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The map label for this gene is lacC [H]

Identifier: 239617243

GI number: 239617243

Start: 900199

End: 901125

Strand: Reverse

Name: lacC [H]

Synonym: Kole_0851

Alternate gene names: 239617243

Gene position: 901125-900199 (Counterclockwise)

Preceding gene: 239617244

Following gene: 239617239

Centisome position: 39.14

GC content: 43.04

Gene sequence:

>927_bases
ATGATTTTCACTTTAACACTAAATCCATGTCTGGATAGATACCTTTACATCGATGATTTAATAGAAGACGATACTGTTCG
TGTTAAAAAAGTTAGTGATTATCCTGCTGGTAAAGGAATCGATGTTTCGCGCGTTATAAATGAACTCGGAGGCCATTCAG
TCGCTATTGCATTACTCGGTGGGCATACGGGACAAATCATACAAAAAATGCTCAATGAAGAGGGTGTCGTTTACGCTTCG
GTTTTCACCCACAAAGAAACGAGGGTCAACACCATACTTCAAAAGGGCAACACACAGTACCGTATGAGCCTCCCGGGACC
GGAAGTATCCGATGAAGAAGAAAGGAAGATTATAAAGACTATCGATACCTTACTCAGGCAAGGAGATTTTTTGATACTCT
CCGGAAGCCTCGCGAAAGGAATAAAAAGTTCTATTTACCTGGAAATTTGCAAATTTGCTAAAAAAAGAGGCGCAAAAGTA
TACCTCGATTCAGACGGGAAACCCTTAATGCTGGGGATAAAATGCCCACCAGACGGGATTAAGCCCAATCTTCATGAATT
CTCGCGCCTTTATGGAAAAGTACCTGAAAGTCACGAAGAACTGAAAGACGCGCTAATAGAGGTAAGCAAGAAGTACGGGA
TAAACGAGATTCTGCTGACATTGGGAAAAGACGGAGCTCTTTGTTACGTCGATAATTCACTCTATCGTGTTAGCGTTCCT
GAAGTTCCGGTTAAAAGTGCAGTTGGTGCTGGCGATAGTTTCCTTGCCGCTTACTGTATGTACAGAGAAGCAGGAAAACC
TATCGAAGAAGCTCTCAGGGTGGCGGGCGCGGCCAGCAGTGCTACAGTAATAACACCCGGTACAGAACTTTGCCATAAAA
AAGATGTCGAAAAACTTATGAAAGATGTACAGGTAGAGCGACTTTGA

Upstream 100 bases:

>100_bases
TTGGAGCAGATAATAGCCAAGCTTGCCGAGACTGCGAAACATAGATATATGCAAATCCTGCACGATGAAGACAGAACGGA
TATGTTCAGGAGATGACAGG

Downstream 100 bases:

>100_bases
TGATTGAGACAAAGAACGAGAGCGGGTGCTGGAGACTGGAGAAAGCTGCTTTGCAGCGGCACGAATCTCTTCGAGATTGT
CACGACCGGCTTCGCCAGTG

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Phosphotagatokinase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIFTLTLNPCLDRYLYIDDLIEDDTVRVKKVSDYPAGKGIDVSRVINELGGHSVAIALLGGHTGQIIQKMLNEEGVVYAS
VFTHKETRVNTILQKGNTQYRMSLPGPEVSDEEERKIIKTIDTLLRQGDFLILSGSLAKGIKSSIYLEICKFAKKRGAKV
YLDSDGKPLMLGIKCPPDGIKPNLHEFSRLYGKVPESHEELKDALIEVSKKYGINEILLTLGKDGALCYVDNSLYRVSVP
EVPVKSAVGAGDSFLAAYCMYREAGKPIEEALRVAGAASSATVITPGTELCHKKDVEKLMKDVQVERL

Sequences:

>Translated_308_residues
MIFTLTLNPCLDRYLYIDDLIEDDTVRVKKVSDYPAGKGIDVSRVINELGGHSVAIALLGGHTGQIIQKMLNEEGVVYAS
VFTHKETRVNTILQKGNTQYRMSLPGPEVSDEEERKIIKTIDTLLRQGDFLILSGSLAKGIKSSIYLEICKFAKKRGAKV
YLDSDGKPLMLGIKCPPDGIKPNLHEFSRLYGKVPESHEELKDALIEVSKKYGINEILLTLGKDGALCYVDNSLYRVSVP
EVPVKSAVGAGDSFLAAYCMYREAGKPIEEALRVAGAASSATVITPGTELCHKKDVEKLMKDVQVERL
>Mature_308_residues
MIFTLTLNPCLDRYLYIDDLIEDDTVRVKKVSDYPAGKGIDVSRVINELGGHSVAIALLGGHTGQIIQKMLNEEGVVYAS
VFTHKETRVNTILQKGNTQYRMSLPGPEVSDEEERKIIKTIDTLLRQGDFLILSGSLAKGIKSSIYLEICKFAKKRGAKV
YLDSDGKPLMLGIKCPPDGIKPNLHEFSRLYGKVPESHEELKDALIEVSKKYGINEILLTLGKDGALCYVDNSLYRVSVP
EVPVKSAVGAGDSFLAAYCMYREAGKPIEEALRVAGAASSATVITPGTELCHKKDVEKLMKDVQVERL

Specific function: Key control step of glycolysis. [C]

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788017, Length=301, Percent_Identity=30.5647840531561, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788493, Length=258, Percent_Identity=27.1317829457364, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: 496 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.144 [H]

Molecular weight: Translated: 33891; Mature: 33891

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFTLTLNPCLDRYLYIDDLIEDDTVRVKKVSDYPAGKGIDVSRVINELGGHSVAIALLG
CEEEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEC
GHTGQIIQKMLNEEGVVYASVFTHKETRVNTILQKGNTQYRMSLPGPEVSDEEERKIIKT
CCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
IDTLLRQGDFLILSGSLAKGIKSSIYLEICKFAKKRGAKVYLDSDGKPLMLGIKCPPDGI
HHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCC
KPNLHEFSRLYGKVPESHEELKDALIEVSKKYGINEILLTLGKDGALCYVDNSLYRVSVP
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEECCEEEEECC
EVPVKSAVGAGDSFLAAYCMYREAGKPIEEALRVAGAASSATVITPGTELCHKKDVEKLM
CCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
KDVQVERL
HHHHHCCC
>Mature Secondary Structure
MIFTLTLNPCLDRYLYIDDLIEDDTVRVKKVSDYPAGKGIDVSRVINELGGHSVAIALLG
CEEEEEECHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEC
GHTGQIIQKMLNEEGVVYASVFTHKETRVNTILQKGNTQYRMSLPGPEVSDEEERKIIKT
CCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
IDTLLRQGDFLILSGSLAKGIKSSIYLEICKFAKKRGAKVYLDSDGKPLMLGIKCPPDGI
HHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCC
KPNLHEFSRLYGKVPESHEELKDALIEVSKKYGINEILLTLGKDGALCYVDNSLYRVSVP
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEECCEEEEECC
EVPVKSAVGAGDSFLAAYCMYREAGKPIEEALRVAGAASSATVITPGTELCHKKDVEKLM
CCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
KDVQVERL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]