Click here to switch to the map view.

The map label for this gene is ina [H]

Identifier: 113968470

GI number: 113968470

Start: 139356

End: 142166

Strand: Direct

Name: ina [H]

Synonym: Shewmr4_0125

Alternate gene names: 113968470

Gene position: 139356-142166 (Clockwise)

Preceding gene: 113968469

Following gene: 113968472

Centisome position: 2.96

GC content: 49.88

Gene sequence:

>2811_bases
ATGCGAAGTTCAAAAAGTATCACAGCGTTAGGATTGATGTTGGCCTTGCTGAGTGGCGCAAGTATTGCGGCGCCCAATCA
TACGCCAGCGGATGCGGGTGTCATTAATAAAGAAAGGATCCTTTATTGGTTGATCAAGCGGGGTGAAGTCTCCGCCGATG
CTAGCGACAGCGTTAAGCAAGCGGCCGTTGAAGCCTATATTGCCCGTGCCAGTCTAGCTCAGCCCAAAGAGCCGAGAATG
GTGATTGAGGCCGAACATGACAGACTGCAGAAAGTAAAATCGACAGCGATGATGCGCGCACCCGCACAGCGGGTGTTAGG
GGATGCAGACGTGACCAAAACGGTGAAAGTATTAACCGTACTGATTGATTTTCCTGATTTAAAGTATAACAACAATGGTT
TGACGGCGAGTGATACCGACATGTATTACTCAAGTTACCCCGCGTCTCACTACAAGAATTTACTCTTCTCCACCACTGGC
TTTACGGGCCCGCAAGGTCAGACCTTAGACTCCGCCTATCAATATTACCAAGCCGTTTCAGGCAAGACTTTCTTCTTTAC
TGGCGACGTGAAAGGTTGGTACACAGCAAGCCAAAATGCCGATTACTATGGCGCCAATAATGCTGGTAGGGGGAGTGATG
CTAATGTGACTGAGCTGGTTAAAGAGGCCGTTAGCCAAGCGGTTGCCAATATGTCGGCGGCGGAACTCGCAACCTATGAT
ATTGAAGATCCATACGATTTAAATAATAACGGCAATTTAGATGAACCCGATGGCATTATTGACCATGTGATGATTTTCCA
CTCCAGTATTGGTGAAGAAACTGGCGGCGGTAAATTAGGGGACAACGCGATTTGGTCGCACCGTTATTATGTTGACCAGA
GCACGCAAGGTTATAGCCTACCTGGGTCGACCAAAAAACTCTTCGGTTACACCATTCAACCAATCGATGCGGCGACAGGG
GTCTGTACCCATGAGTTTGGCCACGATCTGGGCTTGCCCGATGAATATGACACGACGGAGAACACCAATAAAGATGGTTC
TCCCGTGGGTGCTTGGTCTTTAATGTCTTCGGGTAGTTGGACTGGCGCCATCCCTGGTACTAAACCTAGCGGTTTTAGCC
CCTACGCGCGCTCCTATTTACAGGAAAAATATAAAGGTAAATGGCTGAATGAGCGTGAAATCAGCTTAGACAGTATTCCT
AAATCTGGTATGGAAGTGACACTGAATCAGGCGTCAAATCAAGAAGTAGTGAACCAGGTATCGATTCAGCTTCCTGCGAC
ACAAATTGCCTTTAAAACACCTTATGAAGGGAGCTATCAGTATTACTCCGGCCAAGGAAACATGCTGAGCAATAGCATGA
GCTTTACGGCAAACTTACCGGCGACGAGTGAAAAACTCACGCTTGCGATGCAGGCGAGTTGGGAGGTTGAAGCCGACTAC
GACTATATGCAGGTCAAAGTGAACGGTGTGGCGATTGCGGGCAATTACACTAAGTCCGTCAACGCGATTAACAGCGCTCG
ACATATTATTACGGGTAAATCATCGAGCATTTCGGCAGCGGTCGGCAGCGACGCTTGGGTGGGGTTGGAATATGATCTGT
CAGCCTACGCTGGCAAAGCTGTGACGATTGAATTTACCTATGTGACCGATGAGGGGGTGAGCGAATCAGGTATCACTATC
GACAATATCAGTATCAAACAAGGTGCAGCTGAGCTGTATGCCGATAATGCTGAGGTTGCGGGTCAAGCGACTCTGGCTGG
TTACAGTCGGATCACCAATACGCGCCCAGGTGCAGCATCCCGCTACTTAATCCAATTACGTAGTCACAATGGTGTCGATG
CCGGATTAAAGAATGAAGGTTTTGATCCCGGCGTACTCCTGTGGTTAGAGGATTTTAGTTATTACGATAACAATGTGTCT
GATCATCCCGGCCGAAGCTTAATAGGCGTGATTGATGCGGATCAGAACATGATTGGCAACAACTCGACCGATGTACAAAT
CCGCGATGCGGCCTTCAGCCTAGTCAGACAAACGGCTTATACTGGCGACACTAACCTCGAACCTACGAGTCTGTTTGACG
ATAGTTTCGATTACAGTGCACCGCTCCAACCACAGTCGGGGATGGTGCTGCAAAAGCTGGGCTTGACGATGCAAGTGGTC
TCTCAAGCCAGTGACAACAGCACCGCGGTGATCCGTTTAGCCAATGCGAATGCCGATCCCGCATTAACGCCCTTAACGGC
AGCGATCAATCTAAGCCAAAATGGCTTAACAGCCTCTGTTACTGCAGTGGTTGATGGTGGCGAAGGCGCATACACTTATG
CTTGGGATTTTGGTGTTGCGGGAGCGACCAGCACTTCAGCGTCGGCGACTTATACCTACGCGAACGCAGGAACCTATACG
CTGACCTTAACGGTAACCGATGCCAAAGGCACAATTGCTACTGCCACTAAAACGCTTGTGATGAGCTTGCCCTTAACCGC
TGGTTTTAGTGCCAGTGCCAACCAGCTTACGGTGAACTTTAGCAATACCTCGGCAGGTGGTGTTGGTAGCCGCAGCTATA
CATGGAACTTTGGCGATGGCACCTCAAGCACCTCGGTATCGCCATCCCATACTTATACTCGCGCGGGCACTTACCTTGTC
ACACTGACAGTGAAAGATACCCAAAACGCTACAGCAAGCAGCAGCTCAAGCGTTACCGTGTCTGAGCCAACGACACCGGG
TGAAACCCCAAGTAGTGGCGGTGGTGGCAGTCTAAGCTGGCTGAGCCTGATGTTGCTCGGTGGTTTTGCGTGGCGCCGCC
AGCGTCAATAA

Upstream 100 bases:

>100_bases
ACACCGCGAGCCGCTAAAAACAAACTTGCCATAGAGCAAATTGGCACTAGCCTTTAAAAATAGCTTGGTTACAGCGCACA
TTGTGACGGAAGGAAGAGTA

Downstream 100 bases:

>100_bases
GCGGATGTGCTAACGAAAAATGCCTCTGATATAGAGGCATTTTTGTTTTTAGCACTTGAGTTAGTCTAGTTTTAACTTAG
CCATCGCTTGTACTGCGGCC

Product: peptidase M6, immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 936; Mature: 936

Protein sequence:

>936_residues
MRSSKSITALGLMLALLSGASIAAPNHTPADAGVINKERILYWLIKRGEVSADASDSVKQAAVEAYIARASLAQPKEPRM
VIEAEHDRLQKVKSTAMMRAPAQRVLGDADVTKTVKVLTVLIDFPDLKYNNNGLTASDTDMYYSSYPASHYKNLLFSTTG
FTGPQGQTLDSAYQYYQAVSGKTFFFTGDVKGWYTASQNADYYGANNAGRGSDANVTELVKEAVSQAVANMSAAELATYD
IEDPYDLNNNGNLDEPDGIIDHVMIFHSSIGEETGGGKLGDNAIWSHRYYVDQSTQGYSLPGSTKKLFGYTIQPIDAATG
VCTHEFGHDLGLPDEYDTTENTNKDGSPVGAWSLMSSGSWTGAIPGTKPSGFSPYARSYLQEKYKGKWLNEREISLDSIP
KSGMEVTLNQASNQEVVNQVSIQLPATQIAFKTPYEGSYQYYSGQGNMLSNSMSFTANLPATSEKLTLAMQASWEVEADY
DYMQVKVNGVAIAGNYTKSVNAINSARHIITGKSSSISAAVGSDAWVGLEYDLSAYAGKAVTIEFTYVTDEGVSESGITI
DNISIKQGAAELYADNAEVAGQATLAGYSRITNTRPGAASRYLIQLRSHNGVDAGLKNEGFDPGVLLWLEDFSYYDNNVS
DHPGRSLIGVIDADQNMIGNNSTDVQIRDAAFSLVRQTAYTGDTNLEPTSLFDDSFDYSAPLQPQSGMVLQKLGLTMQVV
SQASDNSTAVIRLANANADPALTPLTAAINLSQNGLTASVTAVVDGGEGAYTYAWDFGVAGATSTSASATYTYANAGTYT
LTLTVTDAKGTIATATKTLVMSLPLTAGFSASANQLTVNFSNTSAGGVGSRSYTWNFGDGTSSTSVSPSHTYTRAGTYLV
TLTVKDTQNATASSSSSVTVSEPTTPGETPSSGGGGSLSWLSLMLLGGFAWRRQRQ

Sequences:

>Translated_936_residues
MRSSKSITALGLMLALLSGASIAAPNHTPADAGVINKERILYWLIKRGEVSADASDSVKQAAVEAYIARASLAQPKEPRM
VIEAEHDRLQKVKSTAMMRAPAQRVLGDADVTKTVKVLTVLIDFPDLKYNNNGLTASDTDMYYSSYPASHYKNLLFSTTG
FTGPQGQTLDSAYQYYQAVSGKTFFFTGDVKGWYTASQNADYYGANNAGRGSDANVTELVKEAVSQAVANMSAAELATYD
IEDPYDLNNNGNLDEPDGIIDHVMIFHSSIGEETGGGKLGDNAIWSHRYYVDQSTQGYSLPGSTKKLFGYTIQPIDAATG
VCTHEFGHDLGLPDEYDTTENTNKDGSPVGAWSLMSSGSWTGAIPGTKPSGFSPYARSYLQEKYKGKWLNEREISLDSIP
KSGMEVTLNQASNQEVVNQVSIQLPATQIAFKTPYEGSYQYYSGQGNMLSNSMSFTANLPATSEKLTLAMQASWEVEADY
DYMQVKVNGVAIAGNYTKSVNAINSARHIITGKSSSISAAVGSDAWVGLEYDLSAYAGKAVTIEFTYVTDEGVSESGITI
DNISIKQGAAELYADNAEVAGQATLAGYSRITNTRPGAASRYLIQLRSHNGVDAGLKNEGFDPGVLLWLEDFSYYDNNVS
DHPGRSLIGVIDADQNMIGNNSTDVQIRDAAFSLVRQTAYTGDTNLEPTSLFDDSFDYSAPLQPQSGMVLQKLGLTMQVV
SQASDNSTAVIRLANANADPALTPLTAAINLSQNGLTASVTAVVDGGEGAYTYAWDFGVAGATSTSASATYTYANAGTYT
LTLTVTDAKGTIATATKTLVMSLPLTAGFSASANQLTVNFSNTSAGGVGSRSYTWNFGDGTSSTSVSPSHTYTRAGTYLV
TLTVKDTQNATASSSSSVTVSEPTTPGETPSSGGGGSLSWLSLMLLGGFAWRRQRQ
>Mature_936_residues
MRSSKSITALGLMLALLSGASIAAPNHTPADAGVINKERILYWLIKRGEVSADASDSVKQAAVEAYIARASLAQPKEPRM
VIEAEHDRLQKVKSTAMMRAPAQRVLGDADVTKTVKVLTVLIDFPDLKYNNNGLTASDTDMYYSSYPASHYKNLLFSTTG
FTGPQGQTLDSAYQYYQAVSGKTFFFTGDVKGWYTASQNADYYGANNAGRGSDANVTELVKEAVSQAVANMSAAELATYD
IEDPYDLNNNGNLDEPDGIIDHVMIFHSSIGEETGGGKLGDNAIWSHRYYVDQSTQGYSLPGSTKKLFGYTIQPIDAATG
VCTHEFGHDLGLPDEYDTTENTNKDGSPVGAWSLMSSGSWTGAIPGTKPSGFSPYARSYLQEKYKGKWLNEREISLDSIP
KSGMEVTLNQASNQEVVNQVSIQLPATQIAFKTPYEGSYQYYSGQGNMLSNSMSFTANLPATSEKLTLAMQASWEVEADY
DYMQVKVNGVAIAGNYTKSVNAINSARHIITGKSSSISAAVGSDAWVGLEYDLSAYAGKAVTIEFTYVTDEGVSESGITI
DNISIKQGAAELYADNAEVAGQATLAGYSRITNTRPGAASRYLIQLRSHNGVDAGLKNEGFDPGVLLWLEDFSYYDNNVS
DHPGRSLIGVIDADQNMIGNNSTDVQIRDAAFSLVRQTAYTGDTNLEPTSLFDDSFDYSAPLQPQSGMVLQKLGLTMQVV
SQASDNSTAVIRLANANADPALTPLTAAINLSQNGLTASVTAVVDGGEGAYTYAWDFGVAGATSTSASATYTYANAGTYT
LTLTVTDAKGTIATATKTLVMSLPLTAGFSASANQLTVNFSNTSAGGVGSRSYTWNFGDGTSSTSVSPSHTYTRAGTYLV
TLTVKDTQNATASSSSSVTVSEPTTPGETPSSGGGGSLSWLSLMLLGGFAWRRQRQ

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 99639; Mature: 99639

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50093 PKD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSKSITALGLMLALLSGASIAAPNHTPADAGVINKERILYWLIKRGEVSADASDSVKQ
CCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
AAVEAYIARASLAQPKEPRMVIEAEHDRLQKVKSTAMMRAPAQRVLGDADVTKTVKVLTV
HHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHEEEEEE
LIDFPDLKYNNNGLTASDTDMYYSSYPASHYKNLLFSTTGFTGPQGQTLDSAYQYYQAVS
EEECCCCEECCCCCCCCCCCCEECCCCHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHC
GKTFFFTGDVKGWYTASQNADYYGANNAGRGSDANVTELVKEAVSQAVANMSAAELATYD
CCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEC
IEDPYDLNNNGNLDEPDGIIDHVMIFHSSIGEETGGGKLGDNAIWSHRYYVDQSTQGYSL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
PGSTKKLFGYTIQPIDAATGVCTHEFGHDLGLPDEYDTTENTNKDGSPVGAWSLMSSGSW
CCCCHHHCCEEECCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
TGAIPGTKPSGFSPYARSYLQEKYKGKWLNEREISLDSIPKSGMEVTLNQASNQEVVNQV
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHE
SIQLPATQIAFKTPYEGSYQYYSGQGNMLSNSMSFTANLPATSEKLTLAMQASWEVEADY
EEECCCEEEEEECCCCCCEEEECCCCCEEECCCEEEEECCCCCCEEEEEEEECEEEECCC
DYMQVKVNGVAIAGNYTKSVNAINSARHIITGKSSSISAAVGSDAWVGLEYDLSAYAGKA
CEEEEEEEEEEEECCCCHHHHHHHCCCEEEECCCCCCEEECCCCEEEEEEECHHHHCCCE
VTIEFTYVTDEGVSESGITIDNISIKQGAAELYADNAEVAGQATLAGYSRITNTRPGAAS
EEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCC
RYLIQLRSHNGVDAGLKNEGFDPGVLLWLEDFSYYDNNVSDHPGRSLIGVIDADQNMIGN
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEECCCCCCCC
NSTDVQIRDAAFSLVRQTAYTGDTNLEPTSLFDDSFDYSAPLQPQSGMVLQKLGLTMQVV
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHH
SQASDNSTAVIRLANANADPALTPLTAAINLSQNGLTASVTAVVDGGEGAYTYAWDFGVA
HCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCC
GATSTSASATYTYANAGTYTLTLTVTDAKGTIATATKTLVMSLPLTAGFSASANQLTVNF
CCCCCCCCEEEEEECCCEEEEEEEEECCCCCEEHHHEEEEEECCCCCCCCCCCCEEEEEE
SNTSAGGVGSRSYTWNFGDGTSSTSVSPSHTYTRAGTYLVTLTVKDTQNATASSSSSVTV
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCCCCCCCCEEEE
SEPTTPGETPSSGGGGSLSWLSLMLLGGFAWRRQRQ
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSSKSITALGLMLALLSGASIAAPNHTPADAGVINKERILYWLIKRGEVSADASDSVKQ
CCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
AAVEAYIARASLAQPKEPRMVIEAEHDRLQKVKSTAMMRAPAQRVLGDADVTKTVKVLTV
HHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCHHHHHEEEEEE
LIDFPDLKYNNNGLTASDTDMYYSSYPASHYKNLLFSTTGFTGPQGQTLDSAYQYYQAVS
EEECCCCEECCCCCCCCCCCCEECCCCHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHC
GKTFFFTGDVKGWYTASQNADYYGANNAGRGSDANVTELVKEAVSQAVANMSAAELATYD
CCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEC
IEDPYDLNNNGNLDEPDGIIDHVMIFHSSIGEETGGGKLGDNAIWSHRYYVDQSTQGYSL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
PGSTKKLFGYTIQPIDAATGVCTHEFGHDLGLPDEYDTTENTNKDGSPVGAWSLMSSGSW
CCCCHHHCCEEECCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
TGAIPGTKPSGFSPYARSYLQEKYKGKWLNEREISLDSIPKSGMEVTLNQASNQEVVNQV
EECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHE
SIQLPATQIAFKTPYEGSYQYYSGQGNMLSNSMSFTANLPATSEKLTLAMQASWEVEADY
EEECCCEEEEEECCCCCCEEEECCCCCEEECCCEEEEECCCCCCEEEEEEEECEEEECCC
DYMQVKVNGVAIAGNYTKSVNAINSARHIITGKSSSISAAVGSDAWVGLEYDLSAYAGKA
CEEEEEEEEEEEECCCCHHHHHHHCCCEEEECCCCCCEEECCCCEEEEEEECHHHHCCCE
VTIEFTYVTDEGVSESGITIDNISIKQGAAELYADNAEVAGQATLAGYSRITNTRPGAAS
EEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCEEHHHHHHHCCCCCCCCC
RYLIQLRSHNGVDAGLKNEGFDPGVLLWLEDFSYYDNNVSDHPGRSLIGVIDADQNMIGN
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEECCCCCCCC
NSTDVQIRDAAFSLVRQTAYTGDTNLEPTSLFDDSFDYSAPLQPQSGMVLQKLGLTMQVV
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHH
SQASDNSTAVIRLANANADPALTPLTAAINLSQNGLTASVTAVVDGGEGAYTYAWDFGVA
HCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCC
GATSTSASATYTYANAGTYTLTLTVTDAKGTIATATKTLVMSLPLTAGFSASANQLTVNF
CCCCCCCCEEEEEECCCEEEEEEEEECCCCCEEHHHEEEEEECCCCCCCCCCCCEEEEEE
SNTSAGGVGSRSYTWNFGDGTSSTSVSPSHTYTRAGTYLVTLTVKDTQNATASSSSSVTV
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCCCCCCCCEEEE
SEPTTPGETPSSGGGGSLSWLSLMLLGGFAWRRQRQ
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]