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The map label for this gene is ftsA [H]

Identifier: 239616760

GI number: 239616760

Start: 370997

End: 372286

Strand: Direct

Name: ftsA [H]

Synonym: Kole_0353

Alternate gene names: 239616760

Gene position: 370997-372286 (Clockwise)

Preceding gene: 239616759

Following gene: 239616761

Centisome position: 16.12

GC content: 42.71

Gene sequence:

>1290_bases
ATGCCAAGGGGGAAAGAGTACACTGTTTCAATTGACCTCGGTACCAATACGTTAAAGGGGGTTGTGGTCAGTTCAGATCC
TTCTTCACAACTTCAACTTGAAGCTTATGGAAGTGTAAAGTCCGTCGGTCTTGATAAAGGCGAAGTAAAAGATGCGGTGG
CTTTAAAGCAGTCGATCCAGAAACTTGTAGACGACCTCACCGGACAGCTGGGTAAGAAGGACATAGTGGCTGATTTCAGG
CTTTGCTTTACCGACGGTGAGTATGCTGTTATGTCTGAAATCGTTGAAGAATCGATTTCAGACGACAAACCTGTTGTGGT
AACTCAGGAAATCATTGATGAATTGATGGCAAAAATCACTCAAGATAAGCTAAAAGACAATAAAAACATTCATATGAAAT
ATGTGAGAAAGTACATTATCGACGATGAAAAAGTGGTCTTCAATCCGGTGGATATGCTTGCAAAGCAACTAAAAGTTGAA
ATGGTCTTCGTTTCAAGCGAGGGAAAATCAACAGAGGTTTTCAAACGACTTTTCGAAGAACTTCTCGGTACAGGAGATTT
CCTGATCTTCCCATCCTTAATATCCGGTGCTGAAGCAGTCCTAACCGACACCGAAAAGCAACACGGTGTTGTTTGTGTGT
CTATCGGGCATGCTTTTTCTGAATTAGTAATTTATAGAGAGAATCTACCGATTTACGTGTCGCGTATTCCTCTTGGAGTC
AGGCATATCGTTAGGGATATCGCTCTGGTTCTCGGGACCTCTCTTGATGAAGCTGAGCGATTACTCGTAACACACGGCTA
CGCAAGCATGTATCCTCCATCAGGAGATAGTGTCGTAGAATATTTCGGATTAGATGAGAGAACACGAAAGAATGTTTCAG
TGAGAAAATTGTCCACTATAATCTACGCACGTGTTAAAGAACTTTTAAATAAAATCAGACGGGAGATTCAATATTCCAAA
GCCAATTATCCAGAATTCGCCGAAGAAGGAATCCCAGGTGGAGTAGTCTTTACAGGCGGTGGTGCCAAGTTAAGGGGATT
GAGCGACACCGGAGTGGAATCTTTGAAAATGCCAGTAAGGGTAGGAACCTATGAAACCAGTTTTAATCCAAGAATAGAAA
ATGCTCACGACGTCGTGAACGATCCCATATTCAGTAGCTGTCTCGGTAGCCTGATCGTTCAGGACGCTGTGGAAACCGGA
ATAGAAGAAGCTATCGGAAAGCAAAAAAGAAGAGGCTTCGCTGATTTCATAAGGTCTTTGTTCTTTGGAGGTGTTGAGGA
TGAGCTTTGA

Upstream 100 bases:

>100_bases
AAAAACCGGAAATAATACAGAATCTGATCGATAATGCGGAAGATAGGAGTAAATACCTTCTCATGAGTGACGGAAAAATA
TTGAGAGTGAGGTGAAATAG

Downstream 100 bases:

>100_bases
GATGAGCTACGAAGGAAAAGAAACTGATGTGAGACTTCCTGCGATAAAGGTTATTGGTGTTGGTGGTGCTGGCGGTAATG
CAGTAAATAGAATGATCTCT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MPRGKEYTVSIDLGTNTLKGVVVSSDPSSQLQLEAYGSVKSVGLDKGEVKDAVALKQSIQKLVDDLTGQLGKKDIVADFR
LCFTDGEYAVMSEIVEESISDDKPVVVTQEIIDELMAKITQDKLKDNKNIHMKYVRKYIIDDEKVVFNPVDMLAKQLKVE
MVFVSSEGKSTEVFKRLFEELLGTGDFLIFPSLISGAEAVLTDTEKQHGVVCVSIGHAFSELVIYRENLPIYVSRIPLGV
RHIVRDIALVLGTSLDEAERLLVTHGYASMYPPSGDSVVEYFGLDERTRKNVSVRKLSTIIYARVKELLNKIRREIQYSK
ANYPEFAEEGIPGGVVFTGGGAKLRGLSDTGVESLKMPVRVGTYETSFNPRIENAHDVVNDPIFSSCLGSLIVQDAVETG
IEEAIGKQKRRGFADFIRSLFFGGVEDEL

Sequences:

>Translated_429_residues
MPRGKEYTVSIDLGTNTLKGVVVSSDPSSQLQLEAYGSVKSVGLDKGEVKDAVALKQSIQKLVDDLTGQLGKKDIVADFR
LCFTDGEYAVMSEIVEESISDDKPVVVTQEIIDELMAKITQDKLKDNKNIHMKYVRKYIIDDEKVVFNPVDMLAKQLKVE
MVFVSSEGKSTEVFKRLFEELLGTGDFLIFPSLISGAEAVLTDTEKQHGVVCVSIGHAFSELVIYRENLPIYVSRIPLGV
RHIVRDIALVLGTSLDEAERLLVTHGYASMYPPSGDSVVEYFGLDERTRKNVSVRKLSTIIYARVKELLNKIRREIQYSK
ANYPEFAEEGIPGGVVFTGGGAKLRGLSDTGVESLKMPVRVGTYETSFNPRIENAHDVVNDPIFSSCLGSLIVQDAVETG
IEEAIGKQKRRGFADFIRSLFFGGVEDEL
>Mature_428_residues
PRGKEYTVSIDLGTNTLKGVVVSSDPSSQLQLEAYGSVKSVGLDKGEVKDAVALKQSIQKLVDDLTGQLGKKDIVADFRL
CFTDGEYAVMSEIVEESISDDKPVVVTQEIIDELMAKITQDKLKDNKNIHMKYVRKYIIDDEKVVFNPVDMLAKQLKVEM
VFVSSEGKSTEVFKRLFEELLGTGDFLIFPSLISGAEAVLTDTEKQHGVVCVSIGHAFSELVIYRENLPIYVSRIPLGVR
HIVRDIALVLGTSLDEAERLLVTHGYASMYPPSGDSVVEYFGLDERTRKNVSVRKLSTIIYARVKELLNKIRREIQYSKA
NYPEFAEEGIPGGVVFTGGGAKLRGLSDTGVESLKMPVRVGTYETSFNPRIENAHDVVNDPIFSSCLGSLIVQDAVETGI
EEAIGKQKRRGFADFIRSLFFGGVEDEL

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=388, Percent_Identity=24.4845360824742, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 47477; Mature: 47346

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRGKEYTVSIDLGTNTLKGVVVSSDPSSQLQLEAYGSVKSVGLDKGEVKDAVALKQSIQ
CCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHH
KLVDDLTGQLGKKDIVADFRLCFTDGEYAVMSEIVEESISDDKPVVVTQEIIDELMAKIT
HHHHHHHHHCCCHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
QDKLKDNKNIHMKYVRKYIIDDEKVVFNPVDMLAKQLKVEMVFVSSEGKSTEVFKRLFEE
HHHHCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHH
LLGTGDFLIFPSLISGAEAVLTDTEKQHGVVCVSIGHAFSELVIYRENLPIYVSRIPLGV
HHCCCCEEEHHHHHCCCHHEEECCCCCCCEEEEEHHHHHHHHHEEECCCCEEEEECCHHH
RHIVRDIALVLGTSLDEAERLLVTHGYASMYPPSGDSVVEYFGLDERTRKNVSVRKLSTI
HHHHHHHHHHHCCCHHHHHHHEEECCCHHCCCCCCCCHHHHCCCCHHHHCCCHHHHHHHH
IYARVKELLNKIRREIQYSKANYPEFAEEGIPGGVVFTGGGAKLRGLSDTGVESLKMPVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCEECCCCCCCHHHHCCCEE
VGTYETSFNPRIENAHDVVNDPIFSSCLGSLIVQDAVETGIEEAIGKQKRRGFADFIRSL
ECCEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FFGGVEDEL
HCCCCCCCC
>Mature Secondary Structure 
PRGKEYTVSIDLGTNTLKGVVVSSDPSSQLQLEAYGSVKSVGLDKGEVKDAVALKQSIQ
CCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHH
KLVDDLTGQLGKKDIVADFRLCFTDGEYAVMSEIVEESISDDKPVVVTQEIIDELMAKIT
HHHHHHHHHCCCHHHHHHEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
QDKLKDNKNIHMKYVRKYIIDDEKVVFNPVDMLAKQLKVEMVFVSSEGKSTEVFKRLFEE
HHHHCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHH
LLGTGDFLIFPSLISGAEAVLTDTEKQHGVVCVSIGHAFSELVIYRENLPIYVSRIPLGV
HHCCCCEEEHHHHHCCCHHEEECCCCCCCEEEEEHHHHHHHHHEEECCCCEEEEECCHHH
RHIVRDIALVLGTSLDEAERLLVTHGYASMYPPSGDSVVEYFGLDERTRKNVSVRKLSTI
HHHHHHHHHHHCCCHHHHHHHEEECCCHHCCCCCCCCHHHHCCCCHHHHCCCHHHHHHHH
IYARVKELLNKIRREIQYSKANYPEFAEEGIPGGVVFTGGGAKLRGLSDTGVESLKMPVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCEECCCCCCCHHHHCCCEE
VGTYETSFNPRIENAHDVVNDPIFSSCLGSLIVQDAVETGIEEAIGKQKRRGFADFIRSL
ECCEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FFGGVEDEL
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]