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The map label for this gene is moaA [H]

Identifier: 238925509

GI number: 238925509

Start: 3016561

End: 3017634

Strand: Reverse

Name: moaA [H]

Synonym: EUBREC_3165

Alternate gene names: 238925509

Gene position: 3017634-3016561 (Counterclockwise)

Preceding gene: 238925510

Following gene: 238925508

Centisome position: 87.48

GC content: 43.3

Gene sequence:

>1074_bases
ATGCGCGATAGATTTGGCAGAGAGATTGACTACATGCGCATATCGGTGATAGATAGCTGTAATCTGAACTGTTATTATTG
CAACCCACAGGACAATAATAAAAATTGTCAGGCAATAAATATACTTAGCGTAAAAAAGGTGCTTTGTATAGTCCGCGCAG
CCACAAGGATTGGAATCACGCATTTTCGTCTGACAGGCGGTGAGCCGCTTCTGCATCCGCAGATTGATGAGATGGTTTCA
CAAATCAAAAAGATACCCGGTGTCAGGAGTGTATCACTCACCACAAACGCAGTATTGCTTGCGCAGCATGCAAAGCAGCT
TAAGGAAGCCGGCATAGACAGTATAAATGTGAGCCTGGACACGATAGATGCGTCAGAATATGAACATATCACAAAAAAAC
CGCTGCTTCATAAAGTAGAGCATGGAATCGATGCTGCCATAGAGTGTGGAATAAGAGTGAAAATCAATGTGGTGCTCACA
CCGCAGACAGATGTGGTGGCTCTCACACGGTATGCTTCCAAAAAAGGCACAGATATCCGTTTTATAGAGATGATGCCGGT
AGGTGAAGGGCATACCAACGGAGTCGAGCCGTATGAGAAGGTTATTGGCGCACTTTTAGAAGTATATGGAACTTTTTGCC
ATATAGATACTGAAAATAGAGAAGAAATTAATTCGGGATATAATAATTCAGATAACGGTCCGGCAGAGTATTACAGTTTT
CATGGACTTAATATCAGAGTAGGGCTGATTCAGGCAATCCATGGGAAGTTCTGCGATACCTGTAACCGCATACGTGTTAC
GGCTGACGGCAGGCTTATGCCATGCCTGGGAAGCAGCGTGACGATGGATTTAGTACCTGATTCATGCGAATTTACAGATG
ATTTGGAAAAAGATTTTGTAATAGTTCAGGCACTAAAGGCTGCCATAAAGGCAAAGCCGGGGTGTCACAATTTTAATGAT
AATGCAGTGACATATACAAAAACTACAGAGACAAAGACTGTAGAGACAAAGGCTACAGAGCTGAAAGCTGCGGAAGTAAA
TGCAGCAAGAAATATGAGCCGGATAGGAGGCTGA

Upstream 100 bases:

>100_bases
ATTTTGGCAGATGAGCTTGCCGGACTTGGAGAAGGCGGACTCTGCCTGAATTGTGATGTCTGTACGTTTCCTAACTGCGG
TTTCGGGAAGGGCTTTTAAT

Downstream 100 bases:

>100_bases
TAGCAAATCATGGGAAAGCTTCTTGCAATCAATATAAGCAAAGAGAGAGGAACTGAAAAGAGAGAGGTGCCACAGGCGGA
GCTTGTTGCAGACTATGGCA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRDRFGREIDYMRISVIDSCNLNCYYCNPQDNNKNCQAINILSVKKVLCIVRAATRIGITHFRLTGGEPLLHPQIDEMVS
QIKKIPGVRSVSLTTNAVLLAQHAKQLKEAGIDSINVSLDTIDASEYEHITKKPLLHKVEHGIDAAIECGIRVKINVVLT
PQTDVVALTRYASKKGTDIRFIEMMPVGEGHTNGVEPYEKVIGALLEVYGTFCHIDTENREEINSGYNNSDNGPAEYYSF
HGLNIRVGLIQAIHGKFCDTCNRIRVTADGRLMPCLGSSVTMDLVPDSCEFTDDLEKDFVIVQALKAAIKAKPGCHNFND
NAVTYTKTTETKTVETKATELKAAEVNAARNMSRIGG

Sequences:

>Translated_357_residues
MRDRFGREIDYMRISVIDSCNLNCYYCNPQDNNKNCQAINILSVKKVLCIVRAATRIGITHFRLTGGEPLLHPQIDEMVS
QIKKIPGVRSVSLTTNAVLLAQHAKQLKEAGIDSINVSLDTIDASEYEHITKKPLLHKVEHGIDAAIECGIRVKINVVLT
PQTDVVALTRYASKKGTDIRFIEMMPVGEGHTNGVEPYEKVIGALLEVYGTFCHIDTENREEINSGYNNSDNGPAEYYSF
HGLNIRVGLIQAIHGKFCDTCNRIRVTADGRLMPCLGSSVTMDLVPDSCEFTDDLEKDFVIVQALKAAIKAKPGCHNFND
NAVTYTKTTETKTVETKATELKAAEVNAARNMSRIGG
>Mature_357_residues
MRDRFGREIDYMRISVIDSCNLNCYYCNPQDNNKNCQAINILSVKKVLCIVRAATRIGITHFRLTGGEPLLHPQIDEMVS
QIKKIPGVRSVSLTTNAVLLAQHAKQLKEAGIDSINVSLDTIDASEYEHITKKPLLHKVEHGIDAAIECGIRVKINVVLT
PQTDVVALTRYASKKGTDIRFIEMMPVGEGHTNGVEPYEKVIGALLEVYGTFCHIDTENREEINSGYNNSDNGPAEYYSF
HGLNIRVGLIQAIHGKFCDTCNRIRVTADGRLMPCLGSSVTMDLVPDSCEFTDDLEKDFVIVQALKAAIKAKPGCHNFND
NAVTYTKTTETKTVETKATELKAAEVNAARNMSRIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=280, Percent_Identity=33.9285714285714, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI22027536, Length=280, Percent_Identity=33.9285714285714, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1786999, Length=337, Percent_Identity=31.1572700296736, Blast_Score=154, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI32566331, Length=279, Percent_Identity=32.9749103942652, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI32566329, Length=279, Percent_Identity=32.9749103942652, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17561210, Length=279, Percent_Identity=32.258064516129, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574490, Length=281, Percent_Identity=32.0284697508897, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28574488, Length=279, Percent_Identity=32.258064516129, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 39462; Mature: 39462

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRFGREIDYMRISVIDSCNLNCYYCNPQDNNKNCQAINILSVKKVLCIVRAATRIGIT
CCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCEE
HFRLTGGEPLLHPQIDEMVSQIKKIPGVRSVSLTTNAVLLAQHAKQLKEAGIDSINVSLD
EEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEE
TIDASEYEHITKKPLLHKVEHGIDAAIECGIRVKINVVLTPQTDVVALTRYASKKGTDIR
ECCCHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEEEECCCCCEEEHHHHHCCCCCCEE
FIEMMPVGEGHTNGVEPYEKVIGALLEVYGTFCHIDTENREEINSGYNNSDNGPAEYYSF
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHCCCCCCCCCCCCEEEE
HGLNIRVGLIQAIHGKFCDTCNRIRVTADGRLMPCLGSSVTMDLVPDSCEFTDDLEKDFV
CCCEEEEHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCHHHHHHH
IVQALKAAIKAKPGCHNFNDNAVTYTKTTETKTVETKATELKAAEVNAARNMSRIGG
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDRFGREIDYMRISVIDSCNLNCYYCNPQDNNKNCQAINILSVKKVLCIVRAATRIGIT
CCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCEE
HFRLTGGEPLLHPQIDEMVSQIKKIPGVRSVSLTTNAVLLAQHAKQLKEAGIDSINVSLD
EEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEE
TIDASEYEHITKKPLLHKVEHGIDAAIECGIRVKINVVLTPQTDVVALTRYASKKGTDIR
ECCCHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEEEECCCCCEEEHHHHHCCCCCCEE
FIEMMPVGEGHTNGVEPYEKVIGALLEVYGTFCHIDTENREEINSGYNNSDNGPAEYYSF
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHCCCCCCCCCCCCEEEE
HGLNIRVGLIQAIHGKFCDTCNRIRVTADGRLMPCLGSSVTMDLVPDSCEFTDDLEKDFV
CCCEEEEHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCHHHHHHH
IVQALKAAIKAKPGCHNFNDNAVTYTKTTETKTVETKATELKAAEVNAARNMSRIGG
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA