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The map label for this gene is ilvE [H]

Identifier: 114797299

GI number: 114797299

Start: 2465141

End: 2465968

Strand: Reverse

Name: ilvE [H]

Synonym: HNE_2367

Alternate gene names: 114797299

Gene position: 2465968-2465141 (Counterclockwise)

Preceding gene: 114798283

Following gene: 114797314

Centisome position: 66.56

GC content: 64.73

Gene sequence:

>828_bases
ATGATCCGGTTCAGCCAACCCGGCGCGGCCCCTGAAAACACAGAGCTTTTTGATCTCACCGATCGCGGCCTGCTGCTGGC
CGATGGTGTGTTCGATACCTCGCGCGTTGTGGGTGGACGGATCATCCAGAAGCGCGCGCATTTGATGCGTCTGGCGTCCG
ACGCTGCGGCCCTCGGGGTCGGCGCCAACCTGTCAGAGCTTGACGCTCTGGCGCAGGAAGCCGTTCCGCAGAATGCAAAT
GGCGCCTTGCGTCTCACCGTCACGCGTGGCCCCGGCGGGCGCGGTCTGGCGGGCGCGGCAACCGGGGCGGCAACCCTGCT
GGCGCGCTTTTCTCCGATGGACGTTGCTTTTCCCATGCCGCCCGTCCGGCTGCGGATCAGCAATATCCGGCGCAATCCCA
CCTCTCCCTCGGCGCGCCACAAGACCCTGTCCTATACGGACAATATCATGGCGCTGCGCGAGGCGATGGCGATGGGATAT
GACGAGGCCCTGTTGCTTTCGCCCGAAGGCCGGGTCGCCTGCGCCTCGGCGGCGAATGTTTTTGCCCTGTTTGGAAACCT
GCTGGTCACCCCGCCGCTGTCAGAAGGCGTGTTGCCGGGCGTTGTGCGCGGCTGGCTGATCGGCGCTGCGCGGGAGGCAG
GCCTTGAGACCGCGCAGGAAAGCCTGACGCCAGAGCGTCTGTCCGAGGCCGACAGCATTTTCCTGACCAACAGCCTGCGC
ATCTTTCAGCCTGTCAGCGAGTTTGCCGGGCAGGCATTCGAAACGGAATTGCCCGCCGCCCTGATCGGCCTCGGCAAAAC
CCTTCTGGAGGGAGGTTTCGATGATTGA

Upstream 100 bases:

>100_bases
CCATCTACGGCATCCAGTTTCATCCAGAATCCATCCTCACCCAGCATGGCCCGGCCCTGCTTCAGAACTTCCTCAACATC
GCCCGCGCCTGGAGGCAGAC

Downstream 100 bases:

>100_bases
TACTGAGCGGCGCGACAGGACACTCGCCCGTGTGCGCAACGAACCTGTCATCATGGGCATTCTCAATGTGACGCCCGACA
GCTTCTCCGATGGCGGACGG

Product: class IV aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MIRFSQPGAAPENTELFDLTDRGLLLADGVFDTSRVVGGRIIQKRAHLMRLASDAAALGVGANLSELDALAQEAVPQNAN
GALRLTVTRGPGGRGLAGAATGAATLLARFSPMDVAFPMPPVRLRISNIRRNPTSPSARHKTLSYTDNIMALREAMAMGY
DEALLLSPEGRVACASAANVFALFGNLLVTPPLSEGVLPGVVRGWLIGAAREAGLETAQESLTPERLSEADSIFLTNSLR
IFQPVSEFAGQAFETELPAALIGLGKTLLEGGFDD

Sequences:

>Translated_275_residues
MIRFSQPGAAPENTELFDLTDRGLLLADGVFDTSRVVGGRIIQKRAHLMRLASDAAALGVGANLSELDALAQEAVPQNAN
GALRLTVTRGPGGRGLAGAATGAATLLARFSPMDVAFPMPPVRLRISNIRRNPTSPSARHKTLSYTDNIMALREAMAMGY
DEALLLSPEGRVACASAANVFALFGNLLVTPPLSEGVLPGVVRGWLIGAAREAGLETAQESLTPERLSEADSIFLTNSLR
IFQPVSEFAGQAFETELPAALIGLGKTLLEGGFDD
>Mature_275_residues
MIRFSQPGAAPENTELFDLTDRGLLLADGVFDTSRVVGGRIIQKRAHLMRLASDAAALGVGANLSELDALAQEAVPQNAN
GALRLTVTRGPGGRGLAGAATGAATLLARFSPMDVAFPMPPVRLRISNIRRNPTSPSARHKTLSYTDNIMALREAMAMGY
DEALLLSPEGRVACASAANVFALFGNLLVTPPLSEGVLPGVVRGWLIGAAREAGLETAQESLTPERLSEADSIFLTNSLR
IFQPVSEFAGQAFETELPAALIGLGKTLLEGGFDD

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=254, Percent_Identity=26.7716535433071, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI48994963, Length=117, Percent_Identity=29.9145299145299, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 28922; Mature: 28922

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFSQPGAAPENTELFDLTDRGLLLADGVFDTSRVVGGRIIQKRAHLMRLASDAAALGV
CCEECCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GANLSELDALAQEAVPQNANGALRLTVTRGPGGRGLAGAATGAATLLARFSPMDVAFPMP
CCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCC
PVRLRISNIRRNPTSPSARHKTLSYTDNIMALREAMAMGYDEALLLSPEGRVACASAANV
CCEEEEEHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHHHH
FALFGNLLVTPPLSEGVLPGVVRGWLIGAAREAGLETAQESLTPERLSEADSIFLTNSLR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCHH
IFQPVSEFAGQAFETELPAALIGLGKTLLEGGFDD
HHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRFSQPGAAPENTELFDLTDRGLLLADGVFDTSRVVGGRIIQKRAHLMRLASDAAALGV
CCEECCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GANLSELDALAQEAVPQNANGALRLTVTRGPGGRGLAGAATGAATLLARFSPMDVAFPMP
CCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEECCCC
PVRLRISNIRRNPTSPSARHKTLSYTDNIMALREAMAMGYDEALLLSPEGRVACASAANV
CCEEEEEHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHHHH
FALFGNLLVTPPLSEGVLPGVVRGWLIGAAREAGLETAQESLTPERLSEADSIFLTNSLR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCHH
IFQPVSEFAGQAFETELPAALIGLGKTLLEGGFDD
HHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]