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The map label for this gene is yceI [H]

Identifier: 119356351

GI number: 119356351

Start: 563847

End: 565085

Strand: Direct

Name: yceI [H]

Synonym: Cpha266_0514

Alternate gene names: 119356351

Gene position: 563847-565085 (Clockwise)

Preceding gene: 119356350

Following gene: 119356352

Centisome position: 17.99

GC content: 48.1

Gene sequence:

>1239_bases
GTGCACAAGGAACATGCTTCGGTCAGAGATATTTTCAGTCTTCCTGTCATCGTTGCTGCGCTCGGGTATTTTGTCGATAT
CTATGACCTGGTGCTCTTCAGTATTGTACGGGTGCCGAGCCTTAAATCATTGGGCCTTGAGGGAAAACAACTGATTGACT
ACGGAGTTTATCTGCTGAATATGCAGATGATCGGCATGCTGCTTGGCGGTATTCTCTGGGGATGGCTTGGCGACAGGAAA
GGACGACTGAAAATCATGTTCGGTTCGATCCTGCTGTACTCGCTTGCCAATATTGCCAATGGTTTTGTGACCTCTTTGCC
CGCTTATGCGCTGATGCGGTTTATAGCAGGAATCGGACTTGCAGGTGAACTCGGTGCCGGCATTACCCTTGTTTCGGAGG
TTCTTCATACAAAGATCCGCGGATACGGTACCATGCTTGTTGCTTCAATCGGAGTTTCCGGCGCAATTCTTGCCAATTTT
GTTGCCAATACCTATGAGTGGCATAATGCTTTTTTTATCGGAGGCGGACTTGGATTTCTTCTTCTGTTTGCCAGAGTAAA
GGTGGCCGAGTCGGGTATGTTTAAGGCCATGGAGGAGAAAGCCGGGGTCAATCGGGGTAATATGCTCGCACTGTTTACGG
ACAGGAATCGCTTTTTTCGCTATCTAAATTCAATTCTTATCGGGGTTCCAATCTGGTTTGTTGTTGGTGTGCTTATTACC
TTTTCTCCTGAATTTGCGGTTTCCTTTGGTATTCCTGAACCGGTTTCTGCCGGAAACGCAGTCATGTTCTGCTACCTTGG
TCTGGTTTTTGGCGATTTGTCGAGCGGTCTGCTGAGTCAGCTTTTTCAGAGCAGGAGAAAGGTTATTCTTTTGTTTATGC
TTTTGTCGGTCGCTGCCGTAGCGCTTTATTTTATGCAGGGGTCGAGCAGCCCGGCTTTCTTTTATGGCGTTTGTTCCCTA
CTCGGATTTGCAAGCGGTTACTGGGCTGTTTTTGTTACTGTTGCCGCCGAACAGTTCGGAACGAATCTTCGGGCTACCGT
TGCGACAACGGTGCCGAACTTTGTTCGTGGTATGGTGGTGCCGATTACCATGCTTTTTCAATTCACGAAAGGGCTGTTCG
GCCTGGAAAACGGTGCGCTGCTTGTTGGAACGCTGTGCATCGTTGTCGCATTTTTTTCCCTTGGCGCCCTTGAGGAGACC
TTTCACAAGGATCTTGATTATTATGAAGAGTTTCTCTGA

Upstream 100 bases:

>100_bases
GAGCGGTTTATGCTATTCTGCAATAACCGATTACCCTGTTTGATTAATAACACAATCATGGTCCGGTTATATAAGCTGGA
GCTTAGAGGAGGTTTTTCTG

Downstream 100 bases:

>100_bases
CTGAACGATTTTCGGTTGTACCGTTGTTTGTTGTTTAGCTGATTTTCCTTGAGGGTTGTTGTGTGTTTATGATGGATGAG
ATTTTATGAAACACAAAAAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; N-acetylneuraminate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MHKEHASVRDIFSLPVIVAALGYFVDIYDLVLFSIVRVPSLKSLGLEGKQLIDYGVYLLNMQMIGMLLGGILWGWLGDRK
GRLKIMFGSILLYSLANIANGFVTSLPAYALMRFIAGIGLAGELGAGITLVSEVLHTKIRGYGTMLVASIGVSGAILANF
VANTYEWHNAFFIGGGLGFLLLFARVKVAESGMFKAMEEKAGVNRGNMLALFTDRNRFFRYLNSILIGVPIWFVVGVLIT
FSPEFAVSFGIPEPVSAGNAVMFCYLGLVFGDLSSGLLSQLFQSRRKVILLFMLLSVAAVALYFMQGSSSPAFFYGVCSL
LGFASGYWAVFVTVAAEQFGTNLRATVATTVPNFVRGMVVPITMLFQFTKGLFGLENGALLVGTLCIVVAFFSLGALEET
FHKDLDYYEEFL

Sequences:

>Translated_412_residues
MHKEHASVRDIFSLPVIVAALGYFVDIYDLVLFSIVRVPSLKSLGLEGKQLIDYGVYLLNMQMIGMLLGGILWGWLGDRK
GRLKIMFGSILLYSLANIANGFVTSLPAYALMRFIAGIGLAGELGAGITLVSEVLHTKIRGYGTMLVASIGVSGAILANF
VANTYEWHNAFFIGGGLGFLLLFARVKVAESGMFKAMEEKAGVNRGNMLALFTDRNRFFRYLNSILIGVPIWFVVGVLIT
FSPEFAVSFGIPEPVSAGNAVMFCYLGLVFGDLSSGLLSQLFQSRRKVILLFMLLSVAAVALYFMQGSSSPAFFYGVCSL
LGFASGYWAVFVTVAAEQFGTNLRATVATTVPNFVRGMVVPITMLFQFTKGLFGLENGALLVGTLCIVVAFFSLGALEET
FHKDLDYYEEFL
>Mature_412_residues
MHKEHASVRDIFSLPVIVAALGYFVDIYDLVLFSIVRVPSLKSLGLEGKQLIDYGVYLLNMQMIGMLLGGILWGWLGDRK
GRLKIMFGSILLYSLANIANGFVTSLPAYALMRFIAGIGLAGELGAGITLVSEVLHTKIRGYGTMLVASIGVSGAILANF
VANTYEWHNAFFIGGGLGFLLLFARVKVAESGMFKAMEEKAGVNRGNMLALFTDRNRFFRYLNSILIGVPIWFVVGVLIT
FSPEFAVSFGIPEPVSAGNAVMFCYLGLVFGDLSSGLLSQLFQSRRKVILLFMLLSVAAVALYFMQGSSSPAFFYGVCSL
LGFASGYWAVFVTVAAEQFGTNLRATVATTVPNFVRGMVVPITMLFQFTKGLFGLENGALLVGTLCIVVAFFSLGALEET
FHKDLDYYEEFL

Specific function: May Be A Sugar-Cation Symporter Involved In Sialic Acid Transport As It Is Required For Sialic Acid Uptake. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082231, Length=220, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082404, Length=203, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87081723, Length=311, Percent_Identity=26.3665594855305, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44877; Mature: 44877

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKEHASVRDIFSLPVIVAALGYFVDIYDLVLFSIVRVPSLKSLGLEGKQLIDYGVYLLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHH
MQMIGMLLGGILWGWLGDRKGRLKIMFGSILLYSLANIANGFVTSLPAYALMRFIAGIGL
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGELGAGITLVSEVLHTKIRGYGTMLVASIGVSGAILANFVANTYEWHNAFFIGGGLGFL
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECHHHHH
LLFARVKVAESGMFKAMEEKAGVNRGNMLALFTDRNRFFRYLNSILIGVPIWFVVGVLIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPEFAVSFGIPEPVSAGNAVMFCYLGLVFGDLSSGLLSQLFQSRRKVILLFMLLSVAAV
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYFMQGSSSPAFFYGVCSLLGFASGYWAVFVTVAAEQFGTNLRATVATTVPNFVRGMVV
HHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PITMLFQFTKGLFGLENGALLVGTLCIVVAFFSLGALEETFHKDLDYYEEFL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHKEHASVRDIFSLPVIVAALGYFVDIYDLVLFSIVRVPSLKSLGLEGKQLIDYGVYLLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHH
MQMIGMLLGGILWGWLGDRKGRLKIMFGSILLYSLANIANGFVTSLPAYALMRFIAGIGL
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGELGAGITLVSEVLHTKIRGYGTMLVASIGVSGAILANFVANTYEWHNAFFIGGGLGFL
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECHHHHH
LLFARVKVAESGMFKAMEEKAGVNRGNMLALFTDRNRFFRYLNSILIGVPIWFVVGVLIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPEFAVSFGIPEPVSAGNAVMFCYLGLVFGDLSSGLLSQLFQSRRKVILLFMLLSVAAV
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYFMQGSSSPAFFYGVCSLLGFASGYWAVFVTVAAEQFGTNLRATVATTVPNFVRGMVV
HHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PITMLFQFTKGLFGLENGALLVGTLCIVVAFFSLGALEETFHKDLDYYEEFL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; N-acetylneuraminate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + N-acetylneuraminate [Periplasm] = Proton [Cytoplasm] + N-acetylneuraminate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]