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The map label for this gene is cutL [H]

Identifier: 119714491

GI number: 119714491

Start: 240198

End: 242573

Strand: Direct

Name: cutL [H]

Synonym: Noca_0224

Alternate gene names: 119714491

Gene position: 240198-242573 (Clockwise)

Preceding gene: 119714490

Following gene: 119714492

Centisome position: 4.82

GC content: 71.76

Gene sequence:

>2376_bases
ATGACCGCGACCGTCCCGATCGGGCACGGCCGGATGCTCCGCAAGGAGGACCGGCGGTTCGTGCGCGGCCGCGGGAAGTA
CCTCGACGACATCGCGCTGCCGGGAATGCTGCACCTCGCCGTGCTGCGGTCGCCGGTCGCGCACGCGCGGATCCTCTCCA
TCGACACGCTCGCGGCCGAGGCGCACCCGAAGGTGAAGGCGGTCGTCACCGGCGCGCTGCTCGCCGAGCGCGGCCTCGCC
TGGATGCCCACCCTCTCCGGCGACGTGCAGGCCGTGCTGGCCACCGACAAGGTCCGCTTCCAGGGCCAGGAGGTCGCGTT
CGTCGTCGCCGAGGACCGCTACTCCGCGCGCGACGCCCTCGAGCTGATCGACGTCGAGTACGACGTGCTCCCGCCGGTCG
TCGACGTGCGCCGCGCCCTCGACGCGGACGCCCCGCTCATCCGCGACGACGTGGCCGGCAAGACCGACAACCACTGCTTC
GACTGGGAGACCGGTGACGCGGCGGCGACCGACGCGGTGTTCGACCGGGCCGAGGTCGTCGTCCGACAGGAGATCGTGTT
CCCGCGGGTGCACCCGGCACCGCTGGAGACTTGCGGCGCGGTCGCCGACTACGACCGGGTCGAGCAGAAGCTCACCCTCT
GGGCGACCACCCAGGCGCCGCACGCCCACCGGACGCTGTACTCCATGTTCGCGGGCCTCCCCGAGCACAAGATCCGGGTG
ATCTCGCCGGACATCGGCGGCGGCTTCGGCAACAAGGTGCCGATCTACCCCGGCTACGTCTGCGCGATCGTGGGCTCGAT
GGTCACCGGCCGGCCGGTGAAGTGGACCGAGGACCGCACCGAGAACCTCGTGGCGTCCGGGTTCGCCCGCGACTACGTGA
TGCAGGGCGAGATCGCCGCGACCCGCGACGGGCGGATCCTCGCGCTGCGCAGCCACGTGCTCGCCGACCACGGCGCCTTC
AACGGGACCGCGGCGCCGCGGAAGTTCCCGGGCGGCTTCTTCGGCGTCTTCACCGGCAGCTACGACATCGAGGCGGCGTA
CTGCTCGATGACCGCGGTGCACACCAACAAGGCGCCCGGCGGGGTCGCCTATGCGTGCTCGTTCCGGATCGCCGAGGCCG
TCTACCTGGTCGAGCGGATGGTCGACCTGCTCGCCGACGAGCTCGGCATCGACCCGGTCGAGCTGCGGCTGCGCAACTTC
ATCCGCAGCGACCAGTTCCCGTACACGTCGCGCACCGGCTGGGTCTACGACTCCGGCGACTACGCGACGACCATGCAGGA
GGCGCTGCGGATCGCGGGGTACGACGAGCTCCGGGCCGAGCAGGCCGCGCGCCGCGCCGCCGGGGACGGGCAGAGCCTGA
TGGGGATCGGCGTCTCGTTCTTCACCGAGGCCGTCGGGGCCGGTCCGCGCAAGGACATGGACATGCTCGGCCTCGGCATG
GCCGACGGGTGTGAGCTGCGGGTGCACCCGACCGGGTCGGCCGTGCTGCGGATCGCGGTGCAGACGCAGGGCCAGGGGCA
CGAGACGACCTTCGCCCAGCTGGTCGCCGAGGAGCTCGGCATCCACCCCGAGAACATCGACGTGGTGCACGGCGACACCG
ACAACACGCCTTACGGCCTGGGAACGTACGGGTCGCGGTCGACCCCGGTGTCCGGGGCGGCGGCGGTCATCGCGTCGCGG
CGGGTACGCGAGAAGGCGCGGCTGATCGCGGCCGGGATGCTCGAGGTGGCCCCGGACGACCTCGAGTGGACCAAGGACGC
GGCCGGGGGGCGGTTCGGCGTGCGGGGGGTCCCCGGCGCGAGCGTCACGATCGAGCAGGTCGCGATGCGCGCGCACGGCG
CCGACGAGCTCCCCGAGGGTGTGGAGGGCGGGCTGGACGCGCAGGTGTCCTACAACCCCGACAACCTCACCTATCCCTAC
GGCGCCTACATCTGCGTCGTCGACATCGACCCCGGCACCGCCGTGGTCAAGGTGCGGCGGTTCGTCGCCGTCGACGACTG
CGGGACCCGCATCAACGAGATGATCGTCGAGGGGCAGATCCACGGCGGTCTGACCGACGGGGTCGGCATGGCCCTGATGG
AGTACATCGGGTACGACGAGCACGGCAACTGCCTCGGCGGCTCGCTCATGGACTACCTGATCCCCACGGCCAAGGAGGTG
CCCGACTGGGAGACCGGCATGACCGTCACCCCCTCGCCGCACCACCCGATCGGCGCCAAGGGTGTCGGCGAGTCCGCCAC
CGTCGGCTCTCCGCCTGCGGTCGTCAACGCGGTGATCGACGCGCTCGCGCCGTACGGCGTGCGGCACGCCGACATGCCGC
TCACCCCGTCCCGGGTCTGGGAGGCGATGCACGGCCGTGCCACGCCTCCTCAGTGA

Upstream 100 bases:

>100_bases
GGGAGGCGATCTCGGGACAGATCTGCCGGTGCACCGGCTACGCCTCGATCGTCCGCTCCGTGCGCTGGGCCGCCGACCAC
CCCGAGGGGAGGATCGAGGC

Downstream 100 bases:

>100_bases
CGCCACCGCGCTGGTGCTGGCGGCCGGCGGCTCGTCCCGCCTCGGCCGGCCCAAGCAGCTGCTGCCGCTCGGTGGCGCGA
CGCTGCTCGACGCGACCCTG

Product: carbon monoxide dehydrogenase, large subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MTATVPIGHGRMLRKEDRRFVRGRGKYLDDIALPGMLHLAVLRSPVAHARILSIDTLAAEAHPKVKAVVTGALLAERGLA
WMPTLSGDVQAVLATDKVRFQGQEVAFVVAEDRYSARDALELIDVEYDVLPPVVDVRRALDADAPLIRDDVAGKTDNHCF
DWETGDAAATDAVFDRAEVVVRQEIVFPRVHPAPLETCGAVADYDRVEQKLTLWATTQAPHAHRTLYSMFAGLPEHKIRV
ISPDIGGGFGNKVPIYPGYVCAIVGSMVTGRPVKWTEDRTENLVASGFARDYVMQGEIAATRDGRILALRSHVLADHGAF
NGTAAPRKFPGGFFGVFTGSYDIEAAYCSMTAVHTNKAPGGVAYACSFRIAEAVYLVERMVDLLADELGIDPVELRLRNF
IRSDQFPYTSRTGWVYDSGDYATTMQEALRIAGYDELRAEQAARRAAGDGQSLMGIGVSFFTEAVGAGPRKDMDMLGLGM
ADGCELRVHPTGSAVLRIAVQTQGQGHETTFAQLVAEELGIHPENIDVVHGDTDNTPYGLGTYGSRSTPVSGAAAVIASR
RVREKARLIAAGMLEVAPDDLEWTKDAAGGRFGVRGVPGASVTIEQVAMRAHGADELPEGVEGGLDAQVSYNPDNLTYPY
GAYICVVDIDPGTAVVKVRRFVAVDDCGTRINEMIVEGQIHGGLTDGVGMALMEYIGYDEHGNCLGGSLMDYLIPTAKEV
PDWETGMTVTPSPHHPIGAKGVGESATVGSPPAVVNAVIDALAPYGVRHADMPLTPSRVWEAMHGRATPPQ

Sequences:

>Translated_791_residues
MTATVPIGHGRMLRKEDRRFVRGRGKYLDDIALPGMLHLAVLRSPVAHARILSIDTLAAEAHPKVKAVVTGALLAERGLA
WMPTLSGDVQAVLATDKVRFQGQEVAFVVAEDRYSARDALELIDVEYDVLPPVVDVRRALDADAPLIRDDVAGKTDNHCF
DWETGDAAATDAVFDRAEVVVRQEIVFPRVHPAPLETCGAVADYDRVEQKLTLWATTQAPHAHRTLYSMFAGLPEHKIRV
ISPDIGGGFGNKVPIYPGYVCAIVGSMVTGRPVKWTEDRTENLVASGFARDYVMQGEIAATRDGRILALRSHVLADHGAF
NGTAAPRKFPGGFFGVFTGSYDIEAAYCSMTAVHTNKAPGGVAYACSFRIAEAVYLVERMVDLLADELGIDPVELRLRNF
IRSDQFPYTSRTGWVYDSGDYATTMQEALRIAGYDELRAEQAARRAAGDGQSLMGIGVSFFTEAVGAGPRKDMDMLGLGM
ADGCELRVHPTGSAVLRIAVQTQGQGHETTFAQLVAEELGIHPENIDVVHGDTDNTPYGLGTYGSRSTPVSGAAAVIASR
RVREKARLIAAGMLEVAPDDLEWTKDAAGGRFGVRGVPGASVTIEQVAMRAHGADELPEGVEGGLDAQVSYNPDNLTYPY
GAYICVVDIDPGTAVVKVRRFVAVDDCGTRINEMIVEGQIHGGLTDGVGMALMEYIGYDEHGNCLGGSLMDYLIPTAKEV
PDWETGMTVTPSPHHPIGAKGVGESATVGSPPAVVNAVIDALAPYGVRHADMPLTPSRVWEAMHGRATPPQ
>Mature_790_residues
TATVPIGHGRMLRKEDRRFVRGRGKYLDDIALPGMLHLAVLRSPVAHARILSIDTLAAEAHPKVKAVVTGALLAERGLAW
MPTLSGDVQAVLATDKVRFQGQEVAFVVAEDRYSARDALELIDVEYDVLPPVVDVRRALDADAPLIRDDVAGKTDNHCFD
WETGDAAATDAVFDRAEVVVRQEIVFPRVHPAPLETCGAVADYDRVEQKLTLWATTQAPHAHRTLYSMFAGLPEHKIRVI
SPDIGGGFGNKVPIYPGYVCAIVGSMVTGRPVKWTEDRTENLVASGFARDYVMQGEIAATRDGRILALRSHVLADHGAFN
GTAAPRKFPGGFFGVFTGSYDIEAAYCSMTAVHTNKAPGGVAYACSFRIAEAVYLVERMVDLLADELGIDPVELRLRNFI
RSDQFPYTSRTGWVYDSGDYATTMQEALRIAGYDELRAEQAARRAAGDGQSLMGIGVSFFTEAVGAGPRKDMDMLGLGMA
DGCELRVHPTGSAVLRIAVQTQGQGHETTFAQLVAEELGIHPENIDVVHGDTDNTPYGLGTYGSRSTPVSGAAAVIASRR
VREKARLIAAGMLEVAPDDLEWTKDAAGGRFGVRGVPGASVTIEQVAMRAHGADELPEGVEGGLDAQVSYNPDNLTYPYG
AYICVVDIDPGTAVVKVRRFVAVDDCGTRINEMIVEGQIHGGLTDGVGMALMEYIGYDEHGNCLGGSLMDYLIPTAKEVP
DWETGMTVTPSPHHPIGAKGVGESATVGSPPAVVNAVIDALAPYGVRHADMPLTPSRVWEAMHGRATPPQ

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=805, Percent_Identity=23.7267080745342, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI91823271, Length=796, Percent_Identity=21.7336683417085, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1789230, Length=776, Percent_Identity=28.7371134020619, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1789246, Length=807, Percent_Identity=27.2614622057001, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1786478, Length=768, Percent_Identity=24.8697916666667, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=789, Percent_Identity=24.0811153358682, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84939; Mature: 84808

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATVPIGHGRMLRKEDRRFVRGRGKYLDDIALPGMLHLAVLRSPVAHARILSIDTLAAE
CCEEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHEEEEEHHHHHC
AHPKVKAVVTGALLAERGLAWMPTLSGDVQAVLATDKVRFQGQEVAFVVAEDRYSARDAL
CCCCCHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCEEECCCEEEEEEECCCCCHHHHH
ELIDVEYDVLPPVVDVRRALDADAPLIRDDVAGKTDNHCFDWETGDAAATDAVFDRAEVV
HHHCCCHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
VRQEIVFPRVHPAPLETCGAVADYDRVEQKLTLWATTQAPHAHRTLYSMFAGLPEHKIRV
HHHHHHCCCCCCCCHHHHCCHHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCCCCCEEE
ISPDIGGGFGNKVPIYPGYVCAIVGSMVTGRPVKWTEDRTENLVASGFARDYVMQGEIAA
ECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEECCCEEE
TRDGRILALRSHVLADHGAFNGTAAPRKFPGGFFGVFTGSYDIEAAYCSMTAVHTNKAPG
CCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCEECEEEEEEEEEEECCCCCC
GVAYACSFRIAEAVYLVERMVDLLADELGIDPVELRLRNFIRSDQFPYTSRTGWVYDSGD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCC
YATTMQEALRIAGYDELRAEQAARRAAGDGQSLMGIGVSFFTEAVGAGPRKDMDMLGLGM
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
ADGCELRVHPTGSAVLRIAVQTQGQGHETTFAQLVAEELGIHPENIDVVHGDTDNTPYGL
CCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
GTYGSRSTPVSGAAAVIASRRVREKARLIAAGMLEVAPDDLEWTKDAAGGRFGVRGVPGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCC
SVTIEQVAMRAHGADELPEGVEGGLDAQVSYNPDNLTYPYGAYICVVDIDPGTAVVKVRR
CHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEHEEH
FVAVDDCGTRINEMIVEGQIHGGLTDGVGMALMEYIGYDEHGNCLGGSLMDYLIPTAKEV
HEEECHHHHHHHHHHEECEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
PDWETGMTVTPSPHHPIGAKGVGESATVGSPPAVVNAVIDALAPYGVRHADMPLTPSRVW
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EAMHGRATPPQ
HHHCCCCCCCC
>Mature Secondary Structure 
TATVPIGHGRMLRKEDRRFVRGRGKYLDDIALPGMLHLAVLRSPVAHARILSIDTLAAE
CEEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHEEEEEHHHHHC
AHPKVKAVVTGALLAERGLAWMPTLSGDVQAVLATDKVRFQGQEVAFVVAEDRYSARDAL
CCCCCHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCEEECCCEEEEEEECCCCCHHHHH
ELIDVEYDVLPPVVDVRRALDADAPLIRDDVAGKTDNHCFDWETGDAAATDAVFDRAEVV
HHHCCCHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
VRQEIVFPRVHPAPLETCGAVADYDRVEQKLTLWATTQAPHAHRTLYSMFAGLPEHKIRV
HHHHHHCCCCCCCCHHHHCCHHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCCCCCEEE
ISPDIGGGFGNKVPIYPGYVCAIVGSMVTGRPVKWTEDRTENLVASGFARDYVMQGEIAA
ECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEECCCEEE
TRDGRILALRSHVLADHGAFNGTAAPRKFPGGFFGVFTGSYDIEAAYCSMTAVHTNKAPG
CCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCEECEEEEEEEEEEECCCCCC
GVAYACSFRIAEAVYLVERMVDLLADELGIDPVELRLRNFIRSDQFPYTSRTGWVYDSGD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCC
YATTMQEALRIAGYDELRAEQAARRAAGDGQSLMGIGVSFFTEAVGAGPRKDMDMLGLGM
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
ADGCELRVHPTGSAVLRIAVQTQGQGHETTFAQLVAEELGIHPENIDVVHGDTDNTPYGL
CCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
GTYGSRSTPVSGAAAVIASRRVREKARLIAAGMLEVAPDDLEWTKDAAGGRFGVRGVPGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCC
SVTIEQVAMRAHGADELPEGVEGGLDAQVSYNPDNLTYPYGAYICVVDIDPGTAVVKVRR
CHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCEEHEEH
FVAVDDCGTRINEMIVEGQIHGGLTDGVGMALMEYIGYDEHGNCLGGSLMDYLIPTAKEV
HEEECHHHHHHHHHHEECEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
PDWETGMTVTPSPHHPIGAKGVGESATVGSPPAVVNAVIDALAPYGVRHADMPLTPSRVW
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
EAMHGRATPPQ
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]