| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
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The map label for this gene is yeaE [H]
Identifier: 239618124
GI number: 239618124
Start: 1888073
End: 1888885
Strand: Reverse
Name: yeaE [H]
Synonym: Kole_1757
Alternate gene names: 239618124
Gene position: 1888885-1888073 (Counterclockwise)
Preceding gene: 239618129
Following gene: 239618123
Centisome position: 82.05
GC content: 40.59
Gene sequence:
>813_bases ATGGGTTTCAAACAATTGGGAAGTACGGGTGAAGAGATTCCCGCTATAGGATTGGGAACATGGGAAATAGGCGGCAGGGA AACCCCAGATTATTCGCGGGACAAAGAAAACATTAAAATTCTTCAGGCTGCGATTGAGATGGGATATACACACATCGACA CGGCAGAGTATTATGGTGGTGGGCACACCGAAGAACTCATAGGAGAAGCAATAAAAACCTTTGACAGGAGTAAACTTTTC ATAACATCAAAAGTCTGGCCAACTCACCTCTCAAAAGAAGAGCTTCCGAAAGCCCTTAAAGGATCTCTAAAAAGATTGGG GACAGATTACATCGATTTATATCTGATCCACTGGCCAGTTCCTGATATGGACCTAAAAGAAACCCTGACCACAATGGCAG AACTGTCAAAAGCCGGATATATAAGATACATAGGAGTTTCAAATTTTGACGTGGCACTATTAAAGAAATCGCTGCTCATT TCTCCTGTCCCGATTGTCTGTAACCAGGTTCTTTATAACCTTGAAGACCGAGAACCAGAAAACGAGCTTTTACCCTTCTG TCAGGAAAACGGTATTACCCTTACAGCATATACACCACTTAAAAAAGGAAGCCTTTCAAAACATACAGAAAAAGTGCTTA AAAAAATCGCTAAAAAACATAACGCTACAATCTACCAGATTATGCTTTCATGGCTAATTTCAAAAGACAACGTCATTGCA ATCCCCCGCTCCACAAATATTCAACATCTAAAAGAAAATCTCGAAGCCGCTGACATTATCCTTGAACCTGATGATCTCCA ATTACTGGATTAA
Upstream 100 bases:
>100_bases ATCATGTTCCGCACTTATCATATCACAACCACAGTGTTGTCTAATGCGTTTTTACTGCAATGGCAATTTGATAAAATAAC CCATGAAAGGTGGTGCTTTC
Downstream 100 bases:
>100_bases TTTTCCTAAATTGGTTATGCGTTGAAAAGCCCTGACCGAGAAAAAGGATTCTTTTATTGGGAATGTAAACTCCGAGTAAT ATAATCGGAATTAGTCTTTG
Product: aldo/keto reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 270; Mature: 269
Protein sequence:
>270_residues MGFKQLGSTGEEIPAIGLGTWEIGGRETPDYSRDKENIKILQAAIEMGYTHIDTAEYYGGGHTEELIGEAIKTFDRSKLF ITSKVWPTHLSKEELPKALKGSLKRLGTDYIDLYLIHWPVPDMDLKETLTTMAELSKAGYIRYIGVSNFDVALLKKSLLI SPVPIVCNQVLYNLEDREPENELLPFCQENGITLTAYTPLKKGSLSKHTEKVLKKIAKKHNATIYQIMLSWLISKDNVIA IPRSTNIQHLKENLEAADIILEPDDLQLLD
Sequences:
>Translated_270_residues MGFKQLGSTGEEIPAIGLGTWEIGGRETPDYSRDKENIKILQAAIEMGYTHIDTAEYYGGGHTEELIGEAIKTFDRSKLF ITSKVWPTHLSKEELPKALKGSLKRLGTDYIDLYLIHWPVPDMDLKETLTTMAELSKAGYIRYIGVSNFDVALLKKSLLI SPVPIVCNQVLYNLEDREPENELLPFCQENGITLTAYTPLKKGSLSKHTEKVLKKIAKKHNATIYQIMLSWLISKDNVIA IPRSTNIQHLKENLEAADIILEPDDLQLLD >Mature_269_residues GFKQLGSTGEEIPAIGLGTWEIGGRETPDYSRDKENIKILQAAIEMGYTHIDTAEYYGGGHTEELIGEAIKTFDRSKLFI TSKVWPTHLSKEELPKALKGSLKRLGTDYIDLYLIHWPVPDMDLKETLTTMAELSKAGYIRYIGVSNFDVALLKKSLLIS PVPIVCNQVLYNLEDREPENELLPFCQENGITLTAYTPLKKGSLSKHTEKVLKKIAKKHNATIYQIMLSWLISKDNVIAI PRSTNIQHLKENLEAADIILEPDDLQLLD
Specific function: Unknown
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Homo sapiens, GI223468663, Length=295, Percent_Identity=33.2203389830508, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI24497577, Length=296, Percent_Identity=29.3918918918919, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI5174391, Length=296, Percent_Identity=29.3918918918919, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI24497585, Length=303, Percent_Identity=30.03300330033, Blast_Score=118, Evalue=5e-27, Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=29.8360655737705, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI310109922, Length=286, Percent_Identity=32.5174825174825, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI291291012, Length=268, Percent_Identity=32.8358208955224, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI45446745, Length=305, Percent_Identity=31.4754098360656, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI4503285, Length=305, Percent_Identity=31.4754098360656, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI310109920, Length=305, Percent_Identity=31.4754098360656, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI24497583, Length=300, Percent_Identity=30.3333333333333, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI5453543, Length=305, Percent_Identity=30.8196721311475, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI5174695, Length=299, Percent_Identity=29.7658862876254, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI300116273, Length=289, Percent_Identity=30.4498269896194, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI4502049, Length=309, Percent_Identity=30.7443365695793, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=25, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=25, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=24.5954692556634, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=24.4299674267101, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=25, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI27436971, Length=320, Percent_Identity=24.0625, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI223718702, Length=206, Percent_Identity=30.5825242718447, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI207028673, Length=117, Percent_Identity=40.1709401709402, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI41152114, Length=206, Percent_Identity=31.0679611650485, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI310109926, Length=117, Percent_Identity=40.1709401709402, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1788081, Length=263, Percent_Identity=38.7832699619772, Blast_Score=183, Evalue=9e-48, Organism=Escherichia coli, GI1786400, Length=260, Percent_Identity=35.7692307692308, Blast_Score=145, Evalue=3e-36, Organism=Escherichia coli, GI87082198, Length=260, Percent_Identity=34.2307692307692, Blast_Score=137, Evalue=9e-34, Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=30.5732484076433, Blast_Score=134, Evalue=5e-33, Organism=Escherichia coli, GI87081735, Length=312, Percent_Identity=27.5641025641026, Blast_Score=124, Evalue=9e-30, Organism=Escherichia coli, GI1787674, Length=273, Percent_Identity=28.2051282051282, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1789375, Length=306, Percent_Identity=26.4705882352941, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789199, Length=336, Percent_Identity=28.2738095238095, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI48994888, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17561298, Length=288, Percent_Identity=30.9027777777778, Blast_Score=132, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=32.3232323232323, Blast_Score=128, Evalue=4e-30, Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=32.3232323232323, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI71998625, Length=272, Percent_Identity=34.5588235294118, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI17566692, Length=296, Percent_Identity=29.0540540540541, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17550248, Length=295, Percent_Identity=29.8305084745763, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17564128, Length=304, Percent_Identity=28.6184210526316, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17561300, Length=278, Percent_Identity=32.3741007194245, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI17552492, Length=276, Percent_Identity=28.2608695652174, Blast_Score=111, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17537079, Length=287, Percent_Identity=26.8292682926829, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17538386, Length=283, Percent_Identity=26.8551236749117, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562292, Length=282, Percent_Identity=30.8510638297872, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI212645785, Length=168, Percent_Identity=27.9761904761905, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6320576, Length=295, Percent_Identity=34.9152542372881, Blast_Score=140, Evalue=2e-34, Organism=Saccharomyces cerevisiae, GI6324694, Length=280, Percent_Identity=33.5714285714286, Blast_Score=138, Evalue=1e-33, Organism=Saccharomyces cerevisiae, GI6319625, Length=300, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=4e-28, Organism=Saccharomyces cerevisiae, GI6320079, Length=290, Percent_Identity=32.0689655172414, Blast_Score=103, Evalue=3e-23, Organism=Saccharomyces cerevisiae, GI6322556, Length=277, Percent_Identity=28.5198555956679, Blast_Score=95, Evalue=9e-21, Organism=Saccharomyces cerevisiae, GI6321896, Length=299, Percent_Identity=25.752508361204, Blast_Score=88, Evalue=1e-18, Organism=Saccharomyces cerevisiae, GI6325169, Length=236, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=4e-18, Organism=Saccharomyces cerevisiae, GI6319958, Length=290, Percent_Identity=24.4827586206897, Blast_Score=76, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6323998, Length=290, Percent_Identity=24.1379310344828, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6319951, Length=283, Percent_Identity=22.6148409893993, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24663317, Length=295, Percent_Identity=31.864406779661, Blast_Score=133, Evalue=1e-31, Organism=Drosophila melanogaster, GI24657054, Length=293, Percent_Identity=29.6928327645051, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24644950, Length=307, Percent_Identity=32.8990228013029, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI24662789, Length=301, Percent_Identity=29.9003322259136, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI221378297, Length=326, Percent_Identity=30.6748466257669, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI20129731, Length=285, Percent_Identity=29.4736842105263, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI21356425, Length=296, Percent_Identity=28.0405405405405, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI45553081, Length=295, Percent_Identity=30.8474576271186, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI281366140, Length=255, Percent_Identity=31.7647058823529, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI24646159, Length=288, Percent_Identity=30.2083333333333, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24662781, Length=291, Percent_Identity=29.2096219931272, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24662785, Length=289, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24646155, Length=171, Percent_Identity=35.0877192982456, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24640980, Length=212, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI45549126, Length=215, Percent_Identity=29.3023255813954, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 30397; Mature: 30266
Theoretical pI: Translated: 5.66; Mature: 5.66
Prosite motif: PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGFKQLGSTGEEIPAIGLGTWEIGGRETPDYSRDKENIKILQAAIEMGYTHIDTAEYYGG CCHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCC GHTEELIGEAIKTFDRSKLFITSKVWPTHLSKEELPKALKGSLKRLGTDYIDLYLIHWPV CCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC PDMDLKETLTTMAELSKAGYIRYIGVSNFDVALLKKSLLISPVPIVCNQVLYNLEDREPE CCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCH NELLPFCQENGITLTAYTPLKKGSLSKHTEKVLKKIAKKHNATIYQIMLSWLISKDNVIA HHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEE IPRSTNIQHLKENLEAADIILEPDDLQLLD ECCCCCHHHHHHCCCHHHEEECCCCCEECC >Mature Secondary Structure GFKQLGSTGEEIPAIGLGTWEIGGRETPDYSRDKENIKILQAAIEMGYTHIDTAEYYGG CHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCC GHTEELIGEAIKTFDRSKLFITSKVWPTHLSKEELPKALKGSLKRLGTDYIDLYLIHWPV CCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC PDMDLKETLTTMAELSKAGYIRYIGVSNFDVALLKKSLLISPVPIVCNQVLYNLEDREPE CCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCH NELLPFCQENGITLTAYTPLKKGSLSKHTEKVLKKIAKKHNATIYQIMLSWLISKDNVIA HHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEE IPRSTNIQHLKENLEAADIILEPDDLQLLD ECCCCCHHHHHHCCCHHHEEECCCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9097040; 9278503 [H]