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The map label for this gene is fba [H]

Identifier: 239618023

GI number: 239618023

Start: 1780160

End: 1781104

Strand: Reverse

Name: fba [H]

Synonym: Kole_1652

Alternate gene names: 239618023

Gene position: 1781104-1780160 (Counterclockwise)

Preceding gene: 239618024

Following gene: 239618022

Centisome position: 77.37

GC content: 39.58

Gene sequence:

>945_bases
ATGCCGTATGTCAACACAAAAGATATTCTTGAAAAGGCGAGTAAAGAGGGTTATGCTGTTCCAGCGCTAAATATCAACAA
TCTTGAGTTTCTACACGCTATTATTGACGCGGGTATTGAAGAAAATGCACCAATAATCATTGAAACATCTGAAGGTGCGA
TAAAGTACGCTGGAAATGGTGATATCAGAAGAGGAGCACAACTCTTCGTTTCGATGGTAAGAGCTTTTGCAAATACTGTA
CCGGTTCCGGTAGCACTTCATCTGGATCACGGCAAACATTTTAACATTATTATGGAAGCCATTAAAGCAGGATACTCTTC
TGTCATGATAGATGCTTCCGAATACCCCTTTGAGAAAAATCTTGAAGAAACTAAAAAAATAGTGGAAATAGCTCATAGTG
TTGGCGTCTCCGTTGAGGCAGAGCTTGGAAGATTGGTTGGTATAGAAGATAATGTCGTTGTTGCTGAACACGAAGCCGTA
TTAGTTGATCCAAACGAAGCGAAGGAATTTGTTGAAAATACGGGCGTTGATTTCCTTGCTCCAGCTATTGGAACGAGTCA
TGGCGCTTTTAAATTCAAAGGTGAAGCAAAACTGGATTTTGATAGATTGAAGAAGGTCAAAGAGCTCACAGGAATTCCTC
TCGTTCTGCATGGAGCTTCAAGTGTTCCAGAAGATATTGTAAAGCTTGCTGAAAGTTATGGTGCTAACTTCAAAGGAGCC
AAAGGAGTTCCTTCGGATATACTGAAGAAAGCCGTTAAATTTGGAATCAACAAAGTCAATACCGATACAGATCTAAGAAT
GGCATATGTTGCTGGTCTTAGAGAATTCTTAACCAACAATCCTGGCGAATTTGACCCGAGAAAATATTTCAAGACAGCTA
AGGAATACGTTAAAGAAGTTATCAAAGCACGAATGAGACTATTAGGTTGTTCAAATAAAGCCTGA

Upstream 100 bases:

>100_bases
AATGGAGAGCAAACATTGTATGAAAACATCGGTTACACGTGTAAGCATATTCTGACATAAATATTGAGATGTTATAATCA
TAACCGAAGGAGGGGATATT

Downstream 100 bases:

>100_bases
ATCTGCTGGAGGTGGCGTTGGTGAAAATTCTCGTTGTTAACTGCGGATCCTCATCAATAAAGTACCAGCTGCTCGATATG
AAGAACGAATTAGTTCTGGC

Product: fructose-1,6-bisphosphate aldolase, class II

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPYVNTKDILEKASKEGYAVPALNINNLEFLHAIIDAGIEENAPIIIETSEGAIKYAGNGDIRRGAQLFVSMVRAFANTV
PVPVALHLDHGKHFNIIMEAIKAGYSSVMIDASEYPFEKNLEETKKIVEIAHSVGVSVEAELGRLVGIEDNVVVAEHEAV
LVDPNEAKEFVENTGVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTGIPLVLHGASSVPEDIVKLAESYGANFKGA
KGVPSDILKKAVKFGINKVNTDTDLRMAYVAGLREFLTNNPGEFDPRKYFKTAKEYVKEVIKARMRLLGCSNKA

Sequences:

>Translated_314_residues
MPYVNTKDILEKASKEGYAVPALNINNLEFLHAIIDAGIEENAPIIIETSEGAIKYAGNGDIRRGAQLFVSMVRAFANTV
PVPVALHLDHGKHFNIIMEAIKAGYSSVMIDASEYPFEKNLEETKKIVEIAHSVGVSVEAELGRLVGIEDNVVVAEHEAV
LVDPNEAKEFVENTGVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTGIPLVLHGASSVPEDIVKLAESYGANFKGA
KGVPSDILKKAVKFGINKVNTDTDLRMAYVAGLREFLTNNPGEFDPRKYFKTAKEYVKEVIKARMRLLGCSNKA
>Mature_313_residues
PYVNTKDILEKASKEGYAVPALNINNLEFLHAIIDAGIEENAPIIIETSEGAIKYAGNGDIRRGAQLFVSMVRAFANTVP
VPVALHLDHGKHFNIIMEAIKAGYSSVMIDASEYPFEKNLEETKKIVEIAHSVGVSVEAELGRLVGIEDNVVVAEHEAVL
VDPNEAKEFVENTGVDFLAPAIGTSHGAFKFKGEAKLDFDRLKKVKELTGIPLVLHGASSVPEDIVKLAESYGANFKGAK
GVPSDILKKAVKFGINKVNTDTDLRMAYVAGLREFLTNNPGEFDPRKYFKTAKEYVKEVIKARMRLLGCSNKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=313, Percent_Identity=37.3801916932907, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI87082041, Length=314, Percent_Identity=37.2611464968153, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1788072, Length=302, Percent_Identity=35.7615894039735, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789293, Length=336, Percent_Identity=24.1071428571429, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=341, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 34286; Mature: 34155

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00602 ALDOLASE_CLASS_II_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYVNTKDILEKASKEGYAVPALNINNLEFLHAIIDAGIEENAPIIIETSEGAIKYAGNG
CCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCC
DIRRGAQLFVSMVRAFANTVPVPVALHLDHGKHFNIIMEAIKAGYSSVMIDASEYPFEKN
CHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEEECCCCCCCCC
LEETKKIVEIAHSVGVSVEAELGRLVGIEDNVVVAEHEAVLVDPNEAKEFVENTGVDFLA
HHHHHHHHHHHHHHCCEEEHHHHHEECCCCCEEEEECCEEEECCHHHHHHHHHCCCHHHH
PAIGTSHGAFKFKGEAKLDFDRLKKVKELTGIPLVLHGASSVPEDIVKLAESYGANFKGA
HHHCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCC
KGVPSDILKKAVKFGINKVNTDTDLRMAYVAGLREFLTNNPGEFDPRKYFKTAKEYVKEV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IKARMRLLGCSNKA
HHHHHHHHCCCCCC
>Mature Secondary Structure 
PYVNTKDILEKASKEGYAVPALNINNLEFLHAIIDAGIEENAPIIIETSEGAIKYAGNG
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCC
DIRRGAQLFVSMVRAFANTVPVPVALHLDHGKHFNIIMEAIKAGYSSVMIDASEYPFEKN
CHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEEECCCCCCCCC
LEETKKIVEIAHSVGVSVEAELGRLVGIEDNVVVAEHEAVLVDPNEAKEFVENTGVDFLA
HHHHHHHHHHHHHHCCEEEHHHHHEECCCCCEEEEECCEEEECCHHHHHHHHHCCCHHHH
PAIGTSHGAFKFKGEAKLDFDRLKKVKELTGIPLVLHGASSVPEDIVKLAESYGANFKGA
HHHCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCC
KGVPSDILKKAVKFGINKVNTDTDLRMAYVAGLREFLTNNPGEFDPRKYFKTAKEYVKEV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IKARMRLLGCSNKA
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]