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The map label for this gene is pyrH [H]

Identifier: 239618074

GI number: 239618074

Start: 1836027

End: 1836728

Strand: Reverse

Name: pyrH [H]

Synonym: Kole_1706

Alternate gene names: 239618074

Gene position: 1836728-1836027 (Counterclockwise)

Preceding gene: 239618075

Following gene: 239618073

Centisome position: 79.78

GC content: 43.3

Gene sequence:

>702_bases
ATGTACAGGAGAGTATTGTTAAAACTCAGTGGTGAAGCCCTTAGTGGCGAGGGCAATAAAGGATTCAGCGAAGAAAGGTT
ACAATATCTCGTTAACGAACTTCGCGGCGTAAAGGAACGTGGAATCGAGATTGCAATCGTCATAGGTGCAGGCAACCTCT
TCCGAGGCAAAGAGCTAACACATATTTCTCCCACCGTATCCGACGAGATCGGGATGTTGGGAACCCTGATTAACACACTC
TATCTGAAGGATTATCTCTCTTCAAAGGGATTGAAAGCGGTGGCAATTTCATCGATTGTCTCGTTCCCATCTTTCGAGCC
TTACAAATACAGCAGAGCAGAACAACTTCTGAGGGAAGGAAACATCGTTATTCTCGGTGGAGGAACGACAATTCCCTACT
TCACCACCGATACCGCAGCCGCTATCAGAGCAATTGAACTTCATACTGACATCATAATAAAAGCCACCAAGGTTGACGGT
GTATACGAACTCGATCCAAAGAAACATCCTGACACGAAAAAAATCGACAGAATCACTTTCACCGAAGCAATTGAACGGGA
TTTAAAGATAATGGATATAGAAGCTTTTTCCATTTGCAAAAAACATAAAATACCTATCATCGTTATCGATTTCTTTACCA
GCGGAAATCTGCTGCGTGCTATAATTGGCGAGAAAGTTGGTACTCTGGTAATTCCCGACTGA

Upstream 100 bases:

>100_bases
ATAAAGGTTAGCAGATTTGTTAGATGGGAAGTTGGGGAAAGCGATTAATAATGAAAGATAAAGAGGTGGGCATTGCTCAC
CTCTTTTTTTGGAGGGTGCT

Downstream 100 bases:

>100_bases
ATACAGGAGGTGTTAATATGTACGCCCAGATAGTTGATGTAATCGCAAGAGAGGTTCTCGATTCACGCGGAACACCAACA
GTAGAAGTTGAAGTCTGGCT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MYRRVLLKLSGEALSGEGNKGFSEERLQYLVNELRGVKERGIEIAIVIGAGNLFRGKELTHISPTVSDEIGMLGTLINTL
YLKDYLSSKGLKAVAISSIVSFPSFEPYKYSRAEQLLREGNIVILGGGTTIPYFTTDTAAAIRAIELHTDIIIKATKVDG
VYELDPKKHPDTKKIDRITFTEAIERDLKIMDIEAFSICKKHKIPIIVIDFFTSGNLLRAIIGEKVGTLVIPD

Sequences:

>Translated_233_residues
MYRRVLLKLSGEALSGEGNKGFSEERLQYLVNELRGVKERGIEIAIVIGAGNLFRGKELTHISPTVSDEIGMLGTLINTL
YLKDYLSSKGLKAVAISSIVSFPSFEPYKYSRAEQLLREGNIVILGGGTTIPYFTTDTAAAIRAIELHTDIIIKATKVDG
VYELDPKKHPDTKKIDRITFTEAIERDLKIMDIEAFSICKKHKIPIIVIDFFTSGNLLRAIIGEKVGTLVIPD
>Mature_233_residues
MYRRVLLKLSGEALSGEGNKGFSEERLQYLVNELRGVKERGIEIAIVIGAGNLFRGKELTHISPTVSDEIGMLGTLINTL
YLKDYLSSKGLKAVAISSIVSFPSFEPYKYSRAEQLLREGNIVILGGGTTIPYFTTDTAAAIRAIELHTDIIIKATKVDG
VYELDPKKHPDTKKIDRITFTEAIERDLKIMDIEAFSICKKHKIPIIVIDFFTSGNLLRAIIGEKVGTLVIPD

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=41.8103448275862, Blast_Score=194, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25798; Mature: 25798

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRRVLLKLSGEALSGEGNKGFSEERLQYLVNELRGVKERGIEIAIVIGAGNLFRGKELT
CCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCE
HISPTVSDEIGMLGTLINTLYLKDYLSSKGLKAVAISSIVSFPSFEPYKYSRAEQLLREG
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
NIVILGGGTTIPYFTTDTAAAIRAIELHTDIIIKATKVDGVYELDPKKHPDTKKIDRITF
CEEEEECCCCCCEEECCHHHHHEEEEEECEEEEEEEECCCEEEECCCCCCCCHHHHHHHH
TEAIERDLKIMDIEAFSICKKHKIPIIVIDFFTSGNLLRAIIGEKVGTLVIPD
HHHHHCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MYRRVLLKLSGEALSGEGNKGFSEERLQYLVNELRGVKERGIEIAIVIGAGNLFRGKELT
CCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCE
HISPTVSDEIGMLGTLINTLYLKDYLSSKGLKAVAISSIVSFPSFEPYKYSRAEQLLREG
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
NIVILGGGTTIPYFTTDTAAAIRAIELHTDIIIKATKVDGVYELDPKKHPDTKKIDRITF
CEEEEECCCCCCEEECCHHHHHEEEEEECEEEEEEEECCCEEEECCCCCCCCHHHHHHHH
TEAIERDLKIMDIEAFSICKKHKIPIIVIDFFTSGNLLRAIIGEKVGTLVIPD
HHHHHCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA