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The map label for this gene is ackA [H]

Identifier: 239618022

GI number: 239618022

Start: 1778916

End: 1780139

Strand: Reverse

Name: ackA [H]

Synonym: Kole_1651

Alternate gene names: 239618022

Gene position: 1780139-1778916 (Counterclockwise)

Preceding gene: 239618023

Following gene: 239618021

Centisome position: 77.33

GC content: 43.14

Gene sequence:

>1224_bases
GTGAAAATTCTCGTTGTTAACTGCGGATCCTCATCAATAAAGTACCAGCTGCTCGATATGAAGAACGAATTAGTTCTGGC
AAAGGGCATCGTTGAAAGAATCGGAATCGATGGTTCAAGGCTCAAACACAAAAAAGGGAAAGAAAAGATCACCATTGAAA
AAGTAATCTCCAATCACAAAGAAGGGCTCGATCTCGTTATTAAAACACTTACAGACAAAGAAACAGGTGTTATTGAAAAT
ATCAATGAAATCGATGCCGTCGGTCACAGGGTGGTCCATGGTGGAGAATTATTCGCTTCCTCTGTTTTGATAGATGACAG
GGTAATCAAAGAGATCGAAGCGAACGCTTTTCTTGCTCCTCTTCACAACCCACCAAACATTCAGGGTATAAAAGCGGCCA
TGGAATTATTGCCAGATGTCCCTCATGTAGCGGTATTTGACACAGCCTTTCACCAGTCAATGCCGGAAAAAGCTTATCTA
TACGCTATCCCGAAAGAATACTATCGAAAGTACAAGATCAGAAGGTACGGATTTCACGGTACCAGCCACAGATATGTAGC
TGCAAGAGTAGCAGAAATCCTCGGGAAACCCTTAAATGAATTAAAAATAATAACCGCTCATATCGGGAACGGAGCTTCAA
TTGCCGCAATAGATCGCGGTCGTTCTGTCGATACATCTATGGGATTTACCCCCCTTGAAGGGCTCGTTATGGGCACCAGA
AGCGGTGACATTGATCCAGCAATTGTCGTTTTCCTTCAGGAACAGGAAGGCTTAACCCCGAAAGAAATTAACGATCTGCT
GAATAAAAAAAGCGGAATGCTTGGCCTAACGGACGGTAAATACAGCGACATGCGTGAGATAGAAGAAGGTGCTATTGCCA
ACGATCCTGTGTGTAAACTCGCTCACGATATCTACGAATACAGAATAGCCAAATACATAGGCGCATACACCGCTGCTATG
AACGGTGTTGACGCGATAGCCTTCACCGCTGGTGTCGGCGAAAACAGCCCTTATCTTCGTGAGAATGTCGTCAAAAAATA
TCTTGGTTACTTAGGAATCACCCTGGATGAAAAAGCAAACGACTGTAAATCCTGTGAGAAAATCATCTCCACTCCTGATT
CTAAAGTAAAAGTCCTCATCGTTCCGACAAACGAGGAACTTGTGATAGCAAGAGACACTAAAGAAATCGTTGAGAAGGGT
ATCAAAGAATTGAAACTGTGGTAA

Upstream 100 bases:

>100_bases
ATTTCAAGACAGCTAAGGAATACGTTAAAGAAGTTATCAAAGCACGAATGAGACTATTAGGTTGTTCAAATAAAGCCTGA
ATCTGCTGGAGGTGGCGTTG

Downstream 100 bases:

>100_bases
TCTGTCAGCCGTGCGCCGAATTGGCGCACGGTATTTCTAAATTTCTGTGAAGAGGCAGGTGTCAAAGTGAAAGAAGTCAC
CTTTGAAGCAGACAAAAAGA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKILVVNCGSSSIKYQLLDMKNELVLAKGIVERIGIDGSRLKHKKGKEKITIEKVISNHKEGLDLVIKTLTDKETGVIEN
INEIDAVGHRVVHGGELFASSVLIDDRVIKEIEANAFLAPLHNPPNIQGIKAAMELLPDVPHVAVFDTAFHQSMPEKAYL
YAIPKEYYRKYKIRRYGFHGTSHRYVAARVAEILGKPLNELKIITAHIGNGASIAAIDRGRSVDTSMGFTPLEGLVMGTR
SGDIDPAIVVFLQEQEGLTPKEINDLLNKKSGMLGLTDGKYSDMREIEEGAIANDPVCKLAHDIYEYRIAKYIGAYTAAM
NGVDAIAFTAGVGENSPYLRENVVKKYLGYLGITLDEKANDCKSCEKIISTPDSKVKVLIVPTNEELVIARDTKEIVEKG
IKELKLW

Sequences:

>Translated_407_residues
MKILVVNCGSSSIKYQLLDMKNELVLAKGIVERIGIDGSRLKHKKGKEKITIEKVISNHKEGLDLVIKTLTDKETGVIEN
INEIDAVGHRVVHGGELFASSVLIDDRVIKEIEANAFLAPLHNPPNIQGIKAAMELLPDVPHVAVFDTAFHQSMPEKAYL
YAIPKEYYRKYKIRRYGFHGTSHRYVAARVAEILGKPLNELKIITAHIGNGASIAAIDRGRSVDTSMGFTPLEGLVMGTR
SGDIDPAIVVFLQEQEGLTPKEINDLLNKKSGMLGLTDGKYSDMREIEEGAIANDPVCKLAHDIYEYRIAKYIGAYTAAM
NGVDAIAFTAGVGENSPYLRENVVKKYLGYLGITLDEKANDCKSCEKIISTPDSKVKVLIVPTNEELVIARDTKEIVEKG
IKELKLW
>Mature_407_residues
MKILVVNCGSSSIKYQLLDMKNELVLAKGIVERIGIDGSRLKHKKGKEKITIEKVISNHKEGLDLVIKTLTDKETGVIEN
INEIDAVGHRVVHGGELFASSVLIDDRVIKEIEANAFLAPLHNPPNIQGIKAAMELLPDVPHVAVFDTAFHQSMPEKAYL
YAIPKEYYRKYKIRRYGFHGTSHRYVAARVAEILGKPLNELKIITAHIGNGASIAAIDRGRSVDTSMGFTPLEGLVMGTR
SGDIDPAIVVFLQEQEGLTPKEINDLLNKKSGMLGLTDGKYSDMREIEEGAIANDPVCKLAHDIYEYRIAKYIGAYTAAM
NGVDAIAFTAGVGENSPYLRENVVKKYLGYLGITLDEKANDCKSCEKIISTPDSKVKVLIVPTNEELVIARDTKEIVEKG
IKELKLW

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=46.6334164588529, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI145693184, Length=395, Percent_Identity=41.7721518987342, Blast_Score=305, Evalue=5e-84,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44942; Mature: 44942

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVVNCGSSSIKYQLLDMKNELVLAKGIVERIGIDGSRLKHKKGKEKITIEKVISNHK
CEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCC
EGLDLVIKTLTDKETGVIENINEIDAVGHRVVHGGELFASSVLIDDRVIKEIEANAFLAP
CCHHHHHHHHCCCCCCHHHCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCEEEEE
LHNPPNIQGIKAAMELLPDVPHVAVFDTAFHQSMPEKAYLYAIPKEYYRKYKIRRYGFHG
CCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEEEECCHHHHHHHHHHEECCCC
TSHRYVAARVAEILGKPLNELKIITAHIGNGASIAAIDRGRSVDTSMGFTPLEGLVMGTR
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC
SGDIDPAIVVFLQEQEGLTPKEINDLLNKKSGMLGLTDGKYSDMREIEEGAIANDPVCKL
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCHHHHH
AHDIYEYRIAKYIGAYTAAMNGVDAIAFTAGVGENSPYLRENVVKKYLGYLGITLDEKAN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEECCCCC
DCKSCEKIISTPDSKVKVLIVPTNEELVIARDTKEIVEKGIKELKLW
HHHHHHHHHCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILVVNCGSSSIKYQLLDMKNELVLAKGIVERIGIDGSRLKHKKGKEKITIEKVISNHK
CEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCC
EGLDLVIKTLTDKETGVIENINEIDAVGHRVVHGGELFASSVLIDDRVIKEIEANAFLAP
CCHHHHHHHHCCCCCCHHHCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCEEEEE
LHNPPNIQGIKAAMELLPDVPHVAVFDTAFHQSMPEKAYLYAIPKEYYRKYKIRRYGFHG
CCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCEEEEECCHHHHHHHHHHEECCCC
TSHRYVAARVAEILGKPLNELKIITAHIGNGASIAAIDRGRSVDTSMGFTPLEGLVMGTR
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC
SGDIDPAIVVFLQEQEGLTPKEINDLLNKKSGMLGLTDGKYSDMREIEEGAIANDPVCKL
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCHHHHH
AHDIYEYRIAKYIGAYTAAMNGVDAIAFTAGVGENSPYLRENVVKKYLGYLGITLDEKAN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEECCCCC
DCKSCEKIISTPDSKVKVLIVPTNEELVIARDTKEIVEKGIKELKLW
HHHHHHHHHCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA