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The map label for this gene is engA

Identifier: 239616622

GI number: 239616622

Start: 244604

End: 245932

Strand: Direct

Name: engA

Synonym: Kole_0215

Alternate gene names: 239616622

Gene position: 244604-245932 (Clockwise)

Preceding gene: 239616621

Following gene: 239616623

Centisome position: 10.63

GC content: 45.67

Gene sequence:

>1329_bases
GTGGCAACAGTCCTCATCGTCGGAAGACCAAATGTCGGAAAATCCACGCTTTTTAACCGCCTTGTTGGTGGAAGGCGTGC
CATAATTGACGACCAGCCTGGTGTTACGCGCGACTTTGTGTTTGGCAGGGTTTTCTGGCAGCATAAGTCTTTCGAGGTTG
TCGATACCTGCGGTTTGTTCGATTCTCCCAAAGATATAATCGAAGAAAAGATGAAAGAAGTCACTCTCGCCCTGCTGAGC
GAGGGTGACCTTTTGCTTTTTGTAGTCGATGGCAGAAAGGGTCTGACATCGGCGGATATGGATATCGCGGAAACACTCAG
AAAATCGAAAAAACGGGTCATTCTGGTAGCGAACAAAGTCGAAAACGTTGACAAATTTACTCTTGAGGTTCTCCCGGAGC
TGTACAGCCTGGGGTTCGGAGAACCTATCCCGATTTCAGCCGAACACGGTTTGAATATCGATGTCCTGCTGGAGAAAATA
ATTAAAACCCTGGAGGAAGCCGGGCATCTGCTGGATTACGAACCCGAAAAGGAAGAAGATAACCTGAAGGTTGCTATCAT
AGGAAAACCGAACGCAGGAAAATCTTCACTTTTCAATTCGATAGTGGGAAGTGACCGCAGCCTCGTCACCGAGATACCTG
GTACCACCCGCGATATGGTTGATGAAACTATCGAAATAGATGGAATGCCTGTCACTTTTATAGACACAGCCGGCATGAGA
AGAAAGTCGAAGGTAGGCGTCAAGAACGTCGAGTATTACAGCGTCATGAGAGCTGTGGATGCAATAGAGCGTTCCGATAT
CTGCATACTCGTCATAGATGCGACACTAGGGATAAGCAATCAGGATCAGAGAATTGCCGGGCTTGTCGAAAAACGCGGTA
AAGGGATAATTACCGTTTTCAATAAGAGTGATCTGTTAAACGAGAAACATAAGGAATCACTACTTTCTTCATTCGAACGG
GAGCTGTATTTCATTGATTATAGCCCTGTTGTTTTTACTTCCGCGACGGAAGGTTTTGGTATCGATGAACTACTGGATAA
GCTCTTTCTTGTCGCTGAAAAGATCGATCTCAGGATCCCAACCGGGTTGCTGAACAACCTGATCAGCAGGTACACCTTAT
CAACACCGCCTGTCGGGCGGAAAAACAAAAAGGCCAAAATCTATTACGCGGCACAAATTGATACAAGACCCCCTCTGATA
ATGCTGAAGGTCAACGATCCAGCATTGTTTACGGAGCCATACCTGAGAGGGATAAGATCAACAATAAGAATGAATATTGA
TCCCTTCGAGGGAACACCAATATTTATAAAGTTGAGGCGTAAAAAATGA

Upstream 100 bases:

>100_bases
AAAAAGCTTTAGAAGAGCTTTCAGGCGAAGAGAGTTCCACGCTTTCCCTTGGTGAGAAGTTGAAGGAACATCTTGAGAAA
AACTCGGAGGGAGAAAAGTA

Downstream 100 bases:

>100_bases
GGTTTATCTGGTTGGCTATTATAGGTTACCTTTTTGGTTCAATTCCTTGGGGATATATAATCCCAAAACTCAGAGGCATA
GACATAAGAAAGGTCGGTAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MATVLIVGRPNVGKSTLFNRLVGGRRAIIDDQPGVTRDFVFGRVFWQHKSFEVVDTCGLFDSPKDIIEEKMKEVTLALLS
EGDLLLFVVDGRKGLTSADMDIAETLRKSKKRVILVANKVENVDKFTLEVLPELYSLGFGEPIPISAEHGLNIDVLLEKI
IKTLEEAGHLLDYEPEKEEDNLKVAIIGKPNAGKSSLFNSIVGSDRSLVTEIPGTTRDMVDETIEIDGMPVTFIDTAGMR
RKSKVGVKNVEYYSVMRAVDAIERSDICILVIDATLGISNQDQRIAGLVEKRGKGIITVFNKSDLLNEKHKESLLSSFER
ELYFIDYSPVVFTSATEGFGIDELLDKLFLVAEKIDLRIPTGLLNNLISRYTLSTPPVGRKNKKAKIYYAAQIDTRPPLI
MLKVNDPALFTEPYLRGIRSTIRMNIDPFEGTPIFIKLRRKK

Sequences:

>Translated_442_residues
MATVLIVGRPNVGKSTLFNRLVGGRRAIIDDQPGVTRDFVFGRVFWQHKSFEVVDTCGLFDSPKDIIEEKMKEVTLALLS
EGDLLLFVVDGRKGLTSADMDIAETLRKSKKRVILVANKVENVDKFTLEVLPELYSLGFGEPIPISAEHGLNIDVLLEKI
IKTLEEAGHLLDYEPEKEEDNLKVAIIGKPNAGKSSLFNSIVGSDRSLVTEIPGTTRDMVDETIEIDGMPVTFIDTAGMR
RKSKVGVKNVEYYSVMRAVDAIERSDICILVIDATLGISNQDQRIAGLVEKRGKGIITVFNKSDLLNEKHKESLLSSFER
ELYFIDYSPVVFTSATEGFGIDELLDKLFLVAEKIDLRIPTGLLNNLISRYTLSTPPVGRKNKKAKIYYAAQIDTRPPLI
MLKVNDPALFTEPYLRGIRSTIRMNIDPFEGTPIFIKLRRKK
>Mature_441_residues
ATVLIVGRPNVGKSTLFNRLVGGRRAIIDDQPGVTRDFVFGRVFWQHKSFEVVDTCGLFDSPKDIIEEKMKEVTLALLSE
GDLLLFVVDGRKGLTSADMDIAETLRKSKKRVILVANKVENVDKFTLEVLPELYSLGFGEPIPISAEHGLNIDVLLEKII
KTLEEAGHLLDYEPEKEEDNLKVAIIGKPNAGKSSLFNSIVGSDRSLVTEIPGTTRDMVDETIEIDGMPVTFIDTAGMRR
KSKVGVKNVEYYSVMRAVDAIERSDICILVIDATLGISNQDQRIAGLVEKRGKGIITVFNKSDLLNEKHKESLLSSFERE
LYFIDYSPVVFTSATEGFGIDELLDKLFLVAEKIDLRIPTGLLNNLISRYTLSTPPVGRKNKKAKIYYAAQIDTRPPLIM
LKVNDPALFTEPYLRGIRSTIRMNIDPFEGTPIFIKLRRKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Homo sapiens, GI193082991, Length=149, Percent_Identity=34.8993288590604, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI193082988, Length=149, Percent_Identity=34.8993288590604, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI193082993, Length=140, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082120, Length=464, Percent_Identity=35.1293103448276, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI2367268, Length=96, Percent_Identity=46.875, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788919, Length=192, Percent_Identity=34.8958333333333, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17507259, Length=192, Percent_Identity=30.2083333333333, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=35.2601156069364, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550813, Length=159, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_KOSOT (C5CIV1)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002939944.1
- GeneID:   7968367
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_0215
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49451; Mature: 49320

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVLIVGRPNVGKSTLFNRLVGGRRAIIDDQPGVTRDFVFGRVFWQHKSFEVVDTCGLF
CEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHEECCCCCEEEEECCCC
DSPKDIIEEKMKEVTLALLSEGDLLLFVVDGRKGLTSADMDIAETLRKSKKRVILVANKV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCC
ENVDKFTLEVLPELYSLGFGEPIPISAEHGLNIDVLLEKIIKTLEEAGHLLDYEPEKEED
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NLKVAIIGKPNAGKSSLFNSIVGSDRSLVTEIPGTTRDMVDETIEIDGMPVTFIDTAGMR
CEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHEEECCCCEEEEECCCCC
RKSKVGVKNVEYYSVMRAVDAIERSDICILVIDATLGISNQDQRIAGLVEKRGKGIITVF
CHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEE
NKSDLLNEKHKESLLSSFERELYFIDYSPVVFTSATEGFGIDELLDKLFLVAEKIDLRIP
CCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCEECC
TGLLNNLISRYTLSTPPVGRKNKKAKIYYAAQIDTRPPLIMLKVNDPALFTEPYLRGIRS
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCEEHHHHHHHHHH
TIRMNIDPFEGTPIFIKLRRKK
HHEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
ATVLIVGRPNVGKSTLFNRLVGGRRAIIDDQPGVTRDFVFGRVFWQHKSFEVVDTCGLF
EEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHEECCCCCEEEEECCCC
DSPKDIIEEKMKEVTLALLSEGDLLLFVVDGRKGLTSADMDIAETLRKSKKRVILVANKV
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCC
ENVDKFTLEVLPELYSLGFGEPIPISAEHGLNIDVLLEKIIKTLEEAGHLLDYEPEKEED
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NLKVAIIGKPNAGKSSLFNSIVGSDRSLVTEIPGTTRDMVDETIEIDGMPVTFIDTAGMR
CEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHEEECCCCEEEEECCCCC
RKSKVGVKNVEYYSVMRAVDAIERSDICILVIDATLGISNQDQRIAGLVEKRGKGIITVF
CHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEE
NKSDLLNEKHKESLLSSFERELYFIDYSPVVFTSATEGFGIDELLDKLFLVAEKIDLRIP
CCHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCEECC
TGLLNNLISRYTLSTPPVGRKNKKAKIYYAAQIDTRPPLIMLKVNDPALFTEPYLRGIRS
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCEEHHHHHHHHHH
TIRMNIDPFEGTPIFIKLRRKK
HHEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA