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The map label for this gene is engD [H]

Identifier: 119356254

GI number: 119356254

Start: 459501

End: 460592

Strand: Reverse

Name: engD [H]

Synonym: Cpha266_0416

Alternate gene names: 119356254

Gene position: 460592-459501 (Counterclockwise)

Preceding gene: 119356257

Following gene: 119356253

Centisome position: 14.7

GC content: 48.08

Gene sequence:

>1092_bases
ATGTCACTTCGCTGCGGTATTGTCGGCTTGCCGAATGTCGGAAAATCAACGCTCTTTAACGCCATTACAGCAAAACAGGC
TGAAGCGGCCAACTATCCCTTCTGTACGATAGAACCAAATGTCGGAACGGTCCTTGTTCCCGATGAGCGGATGCAACAGA
TTGCGAATGTGGTAAAAACCCCGACACTTGTACCGGCAACCCTTGAAATTGTAGACATTGCCGGACTTGTCAAAGGAGCA
AGCAAGGGAGAGGGCCTCGGAAACCAGTTTCTTTCGCATATCCGCGAGGTCGATGCAATTGTTCATGTTGTGCGCTGTTT
CGATGACAGCAACATCATCCATGTTGAAGGAAAGATCGATCCTGCTGACGACATCGCCACCATTGAAACCGAGCTTATGC
TGGCAGATCTTGACAGCATGGAAAAAAGAATAGAGCGACTGCGAAAAAATTCGCGAAAAGAAAAAGATCTGCTGCAGTTG
GTCGATCTGGCCGAAAAAATCATCGCGGGGCTTGCAGAAGGTATTCCTGCGCGTTCCGTCATCGAAACACCTGAAGAACA
GGAGACCGCCAAACAGTTCTTTCTTCTCACGTCAAAACCAATCCTTTTTGCTGCCAACGTTGCTGAAGAGGATCTGCAAA
ACGGAAACGACTACACAAGAACAGTAGCAGAAATAGCTGAAAAAGCCGGCTCTAAAATGCTTATCATCAGTGCAAAAGCT
GAAGCGGACATCGCTGAACTTCCTGAAGAAGAGCGTCCCATGTTTCTCGAAAGTCTTGGACTCTCCATGTCGGGTCTTGA
CAGACTGATCAGAACGGCCCATGAACTGCTCGGCCTGCAAACATACTTTACAGCTGGCGAAAAAGAGGTTCATGCCTGGA
CTATCAGAAAGGGGGCTGCTGCGCCGGAAGCTGCCGGAGCAATTCACTCCGACTTCGAAAAAGGCTTCATCCGTGCGGAA
GTCATGTTTTACAAGGATCTTCTCGAACTTGGTTCAGAACAGAAGGTCAAGGAAGCTGGCAAACTCCGTTCGGAAGGAAG
AGAGTATATCGTCAGGGATGGAGATATTATCGTATTCAGATTTAACGTATAA

Upstream 100 bases:

>100_bases
TTTTATAAAAAATATTTGCTTTTTCCAAACTTATTGATTACATGTTGAAACCTTGTTTTGTAACCGGTATTTTCATCAAC
AGGTTTTTTTACTCTGTCTT

Downstream 100 bases:

>100_bases
GAGCCCAAAAAGCACAATTTTTTCAGCATTGCAGCACCATAAAGCCACACCAGAGAGCCCGATAGGAATTTTCGATTCGG
GTGTCGGAGGTTTAACCGTT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDERMQQIANVVKTPTLVPATLEIVDIAGLVKGA
SKGEGLGNQFLSHIREVDAIVHVVRCFDDSNIIHVEGKIDPADDIATIETELMLADLDSMEKRIERLRKNSRKEKDLLQL
VDLAEKIIAGLAEGIPARSVIETPEEQETAKQFFLLTSKPILFAANVAEEDLQNGNDYTRTVAEIAEKAGSKMLIISAKA
EADIAELPEEERPMFLESLGLSMSGLDRLIRTAHELLGLQTYFTAGEKEVHAWTIRKGAAAPEAAGAIHSDFEKGFIRAE
VMFYKDLLELGSEQKVKEAGKLRSEGREYIVRDGDIIVFRFNV

Sequences:

>Translated_363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDERMQQIANVVKTPTLVPATLEIVDIAGLVKGA
SKGEGLGNQFLSHIREVDAIVHVVRCFDDSNIIHVEGKIDPADDIATIETELMLADLDSMEKRIERLRKNSRKEKDLLQL
VDLAEKIIAGLAEGIPARSVIETPEEQETAKQFFLLTSKPILFAANVAEEDLQNGNDYTRTVAEIAEKAGSKMLIISAKA
EADIAELPEEERPMFLESLGLSMSGLDRLIRTAHELLGLQTYFTAGEKEVHAWTIRKGAAAPEAAGAIHSDFEKGFIRAE
VMFYKDLLELGSEQKVKEAGKLRSEGREYIVRDGDIIVFRFNV
>Mature_362_residues
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDERMQQIANVVKTPTLVPATLEIVDIAGLVKGAS
KGEGLGNQFLSHIREVDAIVHVVRCFDDSNIIHVEGKIDPADDIATIETELMLADLDSMEKRIERLRKNSRKEKDLLQLV
DLAEKIIAGLAEGIPARSVIETPEEQETAKQFFLLTSKPILFAANVAEEDLQNGNDYTRTVAEIAEKAGSKMLIISAKAE
ADIAELPEEERPMFLESLGLSMSGLDRLIRTAHELLGLQTYFTAGEKEVHAWTIRKGAAAPEAAGAIHSDFEKGFIRAEV
MFYKDLLELGSEQKVKEAGKLRSEGREYIVRDGDIIVFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=46.3414634146341, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI58761502, Length=182, Percent_Identity=46.7032967032967, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI24308117, Length=99, Percent_Identity=38.3838383838384, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=55.4945054945055, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1789574, Length=165, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=43.1693989071038, Blast_Score=314, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI17508313, Length=99, Percent_Identity=35.3535353535354, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552324, Length=134, Percent_Identity=33.5820895522388, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=42.972972972973, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=37.3015873015873, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=43.8692098092643, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=43.8692098092643, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=43.8692098092643, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=41.5384615384615, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24585318, Length=223, Percent_Identity=26.9058295964126, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129375, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39874; Mature: 39743

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDERMQQIANVVKT
CCCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
PTLVPATLEIVDIAGLVKGASKGEGLGNQFLSHIREVDAIVHVVRCFDDSNIIHVEGKID
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PADDIATIETELMLADLDSMEKRIERLRKNSRKEKDLLQLVDLAEKIIAGLAEGIPARSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IETPEEQETAKQFFLLTSKPILFAANVAEEDLQNGNDYTRTVAEIAEKAGSKMLIISAKA
HCCCCHHHHHHHHHHEECCCEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECC
EADIAELPEEERPMFLESLGLSMSGLDRLIRTAHELLGLQTYFTAGEKEVHAWTIRKGAA
CCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
APEAAGAIHSDFEKGFIRAEVMFYKDLLELGSEQKVKEAGKLRSEGREYIVRDGDIIVFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDERMQQIANVVKT
CCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
PTLVPATLEIVDIAGLVKGASKGEGLGNQFLSHIREVDAIVHVVRCFDDSNIIHVEGKID
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PADDIATIETELMLADLDSMEKRIERLRKNSRKEKDLLQLVDLAEKIIAGLAEGIPARSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IETPEEQETAKQFFLLTSKPILFAANVAEEDLQNGNDYTRTVAEIAEKAGSKMLIISAKA
HCCCCHHHHHHHHHHEECCCEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECC
EADIAELPEEERPMFLESLGLSMSGLDRLIRTAHELLGLQTYFTAGEKEVHAWTIRKGAA
CCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
APEAAGAIHSDFEKGFIRAEVMFYKDLLELGSEQKVKEAGKLRSEGREYIVRDGDIIVFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]