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The map label for this gene is grxC [H]

Identifier: 103485623

GI number: 103485623

Start: 122968

End: 123243

Strand: Direct

Name: grxC [H]

Synonym: Sala_0127

Alternate gene names: 103485623

Gene position: 122968-123243 (Clockwise)

Preceding gene: 103485622

Following gene: 103485629

Centisome position: 3.68

GC content: 57.97

Gene sequence:

>276_bases
ATGAAACCGAACATAACCCTCTATACCAAGGACTATTGCCCCTTTTGTCACCGGGCCAAGGCGCATCTTCGCGCCAAGGG
GGTGACCGACTGGATCGAAATCGACGTCGAAGATGATCCGGTGCAGTTCCGTGCAATGCAGACAGCGTCTGGTGGACGCA
GGACGGTTCCGCAGATCTTCATCAACGGTACGCATGTGGGCGGGTCGGATGATCTGGTGGCGCTCGATGCCGACGGCGGC
CTCGATTTGCTGCTGCGCGAAAAGATGCTCGTCTGA

Upstream 100 bases:

>100_bases
GAGCGCCGTCCCAATGGTTACACCTGCCACTTTCCGCGCGCCGCCTGGGTCCTTCCATCGGCCGGCGAGCGGTCTGAGGC
AGCTTGATCGGAGACATGAA

Downstream 100 bases:

>100_bases
AACTAACGGGCGTCCGCCGAACAGCGGGCGCCCGTTTGCGCGTTACCGTGAGCCGCCCCGGAGTTGCTCGCGCTTAGAGC
CAACGGCGATCGGCCGTGAA

Product: glutaredoxin GrxC

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MKPNITLYTKDYCPFCHRAKAHLRAKGVTDWIEIDVEDDPVQFRAMQTASGGRRTVPQIFINGTHVGGSDDLVALDADGG
LDLLLREKMLV

Sequences:

>Translated_91_residues
MKPNITLYTKDYCPFCHRAKAHLRAKGVTDWIEIDVEDDPVQFRAMQTASGGRRTVPQIFINGTHVGGSDDLVALDADGG
LDLLLREKMLV
>Mature_91_residues
MKPNITLYTKDYCPFCHRAKAHLRAKGVTDWIEIDVEDDPVQFRAMQTASGGRRTVPQIFINGTHVGGSDDLVALDADGG
LDLLLREKMLV

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=53.0120481927711, Blast_Score=88, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509845, Length=87, Percent_Identity=39.0804597701149, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10114; Mature: 10114

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNITLYTKDYCPFCHRAKAHLRAKGVTDWIEIDVEDDPVQFRAMQTASGGRRTVPQIF
CCCCEEEEECCCCCCHHHCCHHEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCEEE
INGTHVGGSDDLVALDADGGLDLLLREKMLV
EECEEECCCCCEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MKPNITLYTKDYCPFCHRAKAHLRAKGVTDWIEIDVEDDPVQFRAMQTASGGRRTVPQIF
CCCCEEEEECCCCCCHHHCCHHEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCEEE
INGTHVGGSDDLVALDADGGLDLLLREKMLV
EECEEECCCCCEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]