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The map label for this gene is frr

Identifier: 239617981

GI number: 239617981

Start: 1726386

End: 1726943

Strand: Reverse

Name: frr

Synonym: Kole_1609

Alternate gene names: 239617981

Gene position: 1726943-1726386 (Counterclockwise)

Preceding gene: 239617988

Following gene: 239617980

Centisome position: 75.02

GC content: 40.86

Gene sequence:

>558_bases
ATGAAAAATATGCTTCTGAAAGATGCTGAAGAGCGCATGAAAAAAAGCACAGAAAAAATCTCTGAAGAGTTCAGCCATAT
GAGAACCGGAAGACCTTCGCCTGCAATCCTCGAGGAAATCAAGGTGGATTATTATGGCGTTCCTACCCCCATTAATCAGT
TAGCAACGATAAATGTTAGTGAGGATAGGTCTTTAATCATCAGGCCGTGGGAAAAGAACATGCTCTCCCATATTGAAAAA
GCTATATTGGCCTCTAATCTGGGATTGACCCCCATCAACGATGGTAACGTTGTGCGACTGAATTTCCCCATTCCGACAAC
TGAACAGAGGGAAAAATGGGTAAAACTGAGCAAAGAGATCGCTGAAAAGGGAAAAATAGCGGTCAGGAACATCAGGCGTG
ACGTTCTAAAGGAAGCTAAAGAAATGGAAAAGAACAAGGAAATGACAGAAGACGATCTTCGAAGATTTGAGGAAGAGCTC
CAAAAGTTGACCGACAAATACGTTGAAGAAATGGATAAGCTTTTTGAGAAAAAGAAAAAGGAAATCATGGAGTTTTAA

Upstream 100 bases:

>100_bases
TACAGCTTATCGTCTGCCAAATTGAAATCAGCATTGTTGCCACTAAAGCTGTGATATAATTTGGGTTGAATATTCAACAA
CATGAAAGGAGGAATAAATA

Downstream 100 bases:

>100_bases
AGCAGATGAAGATACCTACTCATATTGCTATCATAATGGATGGCAACGGTCGCTGGGCCAAACAAAGAGGATTACGGAGA
ACGGAAGGGCATAAAAAAGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKNMLLKDAEERMKKSTEKISEEFSHMRTGRPSPAILEEIKVDYYGVPTPINQLATINVSEDRSLIIRPWEKNMLSHIEK
AILASNLGLTPINDGNVVRLNFPIPTTEQREKWVKLSKEIAEKGKIAVRNIRRDVLKEAKEMEKNKEMTEDDLRRFEEEL
QKLTDKYVEEMDKLFEKKKKEIMEF

Sequences:

>Translated_185_residues
MKNMLLKDAEERMKKSTEKISEEFSHMRTGRPSPAILEEIKVDYYGVPTPINQLATINVSEDRSLIIRPWEKNMLSHIEK
AILASNLGLTPINDGNVVRLNFPIPTTEQREKWVKLSKEIAEKGKIAVRNIRRDVLKEAKEMEKNKEMTEDDLRRFEEEL
QKLTDKYVEEMDKLFEKKKKEIMEF
>Mature_185_residues
MKNMLLKDAEERMKKSTEKISEEFSHMRTGRPSPAILEEIKVDYYGVPTPINQLATINVSEDRSLIIRPWEKNMLSHIEK
AILASNLGLTPINDGNVVRLNFPIPTTEQREKWVKLSKEIAEKGKIAVRNIRRDVLKEAKEMEKNKEMTEDDLRRFEEEL
QKLTDKYVEEMDKLFEKKKKEIMEF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=185, Percent_Identity=29.1891891891892, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=42.4581005586592, Blast_Score=158, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321827, Length=190, Percent_Identity=27.8947368421053, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_KOSOT (C5CF34)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941303.1
- GeneID:   7967841
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1609
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21794; Mature: 21794

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMLLKDAEERMKKSTEKISEEFSHMRTGRPSPAILEEIKVDYYGVPTPINQLATINVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCC
EDRSLIIRPWEKNMLSHIEKAILASNLGLTPINDGNVVRLNFPIPTTEQREKWVKLSKEI
CCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AEKGKIAVRNIRRDVLKEAKEMEKNKEMTEDDLRRFEEELQKLTDKYVEEMDKLFEKKKK
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEF
HHHCC
>Mature Secondary Structure
MKNMLLKDAEERMKKSTEKISEEFSHMRTGRPSPAILEEIKVDYYGVPTPINQLATINVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCC
EDRSLIIRPWEKNMLSHIEKAILASNLGLTPINDGNVVRLNFPIPTTEQREKWVKLSKEI
CCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AEKGKIAVRNIRRDVLKEAKEMEKNKEMTEDDLRRFEEELQKLTDKYVEEMDKLFEKKKK
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA