDQPGFG
ASDKPPVVGNYYRHSADHVVALLDELGIDRVHLLGNSLGGGTAMRLALDHPDRVGRLVLMGPGGLSLNLFHADPTEGVQR
LMDFGAEPTRENLRAFISTMVVDQRLVTDELVEERFADATAPGAQDAMRSMGMSFWNPETAEDGMLWREAHRLRKHTLLT
WGREDRVNPLDGAFAALKLIPKAQLHVFANCGHWAQVEAADEFAEVSIAFLARHVERPEGES

Sequences:

>Translated_302_residues
MALTKESAQRSAKAKDITLSYYEAGTAATSATGAPVGGGLPLVMLHGGGPGASAWSNFGSALPRFAASFRTLLVDQPGFG
ASDKPPVVGNYYRHSADHVVALLDELGIDRVHLLGNSLGGGTAMRLALDHPDRVGRLVLMGPGGLSLNLFHADPTEGVQR
LMDFGAEPTRENLRAFISTMVVDQRLVTDELVEERFADATAPGAQDAMRSMGMSFWNPETAEDGMLWREAHRLRKHTLLT
WGREDRVNPLDGAFAALKLIPKAQLHVFANCGHWAQVEAADEFAEVSIAFLARHVERPEGES
>Mature_301_residues
ALTKESAQRSAKAKDITLSYYEAGTAATSATGAPVGGGLPLVMLHGGGPGASAWSNFGSALPRFAASFRTLLVDQPGFGA
SDKPPVVGNYYRHSADHVVALLDELGIDRVHLLGNSLGGGTAMRLALDHPDRVGRLVLMGPGGLSLNLFHADPTEGVQRL
MDFGAEPTRENLRAFISTMVVDQRLVTDELVEERFADATAPGAQDAMRSMGMSFWNPETAEDGMLWREAHRLRKHTLLTW
GREDRVNPLDGAFAALKLIPKAQLHVFANCGHWAQVEAADEFAEVSIAFLARHVERPEGES

Specific function: Catalyzes the hydrolysis of a carbon-carbon bond in 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA) to yield 9,17-dioxo-1,2,3,4,10,19- hexanorandrostan-5-oic acid (DOHNAA) and 2-hydroxy-hexa-2,4- dienoic acid (HHD). Al

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HsaD family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=277, Percent_Identity=37.1841155234657, Blast_Score=177, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 32509; Mature: 32378

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKESAQRSAKAKDITLSYYEAGTAATSATGAPVGGGLPLVMLHGGGPGASAWSNFGS
CCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
ALPRFAASFRTLLVDQPGFGASDKPPVVGNYYRHSADHVVALLDELGIDRVHLLGNSLGG
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTAMRLALDHPDRVGRLVLMGPGGLSLNLFHADPTEGVQRLMDFGAEPTRENLRAFISTM
CEEEEEEECCCHHHCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VVDQRLVTDELVEERFADATAPGAQDAMRSMGMSFWNPETAEDGMLWREAHRLRKHTLLT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEE
WGREDRVNPLDGAFAALKLIPKAQLHVFANCGHWAQVEAADEFAEVSIAFLARHVERPEG
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
ES
CC
>Mature Secondary Structure 
ALTKESAQRSAKAKDITLSYYEAGTAATSATGAPVGGGLPLVMLHGGGPGASAWSNFGS
CCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
ALPRFAASFRTLLVDQPGFGASDKPPVVGNYYRHSADHVVALLDELGIDRVHLLGNSLGG
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTAMRLALDHPDRVGRLVLMGPGGLSLNLFHADPTEGVQRLMDFGAEPTRENLRAFISTM
CEEEEEEECCCHHHCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VVDQRLVTDELVEERFADATAPGAQDAMRSMGMSFWNPETAEDGMLWREAHRLRKHTLLT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEE
WGREDRVNPLDGAFAALKLIPKAQLHVFANCGHWAQVEAADEFAEVSIAFLARHVERPEG
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
ES
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA