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The map label for this gene is kynB

Identifier: 103486876

GI number: 103486876

Start: 1445842

End: 1446471

Strand: Reverse

Name: kynB

Synonym: Sala_1390

Alternate gene names: 103486876

Gene position: 1446471-1445842 (Counterclockwise)

Preceding gene: 103486877

Following gene: 103486875

Centisome position: 43.24

GC content: 66.35

Gene sequence:

>630_bases
ATGAGCCGGATTTGGGACATTTCCCAGCCGCTGCACGCCGCGGTGCCGGTGTGGCCCGGCGAGCCCGCCTTCTCGCTCCA
CAGCCATGCGGTGATCGGCGAGGGCTGTCCGGTCAATGTCGGCGGCATGTTCACGCCGCTGCACGCGGGGACGCACGGCG
ATGCGCCGCTCCATTACAGCAATGACGGCGCCTCGTCGGCCGACTGCGAACTCGCTCCCTATATCGGACCGTGCGCGCTC
ATCGACGTGCGCCATGCGCGCGGGCGGGTGGAGATTGGCGACATCGACTGGAGCTGCGTCGACGGCGCAGAGCGTGTCCT
GCTGCGAACCTATGAACAATTTCCGCACGAAAAATGGGACAGCGATTTCACCGCCGTCGCTGCGGACGTGATCGAACGGT
TTGGTGCGATGGGCGTCCGCCTGATCGGCACCGACGCCGCCTCGCTCGATCCCGAACAGTCGAAAACGCTCGACGCGCAT
CAGGCGGTGAAGGCTGCCGACATGCGGATCCTGGAGGGGCTGGTGCTCGATGATGTGCCGCCCGGCCGCTACGAACTGAT
TGCCCTGCCGCTGCGCATCGTCGGCGCCGATGCCAGCCCGGTGCGCGCCATTCTGAGGGAAATCGCATGA

Upstream 100 bases:

>100_bases
TCAAGGCGCTCGATCTCAGCTTCTTTCCCGAACTCTGGTCGATGCGGACCGAAATGGTCGCGCCGCGCGAGGGTGGCGAC
TATGCGGCAGGGGAACGCAA

Downstream 100 bases:

>100_bases
CCGGCACGATGGCCGTCGCCGATGTGGTGTCGCTCGACGCGGGCGACCCGCTCGCGCCTTTTCGCGACCGCTTTCATCTG
CGCGAAGGGCTGATCTATCT

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSRIWDISQPLHAAVPVWPGEPAFSLHSHAVIGEGCPVNVGGMFTPLHAGTHGDAPLHYSNDGASSADCELAPYIGPCAL
IDVRHARGRVEIGDIDWSCVDGAERVLLRTYEQFPHEKWDSDFTAVAADVIERFGAMGVRLIGTDAASLDPEQSKTLDAH
QAVKAADMRILEGLVLDDVPPGRYELIALPLRIVGADASPVRAILREIA

Sequences:

>Translated_209_residues
MSRIWDISQPLHAAVPVWPGEPAFSLHSHAVIGEGCPVNVGGMFTPLHAGTHGDAPLHYSNDGASSADCELAPYIGPCAL
IDVRHARGRVEIGDIDWSCVDGAERVLLRTYEQFPHEKWDSDFTAVAADVIERFGAMGVRLIGTDAASLDPEQSKTLDAH
QAVKAADMRILEGLVLDDVPPGRYELIALPLRIVGADASPVRAILREIA
>Mature_208_residues
SRIWDISQPLHAAVPVWPGEPAFSLHSHAVIGEGCPVNVGGMFTPLHAGTHGDAPLHYSNDGASSADCELAPYIGPCALI
DVRHARGRVEIGDIDWSCVDGAERVLLRTYEQFPHEKWDSDFTAVAADVIERFGAMGVRLIGTDAASLDPEQSKTLDAHQ
AVKAADMRILEGLVLDDVPPGRYELIALPLRIVGADASPVRAILREIA

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_SPHAL (Q1GTB8)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616437.1
- ProteinModelPortal:   Q1GTB8
- SMR:   Q1GTB8
- GeneID:   4081862
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1390
- NMPDR:   fig|317655.9.peg.1324
- HOGENOM:   HBG686791
- OMA:   CPVNVGR
- BioCyc:   SALA317655:SALA_1390-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 22461; Mature: 22329

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIWDISQPLHAAVPVWPGEPAFSLHSHAVIGEGCPVNVGGMFTPLHAGTHGDAPLHYS
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEC
NDGASSADCELAPYIGPCALIDVRHARGRVEIGDIDWSCVDGAERVLLRTYEQFPHEKWD
CCCCCCCCCEECCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCC
SDFTAVAADVIERFGAMGVRLIGTDAASLDPEQSKTLDAHQAVKAADMRILEGLVLDDVP
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PGRYELIALPLRIVGADASPVRAILREIA
CCCEEEEEEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
SRIWDISQPLHAAVPVWPGEPAFSLHSHAVIGEGCPVNVGGMFTPLHAGTHGDAPLHYS
CCCCCCCCCHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEC
NDGASSADCELAPYIGPCALIDVRHARGRVEIGDIDWSCVDGAERVLLRTYEQFPHEKWD
CCCCCCCCCEECCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCC
SDFTAVAADVIERFGAMGVRLIGTDAASLDPEQSKTLDAHQAVKAADMRILEGLVLDDVP
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PGRYELIALPLRIVGADASPVRAILREIA
CCCEEEEEEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA