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The map label for this gene is ribD [H]

Identifier: 238925477

GI number: 238925477

Start: 2985565

End: 2986749

Strand: Reverse

Name: ribD [H]

Synonym: EUBREC_3132

Alternate gene names: 238925477

Gene position: 2986749-2985565 (Counterclockwise)

Preceding gene: 238925478

Following gene: 238925476

Centisome position: 86.58

GC content: 45.49

Gene sequence:

>1185_bases
ATGCAGAAAGGAACCCAAATGACTGATGAACAATATATGAGAAGGGCGATTGAGCTTGCAAAACGCGGCATGGGATATAC
CTCGCCAAACCCGATGGTCGGAGCTGTGATTGTAAAGGACGGCAGGATAATCGGAGAGGGCTGGCATGAGAGATACGGAG
AGCTGCACGCGGAAAGAAATGCGTTAAAGCATTGCAAGGAATCGCCACAGGGAGCGGATATGTATGTGACTCTCGAGCCA
TGCTGTCATCATGGCAAGCAGCCGCCATGTGTGGAGGCAGTGATAGAAGCCGGTATAAAAAGAGTATATGTGGGCTCGGA
TGACCCGAATCCGCTTGTCGCCGGGGGAGGTATCAAAATCCTTAAAGAGCATGGGATAGAGGTTGTTACGCAGGTGCTTA
AAGACGAGTGCGACAGGCTGAACGATGTATTCTTTTACTTTATACAGACCAGACGTCCATATGTCGCTATGAAATATGCC
ATGACGATGGATGGAAAGATAGCCACATATTCAGGACTATCAAAGTGGATAACAGGAGAAAAAGCGAGAGAACATGTGCA
AAACCTGCGCCACAGATATAAAGCCATAATGGCAGGAATAGGAACAGTGCTTGCAGACGATCCACTGCTTACATGCAGAA
TCGAGGGCGGAGTAAATCCAATCCGCATAATATGCGATACGCACCTTAAGCTTCCACTGGAATCGCAGATAGTAAATACT
GCAAAGGAAGTGCCGACGATTGTTGCAGTCAGTGAGCGATATCATGAAACCGCACAGTCAGAAGCCTTACCTGATACTGA
AAAAGATAGTATAGAAGAAAACAATAATTATCAAAAAAACAGAAAAATAACACGGCTTGAAGAAAACGGAATAGAAATTC
TGTATGTAGCTGAAAAAAACGGTCATATTGATTTAAATGACCTCATGCAAAAGCTCGGCGAAAGAAGCATAGACAGCATT
TTGCTTGAGGGAGGCGGAATACTCAACTGGTCAGCCCTTAAGAGCGGGATTGTGAATAAGGTATACGCTTACATTGCACC
AAAGCTTTTCGGAGGGGCGGATGCAAAAACTCCGATAGAGGGAATGGGAACCGACTCGCCGGCACATGCCGTGATGCTTG
GAAACAGTAAGGTAACAAAGCTTGGTGATGATTTCCTCATCGAGAGTGATGTTGTGAATATTTAA

Upstream 100 bases:

>100_bases
CAAAATTCATTTATGATGAAATGCAGCTTGTGCATGTTTATCTGAGATTATGATATTTGAAATCATTAGGCCCTGAACGA
TAATAGTTCAGGGCTTTTTT

Downstream 100 bases:

>100_bases
AAAGAAAGGCGATACACAATGTTCACAGGAATAGTTGAAGAAGTTGGAACAATAGATACAATTTCACGTGGAGCAAACTC
AGCAGTACTTACAATCAGAG

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQKGTQMTDEQYMRRAIELAKRGMGYTSPNPMVGAVIVKDGRIIGEGWHERYGELHAERNALKHCKESPQGADMYVTLEP
CCHHGKQPPCVEAVIEAGIKRVYVGSDDPNPLVAGGGIKILKEHGIEVVTQVLKDECDRLNDVFFYFIQTRRPYVAMKYA
MTMDGKIATYSGLSKWITGEKAREHVQNLRHRYKAIMAGIGTVLADDPLLTCRIEGGVNPIRIICDTHLKLPLESQIVNT
AKEVPTIVAVSERYHETAQSEALPDTEKDSIEENNNYQKNRKITRLEENGIEILYVAEKNGHIDLNDLMQKLGERSIDSI
LLEGGGILNWSALKSGIVNKVYAYIAPKLFGGADAKTPIEGMGTDSPAHAVMLGNSKVTKLGDDFLIESDVVNI

Sequences:

>Translated_394_residues
MQKGTQMTDEQYMRRAIELAKRGMGYTSPNPMVGAVIVKDGRIIGEGWHERYGELHAERNALKHCKESPQGADMYVTLEP
CCHHGKQPPCVEAVIEAGIKRVYVGSDDPNPLVAGGGIKILKEHGIEVVTQVLKDECDRLNDVFFYFIQTRRPYVAMKYA
MTMDGKIATYSGLSKWITGEKAREHVQNLRHRYKAIMAGIGTVLADDPLLTCRIEGGVNPIRIICDTHLKLPLESQIVNT
AKEVPTIVAVSERYHETAQSEALPDTEKDSIEENNNYQKNRKITRLEENGIEILYVAEKNGHIDLNDLMQKLGERSIDSI
LLEGGGILNWSALKSGIVNKVYAYIAPKLFGGADAKTPIEGMGTDSPAHAVMLGNSKVTKLGDDFLIESDVVNI
>Mature_394_residues
MQKGTQMTDEQYMRRAIELAKRGMGYTSPNPMVGAVIVKDGRIIGEGWHERYGELHAERNALKHCKESPQGADMYVTLEP
CCHHGKQPPCVEAVIEAGIKRVYVGSDDPNPLVAGGGIKILKEHGIEVVTQVLKDECDRLNDVFFYFIQTRRPYVAMKYA
MTMDGKIATYSGLSKWITGEKAREHVQNLRHRYKAIMAGIGTVLADDPLLTCRIEGGVNPIRIICDTHLKLPLESQIVNT
AKEVPTIVAVSERYHETAQSEALPDTEKDSIEENNNYQKNRKITRLEENGIEILYVAEKNGHIDLNDLMQKLGERSIDSI
LLEGGGILNWSALKSGIVNKVYAYIAPKLFGGADAKTPIEGMGTDSPAHAVMLGNSKVTKLGDDFLIESDVVNI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=394, Percent_Identity=38.0710659898477, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=35.0649350649351, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 43661; Mature: 43661

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGTQMTDEQYMRRAIELAKRGMGYTSPNPMVGAVIVKDGRIIGEGWHERYGELHAERN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHH
ALKHCKESPQGADMYVTLEPCCHHGKQPPCVEAVIEAGIKRVYVGSDDPNPLVAGGGIKI
HHHHHHCCCCCCEEEEEECHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCEEECCCHHH
LKEHGIEVVTQVLKDECDRLNDVFFYFIQTRRPYVAMKYAMTMDGKIATYSGLSKWITGE
HHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCEEEHHHHHHHHCCH
KAREHVQNLRHRYKAIMAGIGTVLADDPLLTCRIEGGVNPIRIICDTHLKLPLESQIVNT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHH
AKEVPTIVAVSERYHETAQSEALPDTEKDSIEENNNYQKNRKITRLEENGIEILYVAEKN
HHHCCEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHCCCEEEEECCCEEEEEEECCC
GHIDLNDLMQKLGERSIDSILLEGGGILNWSALKSGIVNKVYAYIAPKLFGGADAKTPIE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMGTDSPAHAVMLGNSKVTKLGDDFLIESDVVNI
CCCCCCCCEEEEECCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MQKGTQMTDEQYMRRAIELAKRGMGYTSPNPMVGAVIVKDGRIIGEGWHERYGELHAERN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHH
ALKHCKESPQGADMYVTLEPCCHHGKQPPCVEAVIEAGIKRVYVGSDDPNPLVAGGGIKI
HHHHHHCCCCCCEEEEEECHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCEEECCCHHH
LKEHGIEVVTQVLKDECDRLNDVFFYFIQTRRPYVAMKYAMTMDGKIATYSGLSKWITGE
HHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCEEEHHHHHHHHCCH
KAREHVQNLRHRYKAIMAGIGTVLADDPLLTCRIEGGVNPIRIICDTHLKLPLESQIVNT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHH
AKEVPTIVAVSERYHETAQSEALPDTEKDSIEENNNYQKNRKITRLEENGIEILYVAEKN
HHHCCEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHCCCEEEEECCCEEEEEEECCC
GHIDLNDLMQKLGERSIDSILLEGGGILNWSALKSGIVNKVYAYIAPKLFGGADAKTPIE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMGTDSPAHAVMLGNSKVTKLGDDFLIESDVVNI
CCCCCCCCEEEEECCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]