Click here to switch to the map view.

The map label for this gene is speA [H]

Identifier: 238925621

GI number: 238925621

Start: 3111795

End: 3113267

Strand: Reverse

Name: speA [H]

Synonym: EUBREC_3277

Alternate gene names: 238925621

Gene position: 3113267-3111795 (Counterclockwise)

Preceding gene: 238925622

Following gene: 238925620

Centisome position: 90.25

GC content: 47.05

Gene sequence:

>1473_bases
ATGGAAAAAGAACTGATAAATAATTCACAATCAAATATTTATCCGTTTCACATGCCGGGGCATAAGCGCCGTGGCAGTGA
TATAGGTGCAGGGCTGGACCCGTATGCTATTGATATCACAGAGATAGACAATTTTGACAATCTGCACCACGCTGAGGGCA
TTATAAAGGAGGCGCAGGCTGAGGCAGCGGCGCTTTACGGTGCAAAGCATGCATATTTTCTCATAAACGGAAGCACCTGC
GGTATATTGGCGGCAATATCTGCGGCCACAAAAAGGGGAGACAAGGTGCTTGTAGCAAGGAACTGTCACAAGGCGGTGTA
TCATGCGCTTTACTTAAGGCAGCTTCACCCGGTGTTTACATACCCTGAAATTACACGGACAGGGCTGCAGGGGCAGATAA
CCGAGGCACAGATAAGGGCGGCATTTGATGAAAATCCCGACATAAAAGCGGTTGTGATAACCTCGCCTACATACGATGGT
GTGGTTTCCGATGTGGCGGCAATCGCATCTGTGGCACATGAATATGGAGCTTTACTCATAGTCGACGAGGCACATGGCGC
GCATTTTGGCTTTGGAGGCGGCTTCCCTCAGAATGCCATAGCGCTCGGGGCCGATGCGGTCATAGTGAGCCTGCACAAGA
CGCTTCCGGCATTTACACAGACGGCGCTTTTACTGCTTGGTGGGATGCGTGAAGCTGCAGTGGAGAAGTTTCTCGGCATT
TATGAGACAAGCTCACCGTCATATGTGCTTATGACAGGCATAGAGCGCTGCATACACTATGTGCGCGATAATAAAGAGAC
AGCATTTGCACAGCTTAGGAGCAGGCTTGACAGATTTTATCAGAAGGTCAGCGGACTTTCGCATCTGAGTGTGGTCAGAA
AAAGTGATTTTTCTGCTGACGAGGCATATGATTTTGACGAGTCAAAGATTATTATATTTACGAAAGAGGCTATGAATGGA
CATACGCTGCTTGAGCTTCTGCTCAAAAAATATGAGCTGCAGCTTGAGATGGCAGCGGGCAATTATGTACTGGCGCTGGC
ATCTGTCATGGATACGGATGAGGGCTTTGACAGGCTTGCGGATGCTTTGATTGAAATAGACAGCCGGCTCGAAAAATATA
AGTCTGATTTTGAAGAGTTTTATGATATATTAAAACAGGAGGGTGTGGTACATCAATTTTACTTTCCTGTCAAAATGGAT
ACAACCATATACCAAAAGCTGCCTGCCGTAATGGAAATGTATGATGCATATGATGCAGACCATCAGGAGGTCTATGCCTT
TAAGGCAAGCGGGAAGGTGAGCGGTGCCTTTATAAATATATATCCGCCGGGGATACCGCTTGTGGTGCCGGGAGAGATAA
TGAACGACAAGCTCATAGATGATGTAATAAAGGCTGTAAATTCAGGTCTTGAAGTGGATGGCCTGTACTTTGATCCGGAT
GCCGATATGTGGAAGTTTGTTGCGGTGCTGTAA

Upstream 100 bases:

>100_bases
ACCGGTCTGGAGCGCGTTCTGCAACGATGAAATATTTTATGATGACTGGATGCCGGAGCTTGGAAGATTTCTGGGCTAAA
AAGGATATATAGGTACTTAA

Downstream 100 bases:

>100_bases
GCAACAGTTTGACATAGCAAACAATCATATTTATACTAATTACAATATTAAGAGGTTTACAGATGGGTAAGATTTTCTGC
GTGATGGGAAAAAGCGCATC

Product: arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MEKELINNSQSNIYPFHMPGHKRRGSDIGAGLDPYAIDITEIDNFDNLHHAEGIIKEAQAEAAALYGAKHAYFLINGSTC
GILAAISAATKRGDKVLVARNCHKAVYHALYLRQLHPVFTYPEITRTGLQGQITEAQIRAAFDENPDIKAVVITSPTYDG
VVSDVAAIASVAHEYGALLIVDEAHGAHFGFGGGFPQNAIALGADAVIVSLHKTLPAFTQTALLLLGGMREAAVEKFLGI
YETSSPSYVLMTGIERCIHYVRDNKETAFAQLRSRLDRFYQKVSGLSHLSVVRKSDFSADEAYDFDESKIIIFTKEAMNG
HTLLELLLKKYELQLEMAAGNYVLALASVMDTDEGFDRLADALIEIDSRLEKYKSDFEEFYDILKQEGVVHQFYFPVKMD
TTIYQKLPAVMEMYDAYDADHQEVYAFKASGKVSGAFINIYPPGIPLVVPGEIMNDKLIDDVIKAVNSGLEVDGLYFDPD
ADMWKFVAVL

Sequences:

>Translated_490_residues
MEKELINNSQSNIYPFHMPGHKRRGSDIGAGLDPYAIDITEIDNFDNLHHAEGIIKEAQAEAAALYGAKHAYFLINGSTC
GILAAISAATKRGDKVLVARNCHKAVYHALYLRQLHPVFTYPEITRTGLQGQITEAQIRAAFDENPDIKAVVITSPTYDG
VVSDVAAIASVAHEYGALLIVDEAHGAHFGFGGGFPQNAIALGADAVIVSLHKTLPAFTQTALLLLGGMREAAVEKFLGI
YETSSPSYVLMTGIERCIHYVRDNKETAFAQLRSRLDRFYQKVSGLSHLSVVRKSDFSADEAYDFDESKIIIFTKEAMNG
HTLLELLLKKYELQLEMAAGNYVLALASVMDTDEGFDRLADALIEIDSRLEKYKSDFEEFYDILKQEGVVHQFYFPVKMD
TTIYQKLPAVMEMYDAYDADHQEVYAFKASGKVSGAFINIYPPGIPLVVPGEIMNDKLIDDVIKAVNSGLEVDGLYFDPD
ADMWKFVAVL
>Mature_490_residues
MEKELINNSQSNIYPFHMPGHKRRGSDIGAGLDPYAIDITEIDNFDNLHHAEGIIKEAQAEAAALYGAKHAYFLINGSTC
GILAAISAATKRGDKVLVARNCHKAVYHALYLRQLHPVFTYPEITRTGLQGQITEAQIRAAFDENPDIKAVVITSPTYDG
VVSDVAAIASVAHEYGALLIVDEAHGAHFGFGGGFPQNAIALGADAVIVSLHKTLPAFTQTALLLLGGMREAAVEKFLGI
YETSSPSYVLMTGIERCIHYVRDNKETAFAQLRSRLDRFYQKVSGLSHLSVVRKSDFSADEAYDFDESKIIIFTKEAMNG
HTLLELLLKKYELQLEMAAGNYVLALASVMDTDEGFDRLADALIEIDSRLEKYKSDFEEFYDILKQEGVVHQFYFPVKMD
TTIYQKLPAVMEMYDAYDADHQEVYAFKASGKVSGAFINIYPPGIPLVVPGEIMNDKLIDDVIKAVNSGLEVDGLYFDPD
ADMWKFVAVL

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=530, Percent_Identity=21.3207547169811, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786384, Length=276, Percent_Identity=26.4492753623188, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54206; Mature: 54206

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKELINNSQSNIYPFHMPGHKRRGSDIGAGLDPYAIDITEIDNFDNLHHAEGIIKEAQA
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
EAAALYGAKHAYFLINGSTCGILAAISAATKRGDKVLVARNCHKAVYHALYLRQLHPVFT
HHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCC
YPEITRTGLQGQITEAQIRAAFDENPDIKAVVITSPTYDGVVSDVAAIASVAHEYGALLI
CCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEE
VDEAHGAHFGFGGGFPQNAIALGADAVIVSLHKTLPAFTQTALLLLGGMREAAVEKFLGI
EECCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YETSSPSYVLMTGIERCIHYVRDNKETAFAQLRSRLDRFYQKVSGLSHLSVVRKSDFSAD
EECCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
EAYDFDESKIIIFTKEAMNGHTLLELLLKKYELQLEMAAGNYVLALASVMDTDEGFDRLA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHHHHHHH
DALIEIDSRLEKYKSDFEEFYDILKQEGVVHQFYFPVKMDTTIYQKLPAVMEMYDAYDAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHCCCC
HQEVYAFKASGKVSGAFINIYPPGIPLVVPGEIMNDKLIDDVIKAVNSGLEVDGLYFDPD
CCEEEEEECCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCEECCEEECCC
ADMWKFVAVL
CCHHHHHHCC
>Mature Secondary Structure
MEKELINNSQSNIYPFHMPGHKRRGSDIGAGLDPYAIDITEIDNFDNLHHAEGIIKEAQA
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
EAAALYGAKHAYFLINGSTCGILAAISAATKRGDKVLVARNCHKAVYHALYLRQLHPVFT
HHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCC
YPEITRTGLQGQITEAQIRAAFDENPDIKAVVITSPTYDGVVSDVAAIASVAHEYGALLI
CCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEE
VDEAHGAHFGFGGGFPQNAIALGADAVIVSLHKTLPAFTQTALLLLGGMREAAVEKFLGI
EECCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YETSSPSYVLMTGIERCIHYVRDNKETAFAQLRSRLDRFYQKVSGLSHLSVVRKSDFSAD
EECCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
EAYDFDESKIIIFTKEAMNGHTLLELLLKKYELQLEMAAGNYVLALASVMDTDEGFDRLA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHHHHHHH
DALIEIDSRLEKYKSDFEEFYDILKQEGVVHQFYFPVKMDTTIYQKLPAVMEMYDAYDAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHCCCC
HQEVYAFKASGKVSGAFINIYPPGIPLVVPGEIMNDKLIDDVIKAVNSGLEVDGLYFDPD
CCEEEEEECCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCEECCEEECCC
ADMWKFVAVL
CCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]