Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 114798283

GI number: 114798283

Start: 2465965

End: 2466549

Strand: Reverse

Name: pabA [H]

Synonym: HNE_2368

Alternate gene names: 114798283

Gene position: 2466549-2465965 (Counterclockwise)

Preceding gene: 114799322

Following gene: 114797299

Centisome position: 66.57

GC content: 62.91

Gene sequence:

>585_bases
ATGATCCTGATGCTGAACAACCGGGACAGTTTCGTATTCAATCTTGCCCGCTATTTCAGCGAGCTGGGCTGTGAGATGAA
TGTGGTAGACAGTGATCAGATCGCGGTCACAGAGATTGAGGCGCTGGCGCCCGAAGCGCTGGTGATTTCGCCGGGACCCT
GCACCCCGGCGGAGGCTGGCATTTCCATCCAGGCAATTAACGCCTTGGGTGCGCGCCTGCCGATCCTCGGCGTCTGCCTG
GGCCATCAGGCGATTGCGGCGGCCCATGGCTGGCCGGTGACGCATGCCCGGTCGCCCGCCCATGGCCGCGCAGCGCGCAT
CACACATACCGGCCAACGGCTGTTTGCGGGGCTGCCCGGCGCCTTTGAGGTCGGTCTCTATCACTCTCTCATCGCCGCTG
CGCCAGATGCGCCGGGGCCGCTGGTCATTGACGCGGTCTCTCCCTCAGGTGAAGTGATGGCGTTATCGCACCCGGAGAAG
CCCATCTACGGCATCCAGTTTCATCCAGAATCCATCCTCACCCAGCATGGCCCGGCCCTGCTTCAGAACTTCCTCAACAT
CGCCCGCGCCTGGAGGCAGACATGA

Upstream 100 bases:

>100_bases
CAGGCATCACGCTTCTGTCTGATCCGGAGGCGGAGTATGACGAAATCAGCCTGAAAGCCGAACGCATCATGGGCGATACA
CGCGGTGGGGTGGCCACGTC

Downstream 100 bases:

>100_bases
TCCGGTTCAGCCAACCCGGCGCGGCCCCTGAAAACACAGAGCTTTTTGATCTCACCGATCGCGGCCTGCTGCTGGCCGAT
GGTGTGTTCGATACCTCGCG

Product: 4-amino-4-deoxychorismate synthase, glutamine amidotransferase subunit

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MILMLNNRDSFVFNLARYFSELGCEMNVVDSDQIAVTEIEALAPEALVISPGPCTPAEAGISIQAINALGARLPILGVCL
GHQAIAAAHGWPVTHARSPAHGRAARITHTGQRLFAGLPGAFEVGLYHSLIAAAPDAPGPLVIDAVSPSGEVMALSHPEK
PIYGIQFHPESILTQHGPALLQNFLNIARAWRQT

Sequences:

>Translated_194_residues
MILMLNNRDSFVFNLARYFSELGCEMNVVDSDQIAVTEIEALAPEALVISPGPCTPAEAGISIQAINALGARLPILGVCL
GHQAIAAAHGWPVTHARSPAHGRAARITHTGQRLFAGLPGAFEVGLYHSLIAAAPDAPGPLVIDAVSPSGEVMALSHPEK
PIYGIQFHPESILTQHGPALLQNFLNIARAWRQT
>Mature_194_residues
MILMLNNRDSFVFNLARYFSELGCEMNVVDSDQIAVTEIEALAPEALVISPGPCTPAEAGISIQAINALGARLPILGVCL
GHQAIAAAHGWPVTHARSPAHGRAARITHTGQRLFAGLPGAFEVGLYHSLIAAAPDAPGPLVIDAVSPSGEVMALSHPEK
PIYGIQFHPESILTQHGPALLQNFLNIARAWRQT

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=47.3118279569892, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1787517, Length=195, Percent_Identity=43.0769230769231, Blast_Score=133, Evalue=6e-33,
Organism=Escherichia coli, GI1786215, Length=184, Percent_Identity=24.4565217391304, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=195, Percent_Identity=34.3589743589744, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=29.8578199052133, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 20561; Mature: 20561

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMLNNRDSFVFNLARYFSELGCEMNVVDSDQIAVTEIEALAPEALVISPGPCTPAEAG
CEEEEECCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEHHHHCCCEEEECCCCCCCHHCC
ISIQAINALGARLPILGVCLGHQAIAAAHGWPVTHARSPAHGRAARITHTGQRLFAGLPG
EEEEEHHHHCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCC
AFEVGLYHSLIAAAPDAPGPLVIDAVSPSGEVMALSHPEKPIYGIQFHPESILTQHGPAL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LQNFLNIARAWRQT
HHHHHHHHHHHHCC
>Mature Secondary Structure
MILMLNNRDSFVFNLARYFSELGCEMNVVDSDQIAVTEIEALAPEALVISPGPCTPAEAG
CEEEEECCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEHHHHCCCEEEECCCCCCCHHCC
ISIQAINALGARLPILGVCLGHQAIAAAHGWPVTHARSPAHGRAARITHTGQRLFAGLPG
EEEEEHHHHCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCC
AFEVGLYHSLIAAAPDAPGPLVIDAVSPSGEVMALSHPEKPIYGIQFHPESILTQHGPAL
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LQNFLNIARAWRQT
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]