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The map label for this gene is btuB [H]

Identifier: 113968469

GI number: 113968469

Start: 136100

End: 138955

Strand: Direct

Name: btuB [H]

Synonym: Shewmr4_0124

Alternate gene names: 113968469

Gene position: 136100-138955 (Clockwise)

Preceding gene: 113968465

Following gene: 113968470

Centisome position: 2.89

GC content: 41.63

Gene sequence:

>2856_bases
ATGGCTATTGAGTCATACTTAACCAAGGCGGTGCGAGTAGCTCTCGTTGCGAGTACTGCAAGTATTATGTTTGGGGCTTC
TGCATATGCGGCAGAAGATGCTCCGGGTGCAAACAAGAAAGAAGAAGTTGAAAGAATTGCAGTTACAGGTTCGCGTATCA
TTCGTGAAGGGGCCATTGCTCCAACTCCAGTTACGGTTATCACAGGCGAGGAGTTACTCTCTACTGGTGTTACAAACATT
GGTGAGGCGTTAAACCAATTACCCGCTTTAGGTAGTACATATTCGCTTGCTAACTCTGGTCGTTTTATTGGTACTTCAGG
TCTTAACTTGCTTGACCTTCGTAACATGGGGACTGATAGAACTTTAGTGCTTGTTGATGGCCGCCGCCATGTCGCGAGCT
CTTCTGGCACATCTTCCGTTGACATTAACACTATTCCTAGTACATGGGTTGAAAAAGTAGAAGTTATTACTGGTGGTGCA
TCTGCTATTTATGGTGCCGATGCAGTAACTGGTGTTGTTAACTTTATTTTAAAGAAACATGTAACTGGATTAGATGTCTC
TACTACGTTAGGAACTGCTGAAGATAGCAATTTTACTAAAAAGCGTTTTTCAGTTTCTTACGGTACCGACTTTGACAATG
GTAGAGGTAATATCGCTGGTGCTTTTGAGTATAGCGGTCAAAACCAGCTAAAGGCATTCGATCGAGATCAAACCGCGACT
TCATTTGCGTCCATCACAAACTCCAATCGTCCTAATGGTGATGAAAACGACCCAGCTTATCCTGATAAAATCTTAACTCC
AAATGCTGGACATTATCGAATCAGCAACGCTGGAACATTTAATCTAAATGGCTGGAAAACCTTTAATCCAGATGGCTCAA
TTAAAGATGTTTATATTGGACCTAATTCAGATGGTGGTTACTGTGCAGACTGTGATTACACTAACTTGAACCAGTTCGTT
GAGTTGCAGCCGGAGTTTGATCGTTATAATTTCAACGTCAAAGGTAACTATGCTATCTCTGACGATATGAATTTCTACGC
AGAAGGGAAATATGTGAGAAGCAAGTCTCATGATATGTTCCAACCAGCGTTTTTCTTCTTTAATCCTGTGAACACAATCA
GTATTGATAACGCATTCATTCAAGATGACCTGCGTGACTTAATGACTGCCAATGGTAAAACAAGCTTAACTATCAACCGA
TTCACGACGGATTTAGGTTTGCGTCTTGAAGATGATACCCGTGAAACACAAAGATATGTTGTTGGGTTGGAAGGCAATCT
CCTTGAAGATTGGTCATACGACGTCTTTGCTACGTACGGGCAAACCGATCTTGAGCGTGTAAACCGTAATAACCTAGTTT
ATGCGAATTATGAAAATGCTTTAGATTCTATTCTTGTTGATGGCGTTGCAGTTTGCCGTGATGAGGCTGCAAGAGCTGCT
GGTTGCGTGCCTGTAAACATTTTTGGTGATGGTCAAGCAAGCCAGGGTGCGCGTGATTACATCAACACCACGTCTACAGG
TTCTTCTGTTATTAAGCAAACTGTGTTGGGTGGTTCTGTAACTAATTCTGCATTGTTTGATTTACCAGCAGGCGCAGTTG
GTTTCTCTGCTGGTGTTGAATACCGTAAAGAAGAAAGCGAAGTCTTTGAACCTGATAATGCTGAAGGTACCTTCTTCAAC
GTGTTAGGTGAAGATAAAGGCGACTTTGATGTTAAAGAAGTATTTGCAGAGATCAGTGTACCGCTGTTGAGTGATCTTCC
ATTAGTTCGCCAGTTAGACGCTGAATTGGCTGCACGTTATGCGAATTACAGTACAATTGGAAGCGCTACAACATGGAAAG
CGGGTTTGAGTTGGGAGGTCTATGATGATCTTCGTATTCGATCTACTTACTCTGAGGCTATTCGTGCGCCTAACATTAGC
GAGTTGTTTGGTGCGCAAAGTCAAAACTTTTTCAACGTAGATGACTCTTGTAAATCTTCTGAGCTTGATAATTTAGCTAA
TTCAGAGCTTCGTCGTCAGAACTGTGCGGCGTTGGGGATCCCAACAAGTTTCGATTCAGACTACGATTCTGCAAGTGTTG
ATGGTTTCTCAGGTGGTAACAGAGAGCTTAAAGCAGAAGAATCTACAAGTTATACTGTTGGTGGTGTTTTCCAACCAAGC
TTTGTTGATGGCTTAGTGCTAACTGTTGATTATTGGAATATCAAAATTGACGATGCTATCAGCGCGGTTTCTGCCCAAGA
TATTATTGACAAATGTGTTGATTCTCCAAGTGGCGTTAACAACGAATATTGTGCGTTGATTACACGTGATCCAAACAGTC
ACGAAATTACATCAATTCGTCAATATGCGTTGAATATCTCTTCATTAGAAGCTGCTGGTATCGATTTCGATATCGGTTAC
AACTTTGAACTCTTTGGTGGTGATTTACGTTCAAACTTGATTGCGACCAAGTTACTCAAGAGAAGAGATTACTCATTCCA
AGATGAACCAGATGTCTATGAAAACTATGTAGGTGTAGTTGGTACTCCTGAATGGCAGGCTAACTTAACCTTTAACTATT
CATGGAATAGCTGGCAGGCTACTTGGAGAACTCGCTTCATTGAGGGGGTAAGCTTATACACAGATCAAGAGCTTGCAGTA
AATGCTAACCCAAATAGCCTATTATCTTATGGTGACTATTACATTAGCGATATGGGTATTGGGTACAACTTCGATAATGG
TATAGAGCTGAAGGTTGGTGTCGATAACCTGTTCAATAAAGACTTACCTTACGGGTCTACTGGTACAACAGCTGGTTCTG
CGGCTTATGACAACATAGGACGTTTCTTCTATACAACCATTAGCTTTAGTCTGTAA

Upstream 100 bases:

>100_bases
AATAACCCAATTTGTTGACTAGTTGTTTTTCAGGTGATAAAAGTTTGTCTCCAAAGTTGTTTGTTTGTTTAATATAAAAA
TAAATATAGGGAGAGATAGA

Downstream 100 bases:

>100_bases
TGGTCTATAATTGACTTTTAGATTAATTACATAATTTTTTGAACTAAATTCAACATCAAAAAAGGGCTCAAATTAATTTG
AGCCCTTTTTCTTTTATGTC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 951; Mature: 950

Protein sequence:

>951_residues
MAIESYLTKAVRVALVASTASIMFGASAYAAEDAPGANKKEEVERIAVTGSRIIREGAIAPTPVTVITGEELLSTGVTNI
GEALNQLPALGSTYSLANSGRFIGTSGLNLLDLRNMGTDRTLVLVDGRRHVASSSGTSSVDINTIPSTWVEKVEVITGGA
SAIYGADAVTGVVNFILKKHVTGLDVSTTLGTAEDSNFTKKRFSVSYGTDFDNGRGNIAGAFEYSGQNQLKAFDRDQTAT
SFASITNSNRPNGDENDPAYPDKILTPNAGHYRISNAGTFNLNGWKTFNPDGSIKDVYIGPNSDGGYCADCDYTNLNQFV
ELQPEFDRYNFNVKGNYAISDDMNFYAEGKYVRSKSHDMFQPAFFFFNPVNTISIDNAFIQDDLRDLMTANGKTSLTINR
FTTDLGLRLEDDTRETQRYVVGLEGNLLEDWSYDVFATYGQTDLERVNRNNLVYANYENALDSILVDGVAVCRDEAARAA
GCVPVNIFGDGQASQGARDYINTTSTGSSVIKQTVLGGSVTNSALFDLPAGAVGFSAGVEYRKEESEVFEPDNAEGTFFN
VLGEDKGDFDVKEVFAEISVPLLSDLPLVRQLDAELAARYANYSTIGSATTWKAGLSWEVYDDLRIRSTYSEAIRAPNIS
ELFGAQSQNFFNVDDSCKSSELDNLANSELRRQNCAALGIPTSFDSDYDSASVDGFSGGNRELKAEESTSYTVGGVFQPS
FVDGLVLTVDYWNIKIDDAISAVSAQDIIDKCVDSPSGVNNEYCALITRDPNSHEITSIRQYALNISSLEAAGIDFDIGY
NFELFGGDLRSNLIATKLLKRRDYSFQDEPDVYENYVGVVGTPEWQANLTFNYSWNSWQATWRTRFIEGVSLYTDQELAV
NANPNSLLSYGDYYISDMGIGYNFDNGIELKVGVDNLFNKDLPYGSTGTTAGSAAYDNIGRFFYTTISFSL

Sequences:

>Translated_951_residues
MAIESYLTKAVRVALVASTASIMFGASAYAAEDAPGANKKEEVERIAVTGSRIIREGAIAPTPVTVITGEELLSTGVTNI
GEALNQLPALGSTYSLANSGRFIGTSGLNLLDLRNMGTDRTLVLVDGRRHVASSSGTSSVDINTIPSTWVEKVEVITGGA
SAIYGADAVTGVVNFILKKHVTGLDVSTTLGTAEDSNFTKKRFSVSYGTDFDNGRGNIAGAFEYSGQNQLKAFDRDQTAT
SFASITNSNRPNGDENDPAYPDKILTPNAGHYRISNAGTFNLNGWKTFNPDGSIKDVYIGPNSDGGYCADCDYTNLNQFV
ELQPEFDRYNFNVKGNYAISDDMNFYAEGKYVRSKSHDMFQPAFFFFNPVNTISIDNAFIQDDLRDLMTANGKTSLTINR
FTTDLGLRLEDDTRETQRYVVGLEGNLLEDWSYDVFATYGQTDLERVNRNNLVYANYENALDSILVDGVAVCRDEAARAA
GCVPVNIFGDGQASQGARDYINTTSTGSSVIKQTVLGGSVTNSALFDLPAGAVGFSAGVEYRKEESEVFEPDNAEGTFFN
VLGEDKGDFDVKEVFAEISVPLLSDLPLVRQLDAELAARYANYSTIGSATTWKAGLSWEVYDDLRIRSTYSEAIRAPNIS
ELFGAQSQNFFNVDDSCKSSELDNLANSELRRQNCAALGIPTSFDSDYDSASVDGFSGGNRELKAEESTSYTVGGVFQPS
FVDGLVLTVDYWNIKIDDAISAVSAQDIIDKCVDSPSGVNNEYCALITRDPNSHEITSIRQYALNISSLEAAGIDFDIGY
NFELFGGDLRSNLIATKLLKRRDYSFQDEPDVYENYVGVVGTPEWQANLTFNYSWNSWQATWRTRFIEGVSLYTDQELAV
NANPNSLLSYGDYYISDMGIGYNFDNGIELKVGVDNLFNKDLPYGSTGTTAGSAAYDNIGRFFYTTISFSL
>Mature_950_residues
AIESYLTKAVRVALVASTASIMFGASAYAAEDAPGANKKEEVERIAVTGSRIIREGAIAPTPVTVITGEELLSTGVTNIG
EALNQLPALGSTYSLANSGRFIGTSGLNLLDLRNMGTDRTLVLVDGRRHVASSSGTSSVDINTIPSTWVEKVEVITGGAS
AIYGADAVTGVVNFILKKHVTGLDVSTTLGTAEDSNFTKKRFSVSYGTDFDNGRGNIAGAFEYSGQNQLKAFDRDQTATS
FASITNSNRPNGDENDPAYPDKILTPNAGHYRISNAGTFNLNGWKTFNPDGSIKDVYIGPNSDGGYCADCDYTNLNQFVE
LQPEFDRYNFNVKGNYAISDDMNFYAEGKYVRSKSHDMFQPAFFFFNPVNTISIDNAFIQDDLRDLMTANGKTSLTINRF
TTDLGLRLEDDTRETQRYVVGLEGNLLEDWSYDVFATYGQTDLERVNRNNLVYANYENALDSILVDGVAVCRDEAARAAG
CVPVNIFGDGQASQGARDYINTTSTGSSVIKQTVLGGSVTNSALFDLPAGAVGFSAGVEYRKEESEVFEPDNAEGTFFNV
LGEDKGDFDVKEVFAEISVPLLSDLPLVRQLDAELAARYANYSTIGSATTWKAGLSWEVYDDLRIRSTYSEAIRAPNISE
LFGAQSQNFFNVDDSCKSSELDNLANSELRRQNCAALGIPTSFDSDYDSASVDGFSGGNRELKAEESTSYTVGGVFQPSF
VDGLVLTVDYWNIKIDDAISAVSAQDIIDKCVDSPSGVNNEYCALITRDPNSHEITSIRQYALNISSLEAAGIDFDIGYN
FELFGGDLRSNLIATKLLKRRDYSFQDEPDVYENYVGVVGTPEWQANLTFNYSWNSWQATWRTRFIEGVSLYTDQELAVN
ANPNSLLSYGDYYISDMGIGYNFDNGIELKVGVDNLFNKDLPYGSTGTTAGSAAYDNIGRFFYTTISFSL

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=176, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790405, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 103717; Mature: 103586

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIESYLTKAVRVALVASTASIMFGASAYAAEDAPGANKKEEVERIAVTGSRIIREGAIA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PTPVTVITGEELLSTGVTNIGEALNQLPALGSTYSLANSGRFIGTSGLNLLDLRNMGTDR
CCCEEEEECHHHHHHCHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCEEEECCCCCCC
TLVLVDGRRHVASSSGTSSVDINTIPSTWVEKVEVITGGASAIYGADAVTGVVNFILKKH
EEEEECCCHHCCCCCCCCEEEECCCCHHHHHEEEEEECCCHHCCCHHHHHHHHHHHHHHC
VTGLDVSTTLGTAEDSNFTKKRFSVSYGTDFDNGRGNIAGAFEYSGQNQLKAFDRDQTAT
CCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCHHECCCCCHHHH
SFASITNSNRPNGDENDPAYPDKILTPNAGHYRISNAGTFNLNGWKTFNPDGSIKDVYIG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCEEECCCCCEEEEEEC
PNSDGGYCADCDYTNLNQFVELQPEFDRYNFNVKGNYAISDDMNFYAEGKYVRSKSHDMF
CCCCCCEEECCCCCCCCCEEEECCCCCCEEEEEECCEEECCCCCEEECCEEEECCCCCCC
QPAFFFFNPVNTISIDNAFIQDDLRDLMTANGKTSLTINRFTTDLGLRLEDDTRETQRYV
CCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEECCCCCCCEEEE
VGLEGNLLEDWSYDVFATYGQTDLERVNRNNLVYANYENALDSILVDGVAVCRDEAARAA
EECCCCEECCCCCCEEEECCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GCVPVNIFGDGQASQGARDYINTTSTGSSVIKQTVLGGSVTNSALFDLPAGAVGFSAGVE
CCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHCCCC
YRKEESEVFEPDNAEGTFFNVLGEDKGDFDVKEVFAEISVPLLSDLPLVRQLDAELAARY
CCCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
ANYSTIGSATTWKAGLSWEVYDDLRIRSTYSEAIRAPNISELFGAQSQNFFNVDDSCKSS
CCCCCCCCCCEECCCCCEEEECCEEEHHHHHHHHCCCCHHHHHCCCCCCEECCCCCCCHH
ELDNLANSELRRQNCAALGIPTSFDSDYDSASVDGFSGGNRELKAEESTSYTVGGVFQPS
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCEECCH
FVDGLVLTVDYWNIKIDDAISAVSAQDIIDKCVDSPSGVNNEYCALITRDPNSHEITSIR
HHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHH
QYALNISSLEAAGIDFDIGYNFELFGGDLRSNLIATKLLKRRDYSFQDEPDVYENYVGVV
HHHHCHHHHEECCCEEECCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCE
GTPEWQANLTFNYSWNSWQATWRTRFIEGVSLYTDQELAVNANPNSLLSYGDYYISDMGI
ECCCEEEEEEEEECCCCCHHHHHHHHHCCEEEEECCEEEEECCCCHHHHCCCEEEEECCC
GYNFDNGIELKVGVDNLFNKDLPYGSTGTTAGSAAYDNIGRFFYTTISFSL
CCCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEECC
>Mature Secondary Structure 
AIESYLTKAVRVALVASTASIMFGASAYAAEDAPGANKKEEVERIAVTGSRIIREGAIA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PTPVTVITGEELLSTGVTNIGEALNQLPALGSTYSLANSGRFIGTSGLNLLDLRNMGTDR
CCCEEEEECHHHHHHCHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCEEEECCCCCCC
TLVLVDGRRHVASSSGTSSVDINTIPSTWVEKVEVITGGASAIYGADAVTGVVNFILKKH
EEEEECCCHHCCCCCCCCEEEECCCCHHHHHEEEEEECCCHHCCCHHHHHHHHHHHHHHC
VTGLDVSTTLGTAEDSNFTKKRFSVSYGTDFDNGRGNIAGAFEYSGQNQLKAFDRDQTAT
CCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCHHECCCCCHHHH
SFASITNSNRPNGDENDPAYPDKILTPNAGHYRISNAGTFNLNGWKTFNPDGSIKDVYIG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCEEECCCCCEEEEEEC
PNSDGGYCADCDYTNLNQFVELQPEFDRYNFNVKGNYAISDDMNFYAEGKYVRSKSHDMF
CCCCCCEEECCCCCCCCCEEEECCCCCCEEEEEECCEEECCCCCEEECCEEEECCCCCCC
QPAFFFFNPVNTISIDNAFIQDDLRDLMTANGKTSLTINRFTTDLGLRLEDDTRETQRYV
CCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEECCCCCCCEEEE
VGLEGNLLEDWSYDVFATYGQTDLERVNRNNLVYANYENALDSILVDGVAVCRDEAARAA
EECCCCEECCCCCCEEEECCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GCVPVNIFGDGQASQGARDYINTTSTGSSVIKQTVLGGSVTNSALFDLPAGAVGFSAGVE
CCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHCCCC
YRKEESEVFEPDNAEGTFFNVLGEDKGDFDVKEVFAEISVPLLSDLPLVRQLDAELAARY
CCCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
ANYSTIGSATTWKAGLSWEVYDDLRIRSTYSEAIRAPNISELFGAQSQNFFNVDDSCKSS
CCCCCCCCCCEECCCCCEEEECCEEEHHHHHHHHCCCCHHHHHCCCCCCEECCCCCCCHH
ELDNLANSELRRQNCAALGIPTSFDSDYDSASVDGFSGGNRELKAEESTSYTVGGVFQPS
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCEECCH
FVDGLVLTVDYWNIKIDDAISAVSAQDIIDKCVDSPSGVNNEYCALITRDPNSHEITSIR
HHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHH
QYALNISSLEAAGIDFDIGYNFELFGGDLRSNLIATKLLKRRDYSFQDEPDVYENYVGVV
HHHHCHHHHEECCCEEECCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCE
GTPEWQANLTFNYSWNSWQATWRTRFIEGVSLYTDQELAVNANPNSLLSYGDYYISDMGI
ECCCEEEEEEEEECCCCCHHHHHHHHHCCEEEEECCEEEEECCCCHHHHCCCEEEEECCC
GYNFDNGIELKVGVDNLFNKDLPYGSTGTTAGSAAYDNIGRFFYTTISFSL
CCCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA