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The map label for this gene is dck [H]

Identifier: 239616711

GI number: 239616711

Start: 330733

End: 331347

Strand: Direct

Name: dck [H]

Synonym: Kole_0304

Alternate gene names: 239616711

Gene position: 330733-331347 (Clockwise)

Preceding gene: 239616706

Following gene: 239616712

Centisome position: 14.37

GC content: 39.19

Gene sequence:

>615_bases
ATGGGGAAAATGATTGTTTTTGCAGGAAATGTTGGATCAGGAAAAACAACTATCGCCAGAGCACTTGCAGATGCTCTCGG
CTTTGAGATTCATTTTGAGTCCGTCAGTGATAACCCTTTTCTTGAAGATTTTTATCATAACCAGCGAAAGTGGGCATATC
ATCTACAGACTTTTTTCCTGATTCATAGATTTACAGCACTGAAAGAAGCAATGGAAAAAGGGTCCAACATCGTTTTTGAT
CGCTCTATTTACGAAGATGCGGAGATTTTTGCCAGGAATCTCTACGAAACCGGAAAGATGGAGAAACGCGAATTTGAGAC
TTATCTCGATATGTTCTACTCAATGATCAAATACATCCCACATCCCGACCTGCTCGTATTCATCGATGCCGATATCGATA
CGATACTTGCACGGATAAGAAAAAGAGGCCGTAATATGGAGCTCGAAGTACCAATAGCCTATTGGCAACAGCTTGCAAAT
CTTTATGATTCATGGATAAGTAGGTATGATTATTCGCCAGTGTATAGAATTGATGCAAAATTCGTGGATATTGAAAGATA
TCCAGATCATCTGGACAAAATTGTTTCCGACGTCAAAAGAATTTTGAAGATTTGA

Upstream 100 bases:

>100_bases
AACTGTAATCAACTTAAGTACCGTTTCAAAGTATTACTGCTCATTACATGATAAAATATCGACTGGTTGGGGTAATTTAA
AATATTCGGAGGAATATTTC

Downstream 100 bases:

>100_bases
TTTGTGCGGACGGTGAAGTAGTGATGAAAAGAATTCTTTTATTGCTTTTGATTTTTTCCATAATCCTATCCTTTATGCAA
CTATCTGCAAACGTCAGCAA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MGKMIVFAGNVGSGKTTIARALADALGFEIHFESVSDNPFLEDFYHNQRKWAYHLQTFFLIHRFTALKEAMEKGSNIVFD
RSIYEDAEIFARNLYETGKMEKREFETYLDMFYSMIKYIPHPDLLVFIDADIDTILARIRKRGRNMELEVPIAYWQQLAN
LYDSWISRYDYSPVYRIDAKFVDIERYPDHLDKIVSDVKRILKI

Sequences:

>Translated_204_residues
MGKMIVFAGNVGSGKTTIARALADALGFEIHFESVSDNPFLEDFYHNQRKWAYHLQTFFLIHRFTALKEAMEKGSNIVFD
RSIYEDAEIFARNLYETGKMEKREFETYLDMFYSMIKYIPHPDLLVFIDADIDTILARIRKRGRNMELEVPIAYWQQLAN
LYDSWISRYDYSPVYRIDAKFVDIERYPDHLDKIVSDVKRILKI
>Mature_203_residues
GKMIVFAGNVGSGKTTIARALADALGFEIHFESVSDNPFLEDFYHNQRKWAYHLQTFFLIHRFTALKEAMEKGSNIVFDR
SIYEDAEIFARNLYETGKMEKREFETYLDMFYSMIKYIPHPDLLVFIDADIDTILARIRKRGRNMELEVPIAYWQQLANL
YDSWISRYDYSPVYRIDAKFVDIERYPDHLDKIVSDVKRILKI

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI290656975, Length=181, Percent_Identity=28.1767955801105, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI290656936, Length=181, Percent_Identity=28.1767955801105, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4503269, Length=242, Percent_Identity=26.0330578512397, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4758768, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI290657203, Length=174, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17738037, Length=171, Percent_Identity=27.4853801169591, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 24177; Mature: 24046

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMIVFAGNVGSGKTTIARALADALGFEIHFESVSDNPFLEDFYHNQRKWAYHLQTFFL
CCCEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHH
IHRFTALKEAMEKGSNIVFDRSIYEDAEIFARNLYETGKMEKREFETYLDMFYSMIKYIP
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
HPDLLVFIDADIDTILARIRKRGRNMELEVPIAYWQQLANLYDSWISRYDYSPVYRIDAK
CCCEEEEEECCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEECCE
FVDIERYPDHLDKIVSDVKRILKI
EEEHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKMIVFAGNVGSGKTTIARALADALGFEIHFESVSDNPFLEDFYHNQRKWAYHLQTFFL
CCEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHH
IHRFTALKEAMEKGSNIVFDRSIYEDAEIFARNLYETGKMEKREFETYLDMFYSMIKYIP
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
HPDLLVFIDADIDTILARIRKRGRNMELEVPIAYWQQLANLYDSWISRYDYSPVYRIDAK
CCCEEEEEECCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCEEEECCE
FVDIERYPDHLDKIVSDVKRILKI
EEEHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]