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The map label for this gene is appC [H]

Identifier: 239617881

GI number: 239617881

Start: 1617500

End: 1619149

Strand: Reverse

Name: appC [H]

Synonym: Kole_1509

Alternate gene names: 239617881

Gene position: 1619149-1617500 (Counterclockwise)

Preceding gene: 239617882

Following gene: 239617880

Centisome position: 70.33

GC content: 45.27

Gene sequence:

>1650_bases
TTGAAAAAACAAAAAGCAGTTATAAAAACAGAAGATGTAAAAAAAGATGATTTGTTCGAAGTTGAATACATGAACCGCTG
GCAACTCGCCTGGAGAGTCCTAAGGCGCCATAAGCTTGGTATGATCTCACTTTGGGTTCTCATAATCATGTACCTGGTTG
CCATATTCGCAGATTTCCTTTCTCCGCACGACCCGTATGAACAATGGCAGGGCTTGTCCTATTCTCCCCCTTCCAACATC
CACTGGAAGGATGAAGATGGGAAATTCACCCGCCCCTATGTTTATCCCTACGTTCTCGAAAGGGATCCAGTGACGTACAA
AACAACCTTTGCAGAGGGGTCATCTCTGCAAAGTATTACTGCGATTGATGAATCAACAGGTGAAAAGAAGGTCTTCACAA
TTGGAAATGATGACGTTAGATCTATATATCTTGTGGTGGAGACCATTAGATATGCTGAAGACGCCAAAGGTAAGAAAGCA
ATATTAGGGAATCCAGACTATAAGACCCTGGAAATAGTCAAACTATCGGAAATCGGTATGCTGAAAGAACCTTTGTTCCA
GGAAAACACCAGCGAAGATGTTCTCAACGCCCTGGCTCCAAACAAATATAGAACCCTCAGAAATATCGGTGATCCCGTAA
AGGTTGTCACTGAGAAAAGGCTTCACAGGATCTATGCTGTAAAAAAGGATGAAGTAAGAGACGTGGTAACAGAAGCCATA
AGTCTGGTTAATGAAATAATAGATGTCGAAGGCGGGGATTTTGAACTGGCAAAGGAATTTCTCGCCGAACTGGACATAGA
TCCTGAGCTTTTCGATGTGGTAGTCACCCCAAAAGTAGTGGACTTCGAAATGAGGAAATTCCCACTAAAGTTTTTCGTTC
GCTCCTGGGAATACAAACTCCTCTGGCTCATCCCCATGGATATCCATTTAATAGGAGTTGATGACCCGGCGAGAATCTAT
TTCTTCGGTGGAGATAAATTCGGACGAGACGTATTCTCGAGAATTCTATTCGGCTCGAGAATCTCCATGTCTATCGGTCT
CTTGGCTATCATGATAACCTTCACGCTCGGTTTGTTCATAGGTGGAGTTGCAGGATACTACGGTGGATGGGTTGATGAAA
GTCTCATGAGAATGACGGAAATATTGATGTCAATCCCTGGATTCTACCTGTTGATATCCCTTAGAGCCATACTGCCGACC
AATCTCCCCTCACACATAACCTATCTGCTCATCGTTGTCATCCTCAGTTTCCTTGGTTGGCCCGGTATGTCCAGGGTCAT
ACGTGGTATGGTACTTTCGTTAAAAGAAAGGGAATTCGTTCAGGCAGCAATCGCAATGGGATATCCATCAAGCCGGATCA
TCTGGAAACACATCATTCCGAATACCGCAACCTACATCATCGTATCTGCAACCCTGTCTATACCCGGATACATACTCGGT
GAGGCTGGACTCAGCTTCCTTGGGCTCGGGATCATGGAACCTTCTGCCAGCTGGGGATTGATGCTGAGTCAGGCTCAGAA
TATAAAGGTTATGACGGAAGCGCCGTGGCTTCTCGTACCCGGTATCTTCATCTTTATCGTTGTTATGGCGTTCAACCTGC
TTGGTGACGCCCTGAGAGATGCGCTTGACCCGAGATCTCTGGGTTACTGA

Upstream 100 bases:

>100_bases
CGCTGTTGCTGATAGCTGGTAACCTGGTTGCAGACCTTCTCCTTGCCTGGGTAGATCCAAGAATCAGATTCAGATTGAGA
TAGTCAGGAGTGATGTGGCC

Downstream 100 bases:

>100_bases
TATAAGGAGATGTAAGATAGGAGAAGAGCACCACCTTCCAACAGTAAAGACTAATAATGATCTGGTGAGGTCCCTTGTGG
ACCTCACTTTTTACAGTCAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKKQKAVIKTEDVKKDDLFEVEYMNRWQLAWRVLRRHKLGMISLWVLIIMYLVAIFADFLSPHDPYEQWQGLSYSPPSNI
HWKDEDGKFTRPYVYPYVLERDPVTYKTTFAEGSSLQSITAIDESTGEKKVFTIGNDDVRSIYLVVETIRYAEDAKGKKA
ILGNPDYKTLEIVKLSEIGMLKEPLFQENTSEDVLNALAPNKYRTLRNIGDPVKVVTEKRLHRIYAVKKDEVRDVVTEAI
SLVNEIIDVEGGDFELAKEFLAELDIDPELFDVVVTPKVVDFEMRKFPLKFFVRSWEYKLLWLIPMDIHLIGVDDPARIY
FFGGDKFGRDVFSRILFGSRISMSIGLLAIMITFTLGLFIGGVAGYYGGWVDESLMRMTEILMSIPGFYLLISLRAILPT
NLPSHITYLLIVVILSFLGWPGMSRVIRGMVLSLKEREFVQAAIAMGYPSSRIIWKHIIPNTATYIIVSATLSIPGYILG
EAGLSFLGLGIMEPSASWGLMLSQAQNIKVMTEAPWLLVPGIFIFIVVMAFNLLGDALRDALDPRSLGY

Sequences:

>Translated_549_residues
MKKQKAVIKTEDVKKDDLFEVEYMNRWQLAWRVLRRHKLGMISLWVLIIMYLVAIFADFLSPHDPYEQWQGLSYSPPSNI
HWKDEDGKFTRPYVYPYVLERDPVTYKTTFAEGSSLQSITAIDESTGEKKVFTIGNDDVRSIYLVVETIRYAEDAKGKKA
ILGNPDYKTLEIVKLSEIGMLKEPLFQENTSEDVLNALAPNKYRTLRNIGDPVKVVTEKRLHRIYAVKKDEVRDVVTEAI
SLVNEIIDVEGGDFELAKEFLAELDIDPELFDVVVTPKVVDFEMRKFPLKFFVRSWEYKLLWLIPMDIHLIGVDDPARIY
FFGGDKFGRDVFSRILFGSRISMSIGLLAIMITFTLGLFIGGVAGYYGGWVDESLMRMTEILMSIPGFYLLISLRAILPT
NLPSHITYLLIVVILSFLGWPGMSRVIRGMVLSLKEREFVQAAIAMGYPSSRIIWKHIIPNTATYIIVSATLSIPGYILG
EAGLSFLGLGIMEPSASWGLMLSQAQNIKVMTEAPWLLVPGIFIFIVVMAFNLLGDALRDALDPRSLGY
>Mature_549_residues
MKKQKAVIKTEDVKKDDLFEVEYMNRWQLAWRVLRRHKLGMISLWVLIIMYLVAIFADFLSPHDPYEQWQGLSYSPPSNI
HWKDEDGKFTRPYVYPYVLERDPVTYKTTFAEGSSLQSITAIDESTGEKKVFTIGNDDVRSIYLVVETIRYAEDAKGKKA
ILGNPDYKTLEIVKLSEIGMLKEPLFQENTSEDVLNALAPNKYRTLRNIGDPVKVVTEKRLHRIYAVKKDEVRDVVTEAI
SLVNEIIDVEGGDFELAKEFLAELDIDPELFDVVVTPKVVDFEMRKFPLKFFVRSWEYKLLWLIPMDIHLIGVDDPARIY
FFGGDKFGRDVFSRILFGSRISMSIGLLAIMITFTLGLFIGGVAGYYGGWVDESLMRMTEILMSIPGFYLLISLRAILPT
NLPSHITYLLIVVILSFLGWPGMSRVIRGMVLSLKEREFVQAAIAMGYPSSRIIWKHIIPNTATYIIVSATLSIPGYILG
EAGLSFLGLGIMEPSASWGLMLSQAQNIKVMTEAPWLLVPGIFIFIVVMAFNLLGDALRDALDPRSLGY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=236, Percent_Identity=38.5593220338983, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1787498, Length=227, Percent_Identity=41.8502202643172, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=38, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1787760, Length=233, Percent_Identity=36.9098712446352, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789964, Length=228, Percent_Identity=35.9649122807018, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788505, Length=236, Percent_Identity=32.6271186440678, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1787549, Length=224, Percent_Identity=33.4821428571429, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 62364; Mature: 62364

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQKAVIKTEDVKKDDLFEVEYMNRWQLAWRVLRRHKLGMISLWVLIIMYLVAIFADFL
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SPHDPYEQWQGLSYSPPSNIHWKDEDGKFTRPYVYPYVLERDPVTYKTTFAEGSSLQSIT
CCCCCHHHHCCCCCCCCCCCEEECCCCCEECCEEEEEEEECCCCEEEEEECCCCCCCCEE
AIDESTGEKKVFTIGNDDVRSIYLVVETIRYAEDAKGKKAILGNPDYKTLEIVKLSEIGM
EHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEHHCCC
LKEPLFQENTSEDVLNALAPNKYRTLRNIGDPVKVVTEKRLHRIYAVKKDEVRDVVTEAI
HHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SLVNEIIDVEGGDFELAKEFLAELDIDPELFDVVVTPKVVDFEMRKFPLKFFVRSWEYKL
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHEEEEECCCEECHHHHHHHHHHHHHCCCEEE
LWLIPMDIHLIGVDDPARIYFFGGDKFGRDVFSRILFGSRISMSIGLLAIMITFTLGLFI
EEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GGVAGYYGGWVDESLMRMTEILMSIPGFYLLISLRAILPTNLPSHITYLLIVVILSFLGW
HHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
PGMSRVIRGMVLSLKEREFVQAAIAMGYPSSRIIWKHIIPNTATYIIVSATLSIPGYILG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCEEEEEEEEEECCCCEEEH
EAGLSFLGLGIMEPSASWGLMLSQAQNIKVMTEAPWLLVPGIFIFIVVMAFNLLGDALRD
HHCHHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALDPRSLGY
HCCCCCCCC
>Mature Secondary Structure
MKKQKAVIKTEDVKKDDLFEVEYMNRWQLAWRVLRRHKLGMISLWVLIIMYLVAIFADFL
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SPHDPYEQWQGLSYSPPSNIHWKDEDGKFTRPYVYPYVLERDPVTYKTTFAEGSSLQSIT
CCCCCHHHHCCCCCCCCCCCEEECCCCCEECCEEEEEEEECCCCEEEEEECCCCCCCCEE
AIDESTGEKKVFTIGNDDVRSIYLVVETIRYAEDAKGKKAILGNPDYKTLEIVKLSEIGM
EHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEHHCCC
LKEPLFQENTSEDVLNALAPNKYRTLRNIGDPVKVVTEKRLHRIYAVKKDEVRDVVTEAI
HHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SLVNEIIDVEGGDFELAKEFLAELDIDPELFDVVVTPKVVDFEMRKFPLKFFVRSWEYKL
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHEEEEECCCEECHHHHHHHHHHHHHCCCEEE
LWLIPMDIHLIGVDDPARIYFFGGDKFGRDVFSRILFGSRISMSIGLLAIMITFTLGLFI
EEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GGVAGYYGGWVDESLMRMTEILMSIPGFYLLISLRAILPTNLPSHITYLLIVVILSFLGW
HHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
PGMSRVIRGMVLSLKEREFVQAAIAMGYPSSRIIWKHIIPNTATYIIVSATLSIPGYILG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCEEEEEEEEEECCCCEEEH
EAGLSFLGLGIMEPSASWGLMLSQAQNIKVMTEAPWLLVPGIFIFIVVMAFNLLGDALRD
HHCHHHHCCCCCCCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALDPRSLGY
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]