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The map label for this gene is fabZ

Identifier: 108762744

GI number: 108762744

Start: 5919203

End: 5919664

Strand: Reverse

Name: fabZ

Synonym: MXAN_4725

Alternate gene names: 108762744

Gene position: 5919664-5919203 (Counterclockwise)

Preceding gene: 108758832

Following gene: 108760565

Centisome position: 64.77

GC content: 65.15

Gene sequence:

>462_bases
ATGGACATCGGAGAGATTCTCAATCTGCTGCCGCATCGGTACCCGTTCCTGCTGGTGGACCGGGTGGTGGAGATCATCCC
GGGCCAGAAGCTGACGGCCTACAAGAACGTCACCATCAACGAGCCCTTCTTCAACGGGCACTTCCCCGGTCACCCGGTGA
TGCCGGGTGTGCTCATCCTGGAGGCGCTGGCGCAGGCGACGGCCATCCTCGCCTACAAGAGCGAGAACATGGATCCGTCG
CGCAAGCTCACGTACCTGATGGGCGTGGACGGCGCGCGCTTCCGCAAGCCGGTGTTGCCGGGGGATCGCCTCCAGTTGGA
GATCGAGGTGGTGCGTCACAAGGGCGCTGTCTGGAAGACGAAGGGCCTGGCGACGGTCGACGGCGCGCGTGTCGCCGAAG
GCGAGTTCCTGGCAACCGTCGTGGACAAGGACGCCGACGCGGCTGAGAGCGCGGCATCCTGA

Upstream 100 bases:

>100_bases
TGCGGGCCAGCGCCGCGGCGGGCCAGATGGCGGACCTGCTCAAGGAAGTGCGCGCCCTGCGGCGCCGGGTGGAGACGCTG
GAGAAGGAAAAGGGGCCGTG

Downstream 100 bases:

>100_bases
TTCGCGCCCCGCGAGCACGAGGAGACTTCATGGCTCAGGTTCATCCCACCGCGGTGGTTCATCCCGACGCCCGCCTTCAC
GAAACCGTCGAGGTCGGCCC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MDIGEILNLLPHRYPFLLVDRVVEIIPGQKLTAYKNVTINEPFFNGHFPGHPVMPGVLILEALAQATAILAYKSENMDPS
RKLTYLMGVDGARFRKPVLPGDRLQLEIEVVRHKGAVWKTKGLATVDGARVAEGEFLATVVDKDADAAESAAS

Sequences:

>Translated_153_residues
MDIGEILNLLPHRYPFLLVDRVVEIIPGQKLTAYKNVTINEPFFNGHFPGHPVMPGVLILEALAQATAILAYKSENMDPS
RKLTYLMGVDGARFRKPVLPGDRLQLEIEVVRHKGAVWKTKGLATVDGARVAEGEFLATVVDKDADAAESAAS
>Mature_153_residues
MDIGEILNLLPHRYPFLLVDRVVEIIPGQKLTAYKNVTINEPFFNGHFPGHPVMPGVLILEALAQATAILAYKSENMDPS
RKLTYLMGVDGARFRKPVLPGDRLQLEIEVVRHKGAVWKTKGLATVDGARVAEGEFLATVVDKDADAAESAAS

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=52.1739130434783, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_MYXXD (Q1D386)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_632887.1
- ProteinModelPortal:   Q1D386
- SMR:   Q1D386
- STRING:   Q1D386
- GeneID:   4106497
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4725
- TIGR:   MXAN_4725
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   NVSANES
- PhylomeDB:   Q1D386
- BioCyc:   MXAN246197:MXAN_4725-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16735; Mature: 16735

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGEILNLLPHRYPFLLVDRVVEIIPGQKLTAYKNVTINEPFFNGHFPGHPVMPGVLIL
CCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCEECCCCCCCCCCCCCCCHHHHHH
EALAQATAILAYKSENMDPSRKLTYLMGVDGARFRKPVLPGDRLQLEIEVVRHKGAVWKT
HHHHHHHHHEEECCCCCCCCCEEEEEECCCCHHHCCCCCCCCCEEEEEEEEECCCCEEEC
KGLATVDGARVAEGEFLATVVDKDADAAESAAS
CCCEEECCCEECCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDIGEILNLLPHRYPFLLVDRVVEIIPGQKLTAYKNVTINEPFFNGHFPGHPVMPGVLIL
CCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCEECCCCCCCCCCCCCCCHHHHHH
EALAQATAILAYKSENMDPSRKLTYLMGVDGARFRKPVLPGDRLQLEIEVVRHKGAVWKT
HHHHHHHHHEEECCCCCCCCCEEEEEECCCCHHHCCCCCCCCCEEEEEEEEECCCCEEEC
KGLATVDGARVAEGEFLATVVDKDADAAESAAS
CCCEEECCCEECCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA