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The map label for this gene is murI

Identifier: 119356253

GI number: 119356253

Start: 458654

End: 459472

Strand: Reverse

Name: murI

Synonym: Cpha266_0415

Alternate gene names: 119356253

Gene position: 459472-458654 (Counterclockwise)

Preceding gene: 119356254

Following gene: 119356252

Centisome position: 14.66

GC content: 50.06

Gene sequence:

>819_bases
TTGCAGCACCATAAAGCCACACCAGAGAGCCCGATAGGAATTTTCGATTCGGGTGTCGGAGGTTTAACCGTTGTCAGGGC
GATACAGGCAGAAATGCCTGCCGAACGCATTATTTATTTTGGTGATACGGCACGCGTTCCATACGGCACAAAGTCCCCGG
CAACAATCCGCAAATACGCTCATGAAGACACGGCGATCCTTATGAGCCATCTGCCGAAAATTATTATTGTCGCCTGCAAC
ACCGTATCGGCTCTCGCTCTTGATGTCGTTGAAAAAACAGCGGGAAGCATTCCGGTTATCGGCGTTCTCAAAGCAGGTGC
TGACCTCGCCGTTCAGGTAACCCGAAACAAACATGTCGGAGTCATTGGAACGCAGGCTACCGTAAGCTCAAATGCCTACG
CTGATGCGATCACCCTGCTTGATGCGAACATAGAGGTTGTATCAAAGGCCTGTCCTCTTTTTGTTCCCCTCGCTGAAGAG
GGATTCACCGAACATGCAGCGACCCGACTTATCGCCAGTGATTACCTGGCCGCATTTGATGGACACGATATTGACACTCT
CGTGCTTGGCTGTACCCATTACCCTATTCTTCGTCATGTGATTACTGAAACCCTGCACCGTGATATCCGCATTATTGACT
CTGCAGAAGCCGTAGCGGGCAGAACGAGAAAACTTCTTGCTGACGCTAAACTCCTCAGCACAGAAAAGCATGCTCCGCCG
CCACATCTGCTCGTCAGCGATCTGCCCCAGAAGTTCAGTATGCTCTATAAACTTTTTATGGAATCGGATCTCCCTGATGT
CGAACTTGTTGAAGTATGA

Upstream 100 bases:

>100_bases
AAACTCCGTTCGGAAGGAAGAGAGTATATCGTCAGGGATGGAGATATTATCGTATTCAGATTTAACGTATAAGAGCCCAA
AAAGCACAATTTTTTCAGCA

Downstream 100 bases:

>100_bases
ACGGTAACCGTCGGAACTTTCGTTCTCGCCTGATCAAGACAGCGACCCGTCCATCCTCTTTGTTTCCGGCAATTGTTGCC
TTTTGACTCTGGACTTCTTA

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MQHHKATPESPIGIFDSGVGGLTVVRAIQAEMPAERIIYFGDTARVPYGTKSPATIRKYAHEDTAILMSHLPKIIIVACN
TVSALALDVVEKTAGSIPVIGVLKAGADLAVQVTRNKHVGVIGTQATVSSNAYADAITLLDANIEVVSKACPLFVPLAEE
GFTEHAATRLIASDYLAAFDGHDIDTLVLGCTHYPILRHVITETLHRDIRIIDSAEAVAGRTRKLLADAKLLSTEKHAPP
PHLLVSDLPQKFSMLYKLFMESDLPDVELVEV

Sequences:

>Translated_272_residues
MQHHKATPESPIGIFDSGVGGLTVVRAIQAEMPAERIIYFGDTARVPYGTKSPATIRKYAHEDTAILMSHLPKIIIVACN
TVSALALDVVEKTAGSIPVIGVLKAGADLAVQVTRNKHVGVIGTQATVSSNAYADAITLLDANIEVVSKACPLFVPLAEE
GFTEHAATRLIASDYLAAFDGHDIDTLVLGCTHYPILRHVITETLHRDIRIIDSAEAVAGRTRKLLADAKLLSTEKHAPP
PHLLVSDLPQKFSMLYKLFMESDLPDVELVEV
>Mature_272_residues
MQHHKATPESPIGIFDSGVGGLTVVRAIQAEMPAERIIYFGDTARVPYGTKSPATIRKYAHEDTAILMSHLPKIIIVACN
TVSALALDVVEKTAGSIPVIGVLKAGADLAVQVTRNKHVGVIGTQATVSSNAYADAITLLDANIEVVSKACPLFVPLAEE
GFTEHAATRLIASDYLAAFDGHDIDTLVLGCTHYPILRHVITETLHRDIRIIDSAEAVAGRTRKLLADAKLLSTEKHAPP
PHLLVSDLPQKFSMLYKLFMESDLPDVELVEV

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=230, Percent_Identity=33.0434782608696, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_CHLPD (A1BDJ6)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_910897.1
- ProteinModelPortal:   A1BDJ6
- SMR:   A1BDJ6
- STRING:   A1BDJ6
- GeneID:   4570969
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0415
- NMPDR:   fig|290317.7.peg.426
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   PRK00865
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29299; Mature: 29299

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHHKATPESPIGIFDSGVGGLTVVRAIQAEMPAERIIYFGDTARVPYGTKSPATIRKYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHH
HEDTAILMSHLPKIIIVACNTVSALALDVVEKTAGSIPVIGVLKAGADLAVQVTRNKHVG
CCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEE
VIGTQATVSSNAYADAITLLDANIEVVSKACPLFVPLAEEGFTEHAATRLIASDYLAAFD
EEECCEEECCCCHHHEEEEEECCHHHHHCCCCEEEECHHCCCHHHHHHHHHHHHHHHHCC
GHDIDTLVLGCTHYPILRHVITETLHRDIRIIDSAEAVAGRTRKLLADAKLLSTEKHAPP
CCCCHHEEECCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCCCCC
PHLLVSDLPQKFSMLYKLFMESDLPDVELVEV
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MQHHKATPESPIGIFDSGVGGLTVVRAIQAEMPAERIIYFGDTARVPYGTKSPATIRKYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHH
HEDTAILMSHLPKIIIVACNTVSALALDVVEKTAGSIPVIGVLKAGADLAVQVTRNKHVG
CCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEE
VIGTQATVSSNAYADAITLLDANIEVVSKACPLFVPLAEEGFTEHAATRLIASDYLAAFD
EEECCEEECCCCHHHEEEEEECCHHHHHCCCCEEEECHHCCCHHHHHHHHHHHHHHHHCC
GHDIDTLVLGCTHYPILRHVITETLHRDIRIIDSAEAVAGRTRKLLADAKLLSTEKHAPP
CCCCHHEEECCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCCCCC
PHLLVSDLPQKFSMLYKLFMESDLPDVELVEV
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA