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The map label for this gene is fabD [H]

Identifier: 238925490

GI number: 238925490

Start: 2996947

End: 2997873

Strand: Reverse

Name: fabD [H]

Synonym: EUBREC_3146

Alternate gene names: 238925490

Gene position: 2997873-2996947 (Counterclockwise)

Preceding gene: 238925491

Following gene: 238925489

Centisome position: 86.9

GC content: 46.71

Gene sequence:

>927_bases
ATGGGTAAGAGAGTATTTATGTTTCCCGGACAGGGCTCACAGTATATAGGAATGGGTAAGGAGTTTTACGATACAATGCC
AAATGCAAAGGCAGTAATCGACCTTGCCAGTGAACAGACAGGCTTGGATATTCCGGCATTATGCTTTGAGGAAAATGACA
AGCTGAATATTACAGAGTACACACAGATATGTATGCTTGCAGTTGAGGCAGCTATATATCAGGCAATCATTGACAAAGGT
ATCACACCTGATGTCACAGCTGGATTAAGCCTTGGGGAATATGGTGCTCTCATCGCATCAGGAGCCATGACTATGGCAGA
TGCATTTGCAGTTGTCAGAAAAAGAGGAATCTACATGCAGGAGGCAGTTCCTACAGGTGGAGCCATGACAGCGGTTTTAG
GACTTGATCCGCAGGTCATTGAGGATATATGCAAAAAGACAGCAGATGAGACAAATTCAGTTGTATCGGTAGCCAACTAT
AACTGCCCTGGGCAGATTGTTATCACGGGAGAAAAGGTAGCAGTAGATGCCGCCGCAGCAGCATGCAGCGAGGCAGGCGC
CAAGAGATGCGTACCGCTCAAGGTCAGCGGACCTTTCCACTCAGCAATGCTTAAGGGTGCAGGAGAAAAGCTCGCAGATG
CACTTGAGAGTGTAGAAATCCACGATATCAAGGTGCCATATATCACAAACGTCACAGCAGACTATGTGAAGTCACCGGCA
GACGTCAAGGATTATCTGACACAGCAGGTTTCATCGTCAGTGCGCTGGCAGCAGACCATCGAGCGTCTTATCGCAGACGG
TGCAGATGAGTTCGTGGAAATCGGACCGGGACGCTCACTCAGCGGATTTATGAGAAAGATAAATAGAGACGTAAAAGTCG
TAAACATAGACAAACTGGAGGATTTTGAAAAGTATGTTAACAGGTAA

Upstream 100 bases:

>100_bases
CAAATAGACAGTATTCACTTTTACATGCAAATTTAAGGATACCGGGCCGCCTGGAAAGAGTGGCTTACGGTATCCTGTCA
GAAATAAGGAGAAACCGAAA

Downstream 100 bases:

>100_bases
AAATGCCCTGGTTACAGGCGCAAGCCGCGGAATTGGAAGACAGATAGCTCTTACACTTGCCGCAGCACACGCCTTTGTAA
TAGTAAATTATAATGGTTCA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MGKRVFMFPGQGSQYIGMGKEFYDTMPNAKAVIDLASEQTGLDIPALCFEENDKLNITEYTQICMLAVEAAIYQAIIDKG
ITPDVTAGLSLGEYGALIASGAMTMADAFAVVRKRGIYMQEAVPTGGAMTAVLGLDPQVIEDICKKTADETNSVVSVANY
NCPGQIVITGEKVAVDAAAAACSEAGAKRCVPLKVSGPFHSAMLKGAGEKLADALESVEIHDIKVPYITNVTADYVKSPA
DVKDYLTQQVSSSVRWQQTIERLIADGADEFVEIGPGRSLSGFMRKINRDVKVVNIDKLEDFEKYVNR

Sequences:

>Translated_308_residues
MGKRVFMFPGQGSQYIGMGKEFYDTMPNAKAVIDLASEQTGLDIPALCFEENDKLNITEYTQICMLAVEAAIYQAIIDKG
ITPDVTAGLSLGEYGALIASGAMTMADAFAVVRKRGIYMQEAVPTGGAMTAVLGLDPQVIEDICKKTADETNSVVSVANY
NCPGQIVITGEKVAVDAAAAACSEAGAKRCVPLKVSGPFHSAMLKGAGEKLADALESVEIHDIKVPYITNVTADYVKSPA
DVKDYLTQQVSSSVRWQQTIERLIADGADEFVEIGPGRSLSGFMRKINRDVKVVNIDKLEDFEKYVNR
>Mature_307_residues
GKRVFMFPGQGSQYIGMGKEFYDTMPNAKAVIDLASEQTGLDIPALCFEENDKLNITEYTQICMLAVEAAIYQAIIDKGI
TPDVTAGLSLGEYGALIASGAMTMADAFAVVRKRGIYMQEAVPTGGAMTAVLGLDPQVIEDICKKTADETNSVVSVANYN
CPGQIVITGEKVAVDAAAAACSEAGAKRCVPLKVSGPFHSAMLKGAGEKLADALESVEIHDIKVPYITNVTADYVKSPAD
VKDYLTQQVSSSVRWQQTIERLIADGADEFVEIGPGRSLSGFMRKINRDVKVVNIDKLEDFEKYVNR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=306, Percent_Identity=32.3529411764706, Blast_Score=132, Evalue=3e-31,
Organism=Escherichia coli, GI1787334, Length=290, Percent_Identity=40, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=31.4189189189189, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=25.4237288135593, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=28.6666666666667, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33139; Mature: 33008

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRVFMFPGQGSQYIGMGKEFYDTMPNAKAVIDLASEQTGLDIPALCFEENDKLNITEY
CCCEEEEECCCCCCEECCCHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHH
TQICMLAVEAAIYQAIIDKGITPDVTAGLSLGEYGALIASGAMTMADAFAVVRKRGIYMQ
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVPTGGAMTAVLGLDPQVIEDICKKTADETNSVVSVANYNCPGQIVITGEKVAVDAAAA
HCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCHHHHHHHHH
ACSEAGAKRCVPLKVSGPFHSAMLKGAGEKLADALESVEIHDIKVPYITNVTADYVKSPA
HHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCEEEEEECCEEECCCHHHHCCCC
DVKDYLTQQVSSSVRWQQTIERLIADGADEFVEIGPGRSLSGFMRKINRDVKVVNIDKLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHCCCEEEEEHHHHH
DFEKYVNR
HHHHHHCC
>Mature Secondary Structure 
GKRVFMFPGQGSQYIGMGKEFYDTMPNAKAVIDLASEQTGLDIPALCFEENDKLNITEY
CCEEEEECCCCCCEECCCHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHH
TQICMLAVEAAIYQAIIDKGITPDVTAGLSLGEYGALIASGAMTMADAFAVVRKRGIYMQ
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVPTGGAMTAVLGLDPQVIEDICKKTADETNSVVSVANYNCPGQIVITGEKVAVDAAAA
HCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCHHHHHHHHH
ACSEAGAKRCVPLKVSGPFHSAMLKGAGEKLADALESVEIHDIKVPYITNVTADYVKSPA
HHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCEEEEEECCEEECCCHHHHCCCC
DVKDYLTQQVSSSVRWQQTIERLIADGADEFVEIGPGRSLSGFMRKINRDVKVVNIDKLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHCCCEEEEEHHHHH
DFEKYVNR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]